Comprehensive quantification of metabolic flux during acute cold stress in mice

Impact of acute stress on murine metabolomics and metabolic flux

(2023) Won Dong Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative analysis of metabolic fluxes in brown fat and skeletal muscle during thermogenesis

(2023) Grace Park et al.   Nature Metabolism

Branched-Chain Fatty Acids Alter the Expression of Genes Responsible for Lipid Synthesis and Inflammation in Human Adipose Cells

(2022) Aleksandra Czumaj et al.   Nutrients

Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis

(2021) Anna Whitehead et al.   Nature Communications

Pyruvate carboxylase supports basal ATP-linked respiration in human pluripotent stem cell-derived brown adipocytes

(2021) Udom Lao-On et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

In vivo isotope tracing reveals the versatility of glucose as a brown adipose tissue substrate

(2021) Su Myung Jung et al.   Cell Reports

Signals from the Circle: Tricarboxylic Acid Cycle Intermediates as Myometabokines

(2021) Jennifer Maurer et al.   Metabolites

Branched-Chain Amino Acid Catabolism Promotes Thrombosis Risk by Enhancing Tropomodulin-3 Propionylation in Platelets

(2020) Yanyan Xu et al.   CIRCULATION

FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome

(2020) Fuming Li et al.   NATURE CELL BIOLOGY

Quantitative Fluxomics of Circulating Metabolites

(2020) Sheng Hui et al.   Cell Metabolism

3-Hydroxyisobutyrate, a Strong Marker of Insulin Resistance in Type 2 Diabetes and Obesity That Modulates White and Brown Adipocyte Metabolism

(2020) Mona S. Nilsen et al.   DIABETES

Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis

(2020) Vanja Panic et al.   eLife

Substrate Utilization by Brown Adipose Tissue: What’s Hot and What’s Not?

(2020) Ben T. McNeill et al.   Frontiers in Endocrinology

BCAA catabolism in brown fat controls energy homeostasis through SLC25A44

(2019) Takeshi Yoneshiro et al.   NATURE

2-Aminoadipic acid protects against obesity and diabetes

(2019) Wang-Yang Xu et al.   JOURNAL OF ENDOCRINOLOGY

Glycerol not lactate is the major net carbon source for gluconeogenesis in mice during both short and prolonged fasting

(2019) Yujue Wang et al.   Molecular Metabolism

Metabolomics and Isotope Tracing

(2018) Cholsoon Jang et al.   CELL

Substantial Metabolic Activity of Human Brown Adipose Tissue during Warm Conditions and Cold-Induced Lipolysis of Local Triglycerides

(2018) Graeme Weir et al.   Cell Metabolism

Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis

(2018) Joan Sanchez-Gurmaches et al.   Cell Metabolism

Intracellular glycolysis in brown adipose tissue is essential for optogenetically induced nonshivering thermogenesis in mice

(2018) Jae Hoon Jeong et al.   Scientific Reports

Fatty acid oxidation is required for active and quiescent brown adipose tissue maintenance and thermogenic programing

(2018) Elsie Gonzalez-Hurtado et al.   Molecular Metabolism

Brown adipocyte glucose metabolism: a heated subject

(2018) Mohammed K Hankir et al.   EMBO REPORTS

Accumulation of succinate controls activation of adipose tissue thermogenesis

(2018) Evanna L. Mills et al.   NATURE

Branched Chain Amino Acids

(2018) Michael Neinast et al.   Annual Review of Physiology

Dissociation Between Brown Adipose Tissue 18 F-FDG Uptake and Thermogenesis in Uncoupling Protein 1–Deficient Mice

(2017) Mohammed K. Hankir et al.   JOURNAL OF NUCLEAR MEDICINE

Glucose feeds the TCA cycle via circulating lactate

(2017) Sheng Hui et al.   NATURE

Warming the mouse to model human diseases

(2017) Kirthana Ganeshan et al.   Nature Reviews Endocrinology

β 3 -Adrenergically induced glucose uptake in brown adipose tissue is independent of UCP1 presence or activity: Mediation through the mTOR pathway

(2017) Jessica M. Olsen et al.   Molecular Metabolism

Brown Adipose Reporting Criteria in Imaging STudies (BARCIST 1.0): Recommendations for Standardized FDG-PET/CT Experiments in Humans

(2016) Kong Y. Chen et al.   Cell Metabolism

mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue

(2016) V. Albert et al.   EMBO Molecular Medicine

Endocannabinoid regulation in white and brown adipose tissue following thermogenic activation

(2016) Lucia M. Krott et al.   JOURNAL OF LIPID RESEARCH

A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance

(2016) Cholsoon Jang et al.   NATURE MEDICINE

A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat

(2015) Lawrence Kazak et al.   CELL

Brown adipose tissue: physiological function and evolutionary significance

(2015) R. Oelkrug et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

Adipose Fatty Acid Oxidation Is Required for Thermogenesis and Potentiates Oxidative Stress-Induced Inflammation

(2015) Jieun Lee et al.   Cell Reports

Glucose uptake in brown fat cells is dependent on mTOR complex 2–promoted GLUT1 translocation

(2014) Jessica M. Olsen et al.   JOURNAL OF CELL BIOLOGY

Contributions of white and brown adipose tissues and skeletal muscles to acute cold-induced metabolic responses in healthy men

(2014) Denis P. Blondin et al.   JOURNAL OF PHYSIOLOGY-LONDON

Brown fat fuel utilization and thermogenesis

(2014) Kristy L. Townsend et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The Endocannabinoid System in Energy Homeostasis and the Etiopathology of Metabolic Disorders

(2013) Cristoforo Silvestri et al.   Cell Metabolism

Effect of short-term cold exposure on skeletal muscle protein breakdown in rats

(2013) L. H. Manfredi et al.   JOURNAL OF APPLIED PHYSIOLOGY

Recruited brown adipose tissue as an antiobesity agent in humans

(2013) Takeshi Yoneshiro et al.   JOURNAL OF CLINICAL INVESTIGATION

Cold acclimation recruits human brown fat and increases nonshivering thermogenesis

(2013) Anouk A.J.J. van der Lans et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanism of Fatty-Acid-Dependent UCP1 Uncoupling in Brown Fat Mitochondria

(2012) Andriy Fedorenko et al.   CELL

Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans

(2012) Véronique Ouellet et al.   JOURNAL OF CLINICAL INVESTIGATION

Different Metabolic Responses of Human Brown Adipose Tissue to Activation by Cold and Insulin

(2011) Janne Orava et al.   Cell Metabolism

Brown fat as a therapy for obesity and diabetes

(2011) Aaron M Cypess et al.   Current Opinion in Endocrinology Diabetes and Obesity

Adipose Acyl-CoA Synthetase-1 Directs Fatty Acids toward β-Oxidation and Is Required for Cold Thermogenesis

(2010) Jessica M. Ellis et al.   Cell Metabolism

CB1 Signaling in Forebrain and Sympathetic Neurons Is a Key Determinant of Endocannabinoid Actions on Energy Balance

(2010) Carmelo Quarta et al.   Cell Metabolism

High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity

(2009) M. Saito et al.   DIABETES

Functional Brown Adipose Tissue in Healthy Adults

(2009) Kirsi A. Virtanen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efeitos do estresse pelo frio sobre o tamanho nuclear do cardiomiócito em ratos: avaliação por microscopia de luz

(2009) Adriano Meneghini et al.   Revista Brasileira de Cirurgia Cardiovascular