Recommendations on dose level selection for repeat dose toxicity studies

The EU chemicals strategy for sustainability: in support of the BfR position

(2021) Frank A. Barile et al.   ARCHIVES OF TOXICOLOGY

The “EU chemicals strategy for sustainability” questions regulatory toxicology as we know it: is it all rooted in sound scientific evidence?

(2021) Matthias Herzler et al.   ARCHIVES OF TOXICOLOGY

Opportunities and challenges related to saturation of toxicokinetic processes: Implications for risk assessment

(2021) Yu-Mei Tan et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Rethinking agrochemical safety assessment: A perspective

(2021) Fiona Sewell et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Use of the kinetically-derived maximum dose concept in selection of top doses for toxicity studies hampers proper hazard assessment and risk management

(2020) Minne B. Heringa et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Regulating human safety: How dose selection in toxicity studies impacts human health hazard assessment and subsequent risk management options

(2020) Marjolijn Woutersen et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

The relationship between internal and external dose: Some general results based on a generic compartmental model

(2020) Wout Slob et al.   TOXICOLOGICAL SCIENCES

Use of the kinetically-derived maximum dose: Opportunities for delivering 3Rs benefits

(2020) Fiona Sewell et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Letter to the editors regarding Heringa et al. (2020)

(2020) Carr J. Smith et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

The current status of exposure-driven approaches for chemical safety assessment: A cross-sector perspective

(2017) Fiona Sewell et al.   TOXICOLOGY

A Good Death? Report of the Second Newcastle Meeting on Laboratory Animal Euthanasia

(2016) Penny Hawkins et al.   Animals

A global initiative to refine acute inhalation studies through the use of ‘evident toxicity’ as an endpoint: Towards adoption of the fixed concentration procedure

(2015) Fiona Sewell et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Reducing pre-clinical blood volumes for toxicokinetics: toxicologists, pathologists and bioanalysts unite

(2014) Kathryn Chapman et al.   Bioanalysis

A global pharmaceutical company initiative: An evidence-based approach to define the upper limit of body weight loss in short term toxicity studies

(2013) Kathryn Chapman et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

ILSI/HESI maternal toxicity workshop summary: maternal toxicity and its impact on study design and data interpretation

(2010) Bruce K. Beyer et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY