Enhanced lipogenesis through Pparγ helps cavefish adapt to food scarcity

Repeated evolution of circadian clock dysregulation in cavefish populations

(2021) Katya L. Mack et al.   PLoS Genetics

Antarctic blackfin icefish genome reveals adaptations to extreme environments

(2019) Bo-Mi Kim et al.   Nature Ecology & Evolution

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

Early adipogenesis contributes to excess fat accumulation in cave populations of Astyanax mexicanus

(2018) Shaolei Xiong et al.   DEVELOPMENTAL BIOLOGY

Morphogenesis and motility of the Astyanax mexicanus gastrointestinal tract

(2018) Misty R. Riddle et al.   DEVELOPMENTAL BIOLOGY

Development of the Astyanax mexicanus circadian clock and non-visual light responses

(2018) Inga A. Frøland Steindal et al.   DEVELOPMENTAL BIOLOGY

Mutations in blind cavefish target the light-regulated circadian clock gene, period 2

(2018) Rosa Maria Ceinos et al.   Scientific Reports

Developmental evolution of the forebrain in cavefish, from natural variations in neuropeptides to behavior

(2018) Alexandre Alié et al.   eLife

Parallel activation of de novo lipogenesis and stearoyl-CoA desaturase activity after 3 d of high-carbohydrate feeding

(2018) Mary F-F Chong et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The role of gene flow in rapid and repeated evolution of cave related traits in Mexican tetra, Astyanax mexicanus

(2018) Adam Herman et al.   MOLECULAR ECOLOGY

Insulin resistance in cavefish as an adaptation to a nutrient-limited environment

(2018) Misty R. Riddle et al.   NATURE

Hepatocyte-specific, PPARγ-regulated mechanisms to promote steatosis in adult mice

(2016) Abigail Wolf Greenstein et al.   JOURNAL OF ENDOCRINOLOGY

ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization

(2015) Guangchuang Yu et al.   BIOINFORMATICS

Nonalcoholic Fatty Liver Disease

(2015) Mary E. Rinella   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The PPAR-γ antagonist GW9662 elicits differentiation of M2c-like cells and upregulation of the MerTK/Gas6 axis: a key role for PPAR-γ in human macrophage polarization

(2015) Gaetano Zizzo et al.   Journal of Inflammation-London

Transcriptional regulation of hepatic lipogenesis

(2015) Yuhui Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Melanocortin 4 receptor mutations contribute to the adaptation of cavefish to nutrient-poor conditions

(2015) Ariel C. Aspiras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fatty acid desaturation index in human plasma: comparison of different analytical methodologies for the evaluation of diet effects

(2014) Jost Klawitter et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Eyeless Mexican Cavefish Save Energy by Eliminating the Circadian Rhythm in Metabolism

(2014) Damian Moran et al.   PLoS One

PPARγ signaling and metabolism: the good, the bad and the future

(2013) Maryam Ahmadian et al.   NATURE MEDICINE

Circadian rhythms in Mexican blind cavefish Astyanax mexicanus in the lab and in the field

(2013) Andrew Beale et al.   Nature Communications

Software for Computing and Annotating Genomic Ranges

(2013) Michael Lawrence et al.   PLoS Computational Biology

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Nuclear receptor PPAR -regulated monoacylglycerol O-acyltransferase 1 (MGAT1) expression is responsible for the lipid accumulation in diet-induced hepatic steatosis

(2012) Y. J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults

(2011) G. Vernon et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

FIMO: scanning for occurrences of a given motif

(2011) Charles E. Grant et al.   BIOINFORMATICS

Up-Regulation of PPAR-γ mRNA Expression in the Liver of Obese Patients: an Additional Reinforcing Lipogenic Mechanism to SREBP-1c Induction

(2011) Paulina Pettinelli et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

PER2 Controls Lipid Metabolism by Direct Regulation of PPARγ

(2010) Benedetto Grimaldi et al.   Cell Metabolism

rtracklayer: an R package for interfacing with genome browsers

(2009) M. Lawrence et al.   BIOINFORMATICS

Ontogeny and nutritional control of adipogenesis in zebrafish (Danio rerio)

(2009) Edward J. Flynn et al.   JOURNAL OF LIPID RESEARCH

Fat and Beyond: The Diverse Biology of PPARγ

(2008) Peter Tontonoz et al.   Annual Review of Biochemistry

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY

Hepatic Fatty Acid Transporter Cd36 Is a Common Target of LXR, PXR, and PPARγ in Promoting Steatosis

(2007) Jie Zhou et al.   GASTROENTEROLOGY