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Glutaminolysis is Essential for Myofibroblast Persistence and In Vivo Targeting Reverses Fibrosis and Cardiac Dysfunction in Heart Failure

CIRCULATION (2022)

Journal

CIRCULATION

Volume 145, Issue 21, Pages 1625-1628

Publisher

LIPPINCOTT WILLIAMS & WILKINS

DOI: 10.1161/CIRCULATIONAHA.121.057879

Keywords

fibrosis; glutamine; heart failure; metabolism; myofibroblasts

Categories

Cardiac & Cardiovascular Systems Peripheral Vascular Disease

Funding

National Institutes of Health [R01HL123966, R01HL136954, R01HL142271, P01HL134608, F32HL145914, F31HL143913, R01HL152446, R01HL058493, R01HL149891, R01HL105993, R01HL130174]
American Heart Association [20EIA35320226]

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