Mitochondria-targeted Antioxidants Protect Pancreatic β-cells against Oxidative Stress and Improve Insulin Secretion in Glucotoxicity and Glucolipotoxicity

Mitochondria-Targeted Antioxidants in the Treatment of Disease

(2010) Robin A.J. Smith et al.   Annals of the New York Academy of Sciences

Animal and human studies with the mitochondria-targeted antioxidant MitoQ

(2010) Robin A.J. Smith et al.   Annals of the New York Academy of Sciences

Prevention of diabetic nephropathy in Ins2+/−AkitaJmice by the mitochondria-targeted therapy MitoQ

(2010) Balu K. Chacko et al.   BIOCHEMICAL JOURNAL

Proto-oncogenic H-Ras, K-Ras and N-Ras are involved in muscle differentiation via phosphatidylinositol 3-kinase

(2010) Jisun Lee et al.   CELL RESEARCH

Carbonyl reductase 1 protects pancreatic β-cells against oxidative stress-induced apoptosis in glucotoxicity and glucolipotoxicity

(2010) M.A. Rashid et al.   FREE RADICAL BIOLOGY AND MEDICINE

The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients

(2010) Edward J. Gane et al.   LIVER INTERNATIONAL

Effects of tempol and redox-cycling nitroxides in models of oxidative stress

(2010) Christopher S. Wilcox   PHARMACOLOGY & THERAPEUTICS

Mammalian Mitochondrial Complex I: Biogenesis, Regulation, and Reactive Oxygen Species Generation

(2009) Werner J.H. Koopman et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial Dysfunction in Diabetes: From Molecular Mechanisms to Functional Significance and Therapeutic Opportunities

(2009) William I. Sivitz et al.   ANTIOXIDANTS & REDOX SIGNALING

Sodium selenite induces apoptosis by ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction in human acute promyelocytic leukemia NB4 cells

(2009) Liying Guan et al.   APOPTOSIS

Mitochondria-Targeted Antioxidant MitoQ 10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy

(2009) Delyth Graham et al.   HYPERTENSION

Reactive Oxygen Species Facilitate Adipocyte Differentiation by Accelerating Mitotic Clonal Expansion

(2009) Haemi Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Liver X Receptor Agonists Augment Human Islet Function through Activation of Anaplerotic Pathways and Glycerolipid/Free Fatty Acid Cycling

(2009) Takeshi Ogihara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diet-induced Renal Changes in Zucker Rats Are Ameliorated by the Superoxide Dismutase Mimetic TEMPOL

(2009) Philip J. Ebenezer et al.   Obesity

Endothelial cell respiration is affected by the oxygen tension during shear exposure: role of mitochondrial peroxynitrite

(2008) Charles I. Jones et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Nox4 Acts as a Switch Between Differentiation and Proliferation in Preadipocytes

(2008) Katrin Schröder et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Oxidative stress induced lipid accumulation via SREBP1c activation in HepG2 cells

(2008) Mika Sekiya et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Fatty Acid Synthase Gene Is Up-regulated by Hypoxia via Activation of Akt and Sterol Regulatory Element Binding Protein-1

(2008) E. Furuta et al.   CANCER RESEARCH

Glucolipotoxicity: Fuel Excess and β-Cell Dysfunction

(2008) Vincent Poitout et al.   ENDOCRINE REVIEWS

A mitochondria-targeted nitroxide is reduced to its hydroxylamine by ubiquinol in mitochondria

(2008) Jan Trnka et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antioxidant properties of MitoTEMPOL and its hydroxylamine

(2008) Jan Trnka et al.   FREE RADICAL RESEARCH

Overexpression of Mitochondrial Methionine Sulfoxide Reductase B2 Protects Leukemia Cells from Oxidative Stress-induced Cell Death and Protein Damage

(2008) Filipe Cabreiro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpressed cyclophilin B suppresses apoptosis associated with ROS and Ca2+ homeostasis after ER stress

(2008) J. Kim et al.   JOURNAL OF CELL SCIENCE

Is Antioxidant Potential of the Mitochondrial Targeted Ubiquinone Derivative MitoQ Conserved in Cells Lacking mtDNA?

(2007) Chao Lu et al.   ANTIOXIDANTS & REDOX SIGNALING