Age-dependent effects of Igf2bp2 on gene regulation, function, and aging of hematopoietic stem cells in mice

A comprehensive transcriptome signature of murine hematopoietic stem cell aging

(2021) Arthur Flohr Svendsen et al.   BLOOD

Differential m6A RNA landscapes across hematopoiesis reveal a role for IGF2BP2 in preserving hematopoietic stem cell function

(2021) Rong Yin et al.   Cell Stem Cell

Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging

(2019) Hanzhi Luo et al.   Cell Reports

The long non-coding RNA Meg3 is dispensable for hematopoietic stem cells

(2019) Pia Sommerkamp et al.   Scientific Reports

Adaptive endoplasmic reticulum stress signalling via IRE1α–XBP1 preserves self-renewal of haematopoietic and pre-leukaemic stem cells

(2019) Lu Liu et al.   NATURE CELL BIOLOGY

MLLT3 governs human haematopoietic stem-cell self-renewal and engraftment

(2019) Vincenzo Calvanese et al.   NATURE

Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment

(2018) Ryo Yamamoto et al.   Cell Stem Cell

The Roles of Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 in Cancer and Cancer Stem Cells

(2018) Junguo Cao et al.   Stem Cells International

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency

(2016) Jin Zhang et al.   Cell Stem Cell

Proliferation, survival and metabolism: the role of PI3K/AKT/mTOR signalling in pluripotency and cell fate determination

(2016) Jason S. L. Yu et al.   DEVELOPMENT

Schlafen2 is a critical regulator of adult hematopoietic stem cells

(2016) Sarah Warsi et al.   EXPERIMENTAL HEMATOLOGY

The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs

(2016) Robert A.J. Signer et al.   GENES & DEVELOPMENT

The Long Non-coding RNA HIF1A-AS2 Facilitates the Maintenance of Mesenchymal Glioblastoma Stem-like Cells in Hypoxic Niches

(2016) Marco Mineo et al.   Cell Reports

Imp2 regulates GBM progression by activating IGF2/PI3K/Akt pathway

(2015) Qingchun Mu et al.   CANCER BIOLOGY & THERAPY

IGF2BP2/IMP2-Deficient Mice Resist Obesity through Enhanced Translation of Ucp1 mRNA and Other mRNAs Encoding Mitochondrial Proteins

(2015) Ning Dai et al.   Cell Metabolism

Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions

(2015) Eric M. Pietras et al.   Cell Stem Cell

Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors

(2015) Simon Haas et al.   Cell Stem Cell

A Long Non-coding RNA, LncMyoD, Regulates Skeletal Muscle Differentiation by Blocking IMP2-Mediated mRNA Translation

(2015) Chenguang Gong et al.   DEVELOPMENTAL CELL

An MTCH2 pathway repressing mitochondria metabolism regulates haematopoietic stem cell fate

(2015) Maria Maryanovich et al.   Nature Communications

Identification of Regulatory Networks in HSCs and Their Immediate Progeny via Integrated Proteome, Transcriptome, and DNA Methylome Analysis

(2014) Nina Cabezas-Wallscheid et al.   Cell Stem Cell

Haematopoietic stem cells require a highly regulated protein synthesis rate

(2014) Robert A. J. Signer et al.   NATURE

CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age

(2013) C. Gekas et al.   BLOOD

Lin28: Primal Regulator of Growth and Metabolism in Stem Cells

(2013) Ng Shyh-Chang et al.   Cell Stem Cell

Stem cell metabolism in tissue development and aging

(2013) N. Shyh-Chang et al.   DEVELOPMENT

Maternal imprinting at the H19–Igf2 locus maintains adult haematopoietic stem cell quiescence

(2013) Aparna Venkatraman et al.   NATURE

Linking HSCs to their youth

(2013) Eric M. Pietras et al.   NATURE CELL BIOLOGY

The Lin28b–let-7–Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells

(2013) Michael R. Copley et al.   NATURE CELL BIOLOGY

A novel role of BMP4 in adult hematopoietic stem and progenitor cell homing via Smad independent regulation of integrin- 4 expression

(2012) S. Khurana et al.   BLOOD

Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?

(2012) Jessica L. Bell et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

An HMGA2-IGF2BP2 Axis Regulates Myoblast Proliferation and Myogenesis

(2012) Zhizhong Li et al.   DEVELOPMENTAL CELL

Oncomir miR-125b regulates hematopoiesis by targeting the gene Lin28A

(2012) A. A. Chaudhuri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lin28b Reprograms Adult Bone Marrow Hematopoietic Progenitors to Mediate Fetal-Like Lymphopoiesis

(2012) Joan Yuan et al.   SCIENCE

The Lin28/let-7 Axis Regulates Glucose Metabolism

(2011) Hao Zhu et al.   CELL

p57 Is Required for Quiescence and Maintenance of Adult Hematopoietic Stem Cells

(2011) Akinobu Matsumoto et al.   Cell Stem Cell

Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age

(2011) W. W. Pang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment

(2010) Yohei Morita et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

(2010) I. Beerman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells

(2009) C. Chen et al.   Science Signaling

TSC–mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

(2008) Chong Chen et al.   JOURNAL OF EXPERIMENTAL MEDICINE