Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging

Published 2019 View Full Article

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Title
Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging
Authors
Keywords
SIRT2, SIRT3, SIRT7, mitochondrial UPR, oxidative stress, hematopoietic stem cell, aging, clonal hematopoiesis, NLRP3, inflammasome
Journal
Cell Reports
Volume 26, Issue 4, Pages 945-954.e4
Publisher
Elsevier BV
Online
2019-01-24
DOI
10.1016/j.celrep.2018.12.101

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