Reducing pre-clinical blood volumes for toxicokinetics: toxicologists, pathologists and bioanalysts unite

Overcoming the barriers to the uptake of nonclinical microsampling in regulatory safety studies

(2014) Kathryn Chapman et al.   DRUG DISCOVERY TODAY

Assessment of toxicological effects of blood microsampling in the vehicle dosed adult rat

(2014) Nicola Powles-Glover et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Assessment of haematological and clinical pathology effects of blood microsampling in suckling and weaned juvenile rats

(2014) Nicola Powles-Glover et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

European Bioanalysis Forum continued plans to support liquid microsampling

(2014) Philip Timmerman et al.   Bioanalysis

A novel approach to capillary plasma microsampling for quantitative bioanalysis

(2013) Chester L Bowen et al.   Bioanalysis

Assessment of diurnal systemic dose of agrochemicals in regulatory toxicity testing – An integrated approach without additional animal use

(2012) Shakil A. Saghir et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Validation of a bioanalytical method using capillary microsampling of 8 µl plasma samples: application to a toxicokinetic study in mice

(2012) Ove Jonsson et al.   Bioanalysis

Opportunities to minimise animal use in pharmaceutical regulatory general toxicology: A cross-company review

(2011) Susan S. Sparrow et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Use of toxicokinetics to support chemical evaluation: Informing high dose selection and study interpretation

(2011) Stuart Creton et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Dried blood spot sampling: practical considerations and recommendation for use with preclinical studies

(2011) Josephine EC Burnett   Bioanalysis

Application of toxicokinetics to improve chemical risk assessment: Implications for the use of animals

(2009) Stuart Creton et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY