Milk thistle and co-enzyme Q10 fortified diets lessen the nickel chloride-induced neurotoxic and neurobehavioral impairments in Oreochromis niloticus via regulating the oxidative stress response, acetylcholinesterase activity, and brain nickel content

Coenzyme Q10 protected against arsenite and enhanced the capacity of 2,3-dimercaptosuccinic acid to ameliorate arsenite-induced toxicity in mice

(2021) Victoria K. Mwaeni et al.   BMC Pharmacology & Toxicology

Heavy metals affecting Neotropical freshwater fish: A review of the last 10 years of research

(2021) Alessandro Loureiro Paschoalini et al.   AQUATIC TOXICOLOGY

A novel supplement with yeast β-glucan, prebiotic, minerals and Silybum marianum synergistically modulates metabolic and inflammatory pathways and improves steatosis in obese mice

(2021) Victor Abou Nehmi et al.   Journal of Integrative Medicine-JIM

The single or combined Silybum marianum and co-enzyme Q10 role in alleviating fluoride-induced impaired growth, immune suppression, oxidative stress, histological alterations, and reduced resistance to Aeromonas sobria in African catfish (Clarias gariepinus)

(2021) Walaa El-Houseiny et al.   AQUACULTURE

Environmental risk of nickel in aquatic Arctic ecosystems

(2021) Patrick T. Gauthier et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Selective breeding trait preferences for farmed tilapia among low-income women and men consumers in Egypt; Implications for pro-poor and gender-responsive fish breeding programmes

(2020) Seamus Murphy et al.   AQUACULTURE

Melamine and curcumin enriched diets modulate the haemato-immune response, growth performance, oxidative stress, disease resistance, and cytokine production in oreochromis niloticus

(2020) Yasmina M. Abd El-Hakim et al.   AQUATIC TOXICOLOGY

Assessing the effectiveness of CoQ10 dietary supplementation on growth performance, digestive enzymes, blood health, immune response, and oxidative-related genes expression of Nile tilapia (Oreochromis niloticus)

(2020) Mohammed F. El Basuini et al.   FISH & SHELLFISH IMMUNOLOGY

Coenzyme Q10 Activates the Antioxidant Machinery and Inhibits the Inflammatory and Apoptotic Cascades Against Lead Acetate-Induced Renal Injury in Rats

(2020) Wafa A. AL-Megrin et al.   Frontiers in Physiology

Natural and anthropogenic sources of lead, zinc, and nickel in sediments of Lake Izabal, Guatemala

(2020) Elisandra Hernández et al.   Journal of Environmental Sciences-China

Silymarin in Combination with Vitamin C, Vitamin E, Coenzyme Q10 and Selenomethionine to Improve Liver Enzymes and Blood Lipid Profile in NAFLD Patients

(2020) Annalisa Curcio et al.   Medicina-Lithuania

The influence of dietary coenzyme Q10 and vitamin C on the growth rate, immunity, oxidative-related genes, and the resistance against Streptococcus agalactiae of Nile tilapia (Oreochromis niloticus)

(2020) Mohammed F. El Basuini et al.   AQUACULTURE

Neurobehavioral and immune-toxic impairments induced by organic methyl mercury dietary exposure in Nile tilapia Oreochromis niloticus

(2020) Ehsan H. Abu Zeid et al.   AQUATIC TOXICOLOGY

The food plant Silybum marianum (L.) Gaertn.: Phytochemistry, Ethnopharmacology and clinical evidence

(2020) Ilias Marmouzi et al.   JOURNAL OF ETHNOPHARMACOLOGY

Deep neural network analysis - a paradigm shift for histological examination of health and welfare of farmed fish

(2020) Lene Sveen et al.   AQUACULTURE

Glycyrrhizic acid and silymarin alleviate the neurotoxic effects of aluminum in rats challenged with fructose-induced insulin resistance: possible role of toll-like receptor 4 pathway

