Caffeine and EGCG Alleviate High-Trans Fatty Acid and High-Carbohydrate Diet-Induced NASH in Mice: Commonality and Specificity

Management of non-alcoholic fatty liver disease

(2021) Maria Letizia Petroni et al.   BMJ-British Medical Journal

Therapeutic pipeline in nonalcoholic steatohepatitis

(2021) Raj Vuppalanchi et al.   Nature Reviews Gastroenterology & Hepatology

Epigallocatechin-3-Gallate Dampens Non-Alcoholic Fatty Liver by Modulating Liver Function, Lipid Profile and Macrophage Polarization

(2021) Yong Du et al.   Nutrients

Effects of supplementation with main coffee components including caffeine and/or chlorogenic acid on hepatic, metabolic, and inflammatory indices in patients with non-alcoholic fatty liver disease and type 2 diabetes: a randomized, double-blind, placebo-controlled, clinical trial

(2021) Asieh Mansour et al.   Nutrition Journal

Epigallocatechin-3-Gallate Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via Inhibition of Apoptosis and Promotion of Autophagy through the ROS/MAPK Signaling Pathway

(2021) Dongdong Wu et al.   Oxidative Medicine and Cellular Longevity

Geniposide and Chlorogenic Acid Combination Improves Non-Alcoholic Fatty Liver Disease Involving the Potent Suppression of Elevated Hepatic SCD-1

(2021) Cheng Chen et al.   Frontiers in Pharmacology

Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1

(2021) Lin Wang et al.   Cell Metabolism

Obeticholic Acid Impact on Quality of Life in Patients With Nonalcoholic Steatohepatitis: REGENERATE 18-Month Interim Analysis

(2021) Zobair M. Younossi et al.   Clinical Gastroenterology and Hepatology

Effect of Coffee Consumption on Non-Alcoholic Fatty Liver Disease Incidence, Prevalence and Risk of Significant Liver Fibrosis: Systematic Review with Meta-Analysis of Observational Studies

(2021) Maryam Ebadi et al.   Nutrients

Herb-induced liver injury: Systematic review and meta-analysis

(2021) Vinícius Remus Ballotin et al.   World Journal of Clinical Cases

Green Tea and Epigallocatechin Gallate (EGCG) for the Management of Nonalcoholic Fatty Liver Diseases (NAFLD): Insights into the Role of Oxidative Stress and Antioxidant Mechanism

(2021) Guoyi Tang et al.   Antioxidants

Therapeutic landscape for NAFLD in 2020

(2020) Brent A. Neuschwander-Tetri   GASTROENTEROLOGY

CD47 Deficiency in Mice Exacerbates Chronic Fatty Diet-Induced Steatohepatitis Through Its Role in Regulating Hepatic Inflammation and Lipid Metabolism

(2020) Hui-Chao Tao et al.   Frontiers in Immunology

Combination therapy for non-alcoholic steatohepatitis: rationale, opportunities and challenges

(2020) Jean-François Dufour et al.   GUT

Nonalcoholic Steatohepatitis

(2020) Adam C. Sheka et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

High-trans fatty acid and high-sugar diets can cause mice with non-alcoholic steatohepatitis with liver fibrosis and potential pathogenesis

(2020) Xin Xin et al.   Nutrition & Metabolism

The increased amount of coffee consumption lowers the incidence of fatty liver disease in Korean men

(2020) Hye-Kyung Chung et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Effects of a Low Dose of Caffeine Alone or as Part of a Green Coffee Extract, in a Rat Dietary Model of Lean Non-Alcoholic Fatty Liver Disease without Inflammation

(2020) Ana Magdalena Velázquez et al.   Nutrients

Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention

(2020) Daniel Q. Huang et al.   Nature Reviews Gastroenterology & Hepatology

Coadministration of epigallocatechin-3-gallate (EGCG) and caffeine in low dose ameliorates obesity and nonalcoholic fatty liver disease in obese rats

(2019) Zhe Yang et al.   PHYTOTHERAPY RESEARCH

Preventive Efficiency of Green Tea and Its Components on Non-alcoholic Fatty Liver Disease

(2019) Jie Zhou et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

From NASH to HCC: current concepts and future challenges

(2019) Quentin M. Anstee et al.   Nature Reviews Gastroenterology & Hepatology

Association between Lysosomal Dysfunction and Obesity-Related Pathology: A Key Knowledge to Prevent Metabolic Syndrome

