Bioorthogonal PEGylation Prolongs the Elimination Half-Life of N-TIMP2 While Retaining MMP Inhibition

Matrix metalloproteinases inhibitors in idiopathic pulmonary fibrosis: Medicinal chemistry perspectives

(2021) Lin Yue et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Genetic Code Expansion Enables Site-Specific PEGylation of a Human Growth Hormone Receptor Antagonist through Click Chemistry

(2020) KYLE TAMSHEN et al.   BIOCONJUGATE CHEMISTRY

Site-Specific Bioconjugation Approaches for Enhanced Delivery of Protein Therapeutics and Protein Drug Carriers

(2020) Rachel M. Lieser et al.   BIOCONJUGATE CHEMISTRY

Site-Specific Immuno-PET Tracer to Image PD-L1

(2019) Haley L. Wissler et al.   MOLECULAR PHARMACEUTICS

Cellular localization of cytochrome bd in cyanobacteria using genetic code expansion

(2019) Mor Cohen et al.   BIOTECHNOLOGY AND BIOENGINEERING

Targeting the MMP-14/MMP-2/integrin αvβ3 axis with multispecific N-TIMP2-based antagonists for cancer therapy

(2018) Gal Yosef et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small Unnatural Amino Acid Carried Raman Tag for Molecular Imaging of Genetically Targeted Proteins

(2018) Jing Zhang et al.   Journal of Physical Chemistry Letters

Live Cell Imaging of Bioorthogonally Labelled Proteins Generated With a Single Pyrrolysine tRNA Gene

(2018) Noa Aloush et al.   Scientific Reports

Development of High Affinity and High Specificity Inhibitors of Matrix Metalloproteinase 14 through Computational Design and Directed Evolution

(2017) Valeria Arkadash et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Precise and combinatorial PEGylation generates a low-immunogenic and stable form of human growth hormone

(2017) Ling Wu et al.   JOURNAL OF CONTROLLED RELEASE

Expanding and reprogramming the genetic code

(2017) Jason W. Chin   NATURE

A semi-synthetic organism that stores and retrieves increased genetic information

(2017) Yorke Zhang et al.   NATURE

In vitro suppression of two different stop codons

(2016) Eden Ozer et al.   BIOTECHNOLOGY AND BIOENGINEERING

How PEGylation influences protein conformational stability

(2016) Paul B Lawrence et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Pyrrolysyl-tRNA synthetase: An ordinary enzyme but an outstanding genetic code expansion tool

(2014) Wei Wan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Production of Site-Specific Antibody–Drug Conjugates Using Optimized Non-Natural Amino Acids in a Cell-Free Expression System

(2014) Erik S. Zimmerman et al.   BIOCONJUGATE CHEMISTRY

Cellular Incorporation of Unnatural Amino Acids and Bioorthogonal Labeling of Proteins

(2014) Kathrin Lang et al.   CHEMICAL REVIEWS

Criteria for Selecting PEGylation Sites on Proteins for Higher Thermodynamic and Proteolytic Stability

(2014) Paul B. Lawrence et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Affinity- and Specificity-Enhancing Mutations Are Frequent in Multispecific Interactions between TIMP2 and MMPs

(2014) Oz Sharabi et al.   PLoS One

Imbalance between MMP-2, 9 and TIMP-1 promote the invasion and metastasis of renal cell carcinoma via SKP2 signaling pathways

(2014) Hongsheng Lu et al.   TUMOR BIOLOGY

Increasing the Antitumor Effect of an EpCAM-Targeting Fusion Toxin by Facile Click PEGylation

(2013) M. Simon et al.   MOLECULAR CANCER THERAPEUTICS

Development of Copper-Catalyzed Azide–Alkyne Cycloaddition for Increased in Vivo Efficacy of Interferon β-1b by Site-Specific PEGylation

(2012) Natalie W. Nairn et al.   BIOCONJUGATE CHEMISTRY

PEGylation Extends Circulation Half-Life While Preserving In Vitro and In Vivo Activity of Tissue Inhibitor of Metalloproteinases-1 (TIMP-1)

(2012) Jyotica Batra et al.   PLoS One

Engineering antibodies and proteins for molecular in vivo imaging

(2011) Tina Romer et al.   CURRENT OPINION IN BIOTECHNOLOGY

Site-Specific Coupling and Sterically Controlled Formation of Multimeric Antibody Fab Fragments with Unnatural Amino Acids

(2011) Benjamin M. Hutchins et al.   JOURNAL OF MOLECULAR BIOLOGY

Worldwide experience with biosimilar development

(2011) Mark McCamish et al.   mAbs

Antibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potential

(2011) Netta Sela-Passwell et al.   NATURE MEDICINE

Tissue inhibitors of metalloproteinases

(2011) Gillian Murphy   GENOME BIOLOGY

Coordinate action of membrane-type matrix metalloproteinase-1 (MT1-MMP) and MMP-2 enhances pericellular proteolysis and invasion

(2010) Hiroshi Sato et al.   CANCER SCIENCE

PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel

(2010) Yong Zhang et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

The Chemokine Receptor CXCR4 and the Metalloproteinase MT1-MMP Are Mutually Required during Melanoma Metastasis to Lungs

(2009) Rubén A. Bartolomé et al.   AMERICAN JOURNAL OF PATHOLOGY

Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis

(2009) Laetitia Devy et al.   CANCER RESEARCH

MMP-14 can serve as a prognostic marker in patients with supraglottic cancer

(2009) Huiyan Zhang et al.   EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY

An Enhanced System for Unnatural Amino Acid Mutagenesis in E. coli

(2009) Travis S. Young et al.   JOURNAL OF MOLECULAR BIOLOGY

The Impact of PEGylation on Biological Therapies

(2008) Francesco M Veronese et al.   BIODRUGS

Expression of membrane type 1 matrix metalloproteinase (MMP-14) in epithelial ovarian cancer: High level expression in clear cell carcinoma

(2008) Brian P. Adley et al.   GYNECOLOGIC ONCOLOGY

The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin

(2008) Hilary A. Kenny et al.   JOURNAL OF CLINICAL INVESTIGATION

Progress in matrix metalloproteinase research

(2008) G MURPHY et al.   MOLECULAR ASPECTS OF MEDICINE