(2019) Noura M. Ali et al.   DRUG AND CHEMICAL TOXICOLOGY

Cytotoxic, hepatoprotective and antioxidant activities of Silybum marianum variety albiflorum growing in Egypt

(2019) Hayam S. Ahmed et al.   NATURAL PRODUCT RESEARCH

Ameliorative effects of Moringa oleifera seeds and leaves on chlorpyrifos-induced growth retardation, immune suppression, oxidative stress, and DNA damage in Oreochromis niloticus

(2019) Rowida E. Ibrahim et al.   AQUACULTURE

Palliative effects of zinc sulfate against the immunosuppressive, hepato- and nephrotoxic impacts of nonylphenol in Nile tilapia (Oreochromis niloticus)

(2019) Wafaa A.M. Mohamed et al.   AQUACULTURE

The palliative role of Eruca sativa leaves dietary supplementation against oxidative stress, immunosuppression, and growth retardation in temperature-stressed Oreochromis niloticus

(2019) Rowida E. Ibrahim et al.   JOURNAL OF THERMAL BIOLOGY

Effect of Silybum marianum seeds as a feed additive on growth performance, serum biochemical indices, antioxidant status, and gene expression of Nile tilapia, Oreochromis niloticus (L.) fingerlings

(2019) Mohamed S. Hassaan et al.   AQUACULTURE

The Neuroprotective Role of Coenzyme Q10 Against Lead Acetate-Induced Neurotoxicity Is Mediated by Antioxidant, Anti-Inflammatory and Anti-Apoptotic Activities

(2019) Al Omar S. Yousef et al.   International Journal of Environmental Research and Public Health

Reversal effects of some safe dietary supplements on lead contaminated diet induced impaired growth and associated parameters in Nile tilapia

(2019) Mohamed Salah Ayyat et al.   AQUACULTURE

Effect of hexavalent chromium exposure on the liver and kidney tissues related to the expression of CYP450 and GST genes of Oreochromis niloticus fish: Role of curcumin supplemented diet

(2019) Amany Abdel-Rahman Mohamed et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Arsenic-induced oxidative stress, cholinesterase activity in the brain of Swiss albino mice, and its amelioration by antioxidants Vitamin E and Coenzyme Q10

(2018) Anupama Sharma et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

The mechanisms of nickel toxicity in aquatic environments: An adverse outcome pathway analysis

(2017) Kevin V. Brix et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Molecular mechanisms of nickel induced neurotoxicity and chemoprevention

(2017) Xin Song et al.   TOXICOLOGY

Investigating the mechanisms of Ni uptake and sub-lethal toxicity in the Atlantic killifish Fundulus heteroclitus in relation to salinity

(2016) Tamzin A. Blewett et al.   ENVIRONMENTAL POLLUTION

Mechanisms of Nickel Toxicity in the Highly Sensitive Embryos of the Sea Urchin Evechinus chloroticus, and the Modifying Effects of Natural Organic Matter

(2016) Tamzin A. Blewett et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Silybin content and overexpression of chalcone synthase genes in Silybum marianum L. plants under abiotic elicitation

(2016) Hoda A.S. El-Garhy et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Low salinity enhances NI-mediated oxidative stress and sub-lethal toxicity to the green shore crab (Carcinus maenas)

(2015) Tamzin A. Blewett et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Mixtures of benzo(a)pyrene, dichlorodiphenyltrichloroethane and tributyltin are more toxic to neotropical fish Rhamdia quelen than isolated exposures

(2015) Heloísa H.P. Oliveira et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Characterization of Synergistic Embryotoxicity of Nickel and Buprofezin in Zebrafish

(2015) Tingting Ku et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Neurotoxic effects of nickel chloride in the rainbow trout brain: Assessment of c-Fos activity, antioxidant responses, acetylcholinesterase activity, and histopathological changes

(2015) Ahmet Topal et al.   FISH PHYSIOLOGY AND BIOCHEMISTRY

Waterborne cadmium and nickel impact oxidative stress responses and retinoid metabolism in yellow perch