(2019) Yuhei Mizunoe et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Raw Bowl Tea (Tuocha) Polyphenol Prevention of Nonalcoholic Fatty Liver Disease by Regulating Intestinal Function in Mice

(2019) Bihui Liu et al.   Biomolecules

Efficacy and Mechanism of Polymerized Anthocyanin from Grape-Skin Extract on High-Fat-Diet-Induced Nonalcoholic Fatty Liver Disease

(2019) Meiqi Fan et al.   Nutrients

Natural Active Compounds from Plant Food and Chinese Herbal Medicine for Nonalcoholic Fatty Liver Disease

(2018) Qian Liu et al.   CURRENT PHARMACEUTICAL DESIGN

Determinants of fibrosis progression and regression in NASH

(2018) Detlef Schuppan et al.   JOURNAL OF HEPATOLOGY

Caffeine affects HFD-induced hepatic steatosis by multifactorial intervention

(2017) MG Helal et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Caffeine, coffee, and appetite control: a review

(2017) Matthew M. Schubert et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Caffeine intake decreases oxidative stress and inflammatory biomarkers in experimental liver diseases induced by thioacetamide: Biochemical and histological study

(2017) Mona G Amer et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Potential Biological Effects of (-)-Epigallocatechin-3-gallate on the Treatment of Nonalcoholic Fatty Liver Disease

(2017) Cheng Chen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention

(2017) Zobair Younossi et al.   Nature Reviews Gastroenterology & Hepatology

miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice

(2017) Pedro M Rodrigues et al.   Cell Death & Disease

Recent advances in tea polysaccharides: Extraction, purification, physicochemical characterization and bioactivities

(2016) Guijie Chen et al.   CARBOHYDRATE POLYMERS

Coffee and tea consumption in relation with non-alcoholic fatty liver and metabolic syndrome: A systematic review and meta-analysis of observational studies

(2016) Stefano Marventano et al.   CLINICAL NUTRITION

CXCR4 dysfunction in non-alcoholic steatohepatitis in mice and patients

(2015) Hédia Boujedidi et al.   CLINICAL SCIENCE

Association between caffeine consumption and nonalcoholic fatty liver disease: a systemic review and meta-analysis

(2015) Huafeng Shen et al.   Therapeutic Advances in Gastroenterology

Non-alcoholic steatohepatitis and preneoplastic lesions develop in the liver of obese and hypertensive rats: Suppressing effects of EGCG on the development of liver lesions

(2013) Takahiro Kochi et al.   CANCER LETTERS

Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways

(2013) Jia Xiao et al.   EUROPEAN JOURNAL OF NUTRITION

Coffee and caffeine intake and incidence of type 2 diabetes mellitus: a meta-analysis of prospective studies

(2013) Xiubo Jiang et al.   EUROPEAN JOURNAL OF NUTRITION

Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice

(2013) Rohit A. Sinha et al.   HEPATOLOGY

Therapeutic potential of green tea in nonalcoholic fatty liver disease

(2012) Christopher Masterjohn et al.   NUTRITION REVIEWS

Coffee consumption and reduced risk of hepatocellular carcinoma: findings from the Singapore Chinese Health Study

(2011) Shane Johnson et al.   CANCER CAUSES & CONTROL

Association of coffee and caffeine consumption with fatty liver disease, nonalcoholic steatohepatitis, and degree of hepatic fibrosis

(2011) Jeffrey W. Molloy et al.   HEPATOLOGY

Protective Role of Coffee in Non-alcoholic Fatty Liver Disease (NAFLD)

(2010) Daniela Catalano et al.   DIGESTIVE DISEASES AND SCIENCES

Caffeine protects against alcoholic liver injury by attenuating inflammatory response and oxidative stress

(2010) Xiongwen Lv et al.   INFLAMMATION RESEARCH

Moderate coffee consumption reduces the risk of hepatocellular carcinoma in hepatitis B chronic carriers: a case-control study

(2010) W. W.-m. Leung et al.   JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH

Increased caffeine consumption is associated with reduced hepatic fibrosis

(2009) Apurva A. Modi et al.   HEPATOLOGY

Epigallocatechin gallate attenuates experimental non-alcoholic steatohepatitis induced by high fat diet

(2007) Nalan Kuzu et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY