Passenger mutations accurately classify human tumors

Cancer subtype identification using somatic mutation data

(2018) Marieke Lydia Kuijjer et al.   BRITISH JOURNAL OF CANCER

Comprehensive Characterization of Cancer Driver Genes and Mutations

(2018) Matthew H. Bailey et al.   CELL

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

(2018) Katherine A. Hoadley et al.   CELL

Detection and localization of surgically resectable cancers with a multi-analyte blood test

(2018) Joshua D. Cohen et al.   SCIENCE

CADD: predicting the deleteriousness of variants throughout the human genome

(2018) Philipp Rentzsch et al.   NUCLEIC ACIDS RESEARCH

Integrated genomic characterization of oesophageal carcinoma

(2017)   NATURE

Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors

(2017) Viktor A. Adalsteinsson et al.   Nature Communications

AACR Project GENIE: Powering Precision Medicine through an International Consortium

(2017)   Cancer Discovery

A core program of gene expression characterizes cancer metastases

(2017) Franz Hartung et al.   Oncotarget

Assessment of circulating copy number variant detection for cancer screening

(2017) Bhuvan Molparia et al.   PLoS One

A Landscape of Pharmacogenomic Interactions in Cancer

(2016) Francesco Iorio et al.   CELL

Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis

(2016) Sebastian Moran et al.   LANCET ONCOLOGY

Perspective: The precision-oncology illusion

(2016) Vinay Prasad   NATURE

FACETS: allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing

(2016) Ronglai Shen et al.   NUCLEIC ACIDS RESEARCH

COSMIC: somatic cancer genetics at high-resolution

(2016) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Cancers of unknown primary site: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2015) K. Fizazi et al.   ANNALS OF ONCOLOGY

TumorTracer: a method to identify the tissue of origin from the somatic mutations of a tumor specimen

(2015) Andrea Marion Marquard et al.   BMC Medical Genomics

The somatic autosomal mutation matrix in cancer genomes

(2015) Nuri A. Temiz et al.   HUMAN GENETICS

Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF-Mutated Colorectal Cancer

(2015) Scott Kopetz et al.   JOURNAL OF CLINICAL ONCOLOGY

Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial

(2015) Christophe Le Tourneau et al.   LANCET ONCOLOGY

Cancer type-dependent genetic interactions between cancer driver alterations indicate plasticity of epistasis across cell types

(2015) S. Park et al.   Molecular Systems Biology

Differential DNA mismatch repair underlies mutation rate variation across the human genome

(2015) Fran Supek et al.   NATURE

Cell-of-origin chromatin organization shapes the mutational landscape of cancer

(2015) Paz Polak et al.   NATURE

Comprehensive genomic characterization of head and neck squamous cell carcinomas

(2015)   NATURE

The Precision-Recall Plot Is More Informative than the ROC Plot When Evaluating Binary Classifiers on Imbalanced Datasets

(2015) Takaya Saito et al.   PLoS One

Multiplatform Analysis of 12 Cancer Types Reveals Molecular Classification within and across Tissues of Origin

(2014) Katherine A. Hoadley et al.   CELL

Transcription Restores DNA Repair to Heterochromatin, Determining Regional Mutation Rates in Cancer Genomes

(2014) Christina L. Zheng et al.   Cell Reports

The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes

(2013) Tae-Min Kim et al.   CELL

Molecular Diagnosis of the Tissue of Origin in Cancer of Unknown Primary Site: Useful in Patient Management

(2013) F. Anthony Greco   CURRENT TREATMENT OPTIONS IN ONCOLOGY

Blinded Comparator Study of Immunohistochemical Analysis versus a 92-Gene Cancer Classifier in the Diagnosis of the Primary Site in Metastatic Tumors

(2013) Lawrence M. Weiss et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Network-based stratification of tumor mutations

(2013) Matan Hofree et al.   NATURE METHODS

A Landscape of Driver Mutations in Melanoma

(2012) Eran Hodis et al.   CELL

Chromatin organization is a major influence on regional mutation rates in human cancer cells

(2012) Benjamin Schuster-Böckler et al.   NATURE

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Fast Computation and Applications of Genome Mappability

(2012) Thomas Derrien et al.   PLoS One

MicroRNAs accurately identify cancer tissue origin

(2008) Nitzan Rosenfeld et al.   NATURE BIOTECHNOLOGY