Cancer Type Classification in Liquid Biopsies Based on Sparse Mutational Profiles Enabled through Data Augmentation and Integration

Integrative statistical analyses of multiple liquid biopsy analytes in metastatic breast cancer

(2021) Corinna Keup et al.   Genome Medicine

Fragmentation patterns and personalized sequencing of cell‐free DNA in urine and plasma of glioma patients

(2021) Florent Mouliere et al.   EMBO Molecular Medicine

Pan-cancer analysis of whole genomes

(2020)   NATURE

A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns

(2020) Wei Jiao et al.   Nature Communications

Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring

(2020) Asaf Zviran et al.   NATURE MEDICINE

Targeted Therapy Against the Cell of Origin in Cutaneous Squamous Cell Carcinoma

(2019) Stephen J. Goldie et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Genome-wide cell-free DNA fragmentation in patients with cancer

(2019) Stephen Cristiano et al.   NATURE

Passenger mutations accurately classify human tumors

(2019) Marina Salvadores et al.   PLoS Computational Biology

Liquid biopsy-based comprehensive gene mutation profiling for gynecological cancer using CAncer Personalized Profiling by deep Sequencing

(2019) Naoyuki Iwahashi et al.   Scientific Reports

High-intensity sequencing reveals the sources of plasma circulating cell-free DNA variants

(2019) Pedram Razavi et al.   NATURE MEDICINE

Development and validation of a targeted gene sequencing panel for application to disparate cancers

(2019) Mark J. McCabe et al.   Scientific Reports

Concordance of Genomic Alterations by Next-Generation Sequencing in Tumor Tissue versus Cell-Free DNA in Stage I–IV Non–Small Cell Lung Cancer

(2019) John Jiang et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Comprehensive Characterization of Cancer Driver Genes and Mutations

(2018) Matthew H. Bailey et al.   CELL

Detection and localization of surgically resectable cancers with a multi-analyte blood test

(2018) Joshua D. Cohen et al.   SCIENCE

Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors

(2017) Viktor A. Adalsteinsson et al.   Nature Communications

Detection of somatic variants and EGFR mutations in cell-free DNA from non-small cell lung cancer patients by ultra-deep sequencing using the ion ampliseq cancer hotspot panel and droplet digital polymerase chain reaction

(2017) Jae Sook Sung et al.   Oncotarget

Cell-Free DNA Provides a Good Representation of the Tumor Genome Despite Its Biased Fragmentation Patterns

(2017) Xiangyuan Ma et al.   PLoS One

Cell type-specific properties and environment shape tissue specificity of cancer genes

(2016) Martin H. Schaefer et al.   Scientific Reports

A mini review on cancer of unknown primary site: A clinical puzzle for the oncologists

(2015) Nicholas Pavlidis et al.   Journal of Advanced Research

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

(2014) C. Bettegowda et al.   Science Translational Medicine

Blood-Based Analyses of Cancer: Circulating Tumor Cells and Circulating Tumor DNA

(2014) D. A. Haber et al.   Cancer Discovery

Molecular Diagnosis of the Tissue of Origin in Cancer of Unknown Primary Site: Useful in Patient Management

(2013) F. Anthony Greco   CURRENT TREATMENT OPTIONS IN ONCOLOGY

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

A Landscape of Driver Mutations in Melanoma

(2012) Eran Hodis et al.   CELL

Detection of Tumor PIK3CA Status in Metastatic Breast Cancer Using Peripheral Blood

(2012) M. J. Higgins et al.   CLINICAL CANCER RESEARCH

Use of Research Biopsies in Clinical Trials: Are Risks and Benefits Adequately Discussed?

(2012) Michael J. Overman et al.   JOURNAL OF CLINICAL ONCOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

BCL2 mutations in diffuse large B-cell lymphoma

(2011) J M Schuetz et al.   LEUKEMIA