(2014) Michel A. Defo et al.   AQUATIC TOXICOLOGY

Salinity-Dependent Nickel Accumulation and Oxidative Stress Responses in the Euryhaline Killifish (Fundulus heteroclitus)

(2014) Tamzin A. Blewett et al.   ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Critical body residues, Michaelis–Menten analysis of bioaccumulation, lethality and behaviour as endpoints of waterborne Ni toxicity in two teleosts

(2014) Erin M. Leonard et al.   ECOTOXICOLOGY

Whole adult organism transcriptional profiling of acute metal exposures in male Zebrafish

(2014) Naissan Hussainzada et al.   BMC Pharmacology & Toxicology

How does exposure to nickel and cadmium affect the transcriptome of yellow perch (Perca flavescens) – Results from a 1000 candidate-gene microarray

(2013) Bérénice Bougas et al.   AQUATIC TOXICOLOGY

Nickel-induced oxidative stress and apoptosis in Carassius auratus liver by JNK pathway

(2013) Gui-Hong Zheng et al.   AQUATIC TOXICOLOGY

Antioxidant system efficiently protects goldfish gills from Ni2+-induced oxidative stress

(2012) Olga I. Kubrak et al.   CHEMOSPHERE

Nickel induces hyperglycemia and glycogenolysis and affects the antioxidant system in liver and white muscle of goldfish Carassius auratus L.

(2012) Olga I. Kubrak et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Role of Calcium and Mitochondria in MeHg-Mediated Cytotoxicity

(2012) Daniel Roos et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Improvement of brain energy metabolism and cholinergic functions contributes to the beneficial effects of silibinin against streptozotocin induced memory impairment

(2011) Santoshkumar Tota et al.   BEHAVIOURAL BRAIN RESEARCH

Acute toxic effects of pyrene on Pomatoschistus microps (Teleostei, Gobiidae): Mortality, biomarkers and swimming performance

(2011) M. Oliveira et al.   ECOLOGICAL INDICATORS

Effects of long-term silymarin oral supplementation on the blood biochemical profile of rainbow trout (Oncorhynchus mykiss)

(2011) Mahdi Banaee et al.   FISH PHYSIOLOGY AND BIOCHEMISTRY

Behavioural indicators of welfare in farmed fish

(2011) Catarina I. M. Martins et al.   FISH PHYSIOLOGY AND BIOCHEMISTRY

Natural factors to consider when using acetylcholinesterase activity as neurotoxicity biomarker in Young-Of-Year striped bass (Morone saxatilis)

(2010) Eric D. H. Durieux et al.   FISH PHYSIOLOGY AND BIOCHEMISTRY

Functions of coenzyme Q10in inflammation and gene expression

(2009) Constance Schmelzer et al.   BIOFACTORS

Evaluation of the Acute Toxicity of Profenofos and Its Effects on the Behavioral Pattern of Fingerling Common Carp (Cyprinus carpio L., 1758)

(2009) Muhammad Ismail et al.   BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Behavioural and developmental toxicity of chlorpyrifos and nickel chloride to zebrafish (Danio rerio) embryos and larvae

(2009) Cornelia Kienle et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Interference of nickel with copper and iron homeostasis contributes to metal toxicity symptoms in the nickel hyperaccumulator plantAlyssum inflatum

(2009) Rasoul Ghasemi et al.   NEW PHYTOLOGIST

Influence of Nickel Chloride, Chlorpyrifos, and Imidacloprid in Combination with Different Temperatures on the Embryogenesis of the Zebrafish Danio rerio

(2008) Volker Scheil et al.   ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

In vitroantioxidant activity of silymarin

(2008) Ekrem KÖksal et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Ni2+Block of CaV3.1 (α1G) T-type Calcium Channels

(2008) Carlos A. Obejero-Paz et al.   JOURNAL OF GENERAL PHYSIOLOGY

Assessment of drug–drug interaction for silymarin

(2008) Johannes Doehmer et al.   TOXICOLOGY IN VITRO