Affinity- and Specificity-Enhancing Mutations Are Frequent in Multispecific Interactions between TIMP2 and MMPs

Mapping of the Binding Landscape for a Picomolar Protein-Protein Complex through Computation and Experiment

(2014) Yonatan Aizner et al.   STRUCTURE

Predicting affinity- and specificity-enhancing mutations at protein–protein interfaces

(2013) Oz Sharabi et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Matrix Metalloproteinase-10/TIMP-2 Structure and Analyses Define Conserved Core Interactions and Diverse Exosite Interactions in MMP/TIMP Complexes

(2013) Jyotica Batra et al.   PLoS One

A Strategy for Modulation of Enzymes in the Ubiquitin System

(2013) A. Ernst et al.   SCIENCE

Multispecific Recognition: Mechanism, Evolution, and Design

(2011) Ariel Erijman et al.   BIOCHEMISTRY

Achieving broad molecular insights into dynamic protein interactions by integrated structural–kinetic approaches

(2011) Moran Grossman et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Phage Display of Tissue Inhibitor of Metalloproteinases-2 (TIMP-2)

(2011) Harinath Bahudhanapati et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transfer-PCR (TPCR): A highway for DNA cloning and protein engineering

(2011) Ariel Erijman et al.   JOURNAL OF STRUCTURAL BIOLOGY

Triathlon for energy functions: Who is the winner for design of protein-protein interactions?

(2011) Oz Sharabi et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Tissue inhibitors of metalloproteinases

(2011) Gillian Murphy   GENOME BIOLOGY

The Intrinsic Protein Flexibility of Endogenous Protease Inhibitor TIMP-1 Controls Its Binding Interface and Affects Its Function

(2010) Moran Grossman et al.   BIOCHEMISTRY

The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity

(2010) Keith Brew et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Tradeoff Between Stability and Multispecificity in the Design of Promiscuous Proteins

(2009) Menachem Fromer et al.   PLoS Computational Biology

Activation of Matrix Metalloproteinase-2 (MMP-2) by Membrane Type 1 Matrix Metalloproteinase through an Artificial Receptor for ProMMP-2 Generates Active MMP-2

(2008) Yuki Nishida et al.   CANCER RESEARCH

Structural Determinants of the ADAM Inhibition by TIMP-3: Crystal Structure of the TACE-N-TIMP-3 Complex

(2008) Magdalena Wisniewska et al.   JOURNAL OF MOLECULAR BIOLOGY

Reappraising metalloproteinases in rheumatoid arthritis and osteoarthritis: destruction or repair?

(2008) Gillian Murphy et al.   Nature clinical practice. Rheumatology