S ‐adenosyl‐L‐homocysteine extends lifespan through methionine restriction effects

Enhancing lifespan of budding yeast by pharmacological lowering of amino acid pools

(2021) Nathaniel L. Hepowit et al.   Aging-US

Regulation of the one carbon folate cycle as a shared metabolic signature of longevity

(2021) Andrea Annibal et al.   Nature Communications

Effects of dietary methionine and cysteine restriction on plasma biomarkers, serum fibroblast growth factor 21, and adipose tissue gene expression in women with overweight or obesity: a double-blind randomized controlled pilot study

(2020) Thomas Olsen et al.   Journal of Translational Medicine

A novel gene-diet interaction promotes organismal lifespan and host protection during infection via the mitochondrial UPR

(2020) Mustafi Raisa Amin et al.   PLoS Genetics

Dietary methionine influences therapy in mouse cancer models and alters human metabolism

(2019) Xia Gao et al.   NATURE

Methionine metabolism and methyltransferases in the regulation of aging and lifespan extension across species

(2019) Andrey A. Parkhitko et al.   AGING CELL

Extension of Cellular Lifespan by Methionine Restriction Involves Alterations in Central Carbon Metabolism and Is Mitophagy-Dependent

(2019) Jason D. Plummer et al.   Frontiers in Cell and Developmental Biology

Disease prevention and delayed aging by dietary sulfur amino acid restriction: translational implications

(2018) Zhen Dong et al.   Annals of the New York Academy of Sciences

Pleiotropic responses to methionine restriction

(2017) Gene P. Ables et al.   EXPERIMENTAL GERONTOLOGY

StimulatingS-adenosyl-l-methionine synthesis extends lifespan via activation of AMPK

(2016) Takafumi Ogawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhancing S-adenosyl-methionine catabolism extends Drosophila lifespan

(2015) Fumiaki Obata et al.   Nature Communications

Innate Host Defense Requires TFEB-Mediated Transcription of Cytoprotective and Antimicrobial Genes

(2014) Orane Visvikis et al.   IMMUNITY

Making new contacts: the mTOR network in metabolism and signalling crosstalk

(2014) Mitsugu Shimobayashi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Methionine Restriction Activates the Retrograde Response and Confers Both Stress Tolerance and Lifespan Extension to Yeast, Mouse and Human Cells

(2014) Jay E. Johnson et al.   PLoS One

Lifespan Extension by Methionine Restriction Requires Autophagy-Dependent Vacuolar Acidification

(2014) Christoph Ruckenstuhl et al.   PLoS Genetics

Independent and Additive Effects of Glutamic Acid and Methionine on Yeast Longevity

(2013) Ziyun Wu et al.   PLoS One

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

(2012) Carmine Settembre et al.   EMBO JOURNAL

GFP-Atg8 protease protection as a tool to monitor autophagosome biogenesis

(2011) Usha Nair et al.   Autophagy

A Conserved SREBP-1/Phosphatidylcholine Feedback Circuit Regulates Lipogenesis in Metazoans

(2011) Amy K. Walker et al.   CELL

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Manipulation of Behavioral Decline in Caenorhabditis elegans with the Rag GTPase raga-1

(2010) Matthew A. Schreiber et al.   PLoS Genetics

The low-methionine content of vegan diets may make methionine restriction feasible as a life extension strategy

(2008) Mark F. McCarty et al.   MEDICAL HYPOTHESES