Nrf2 plays a critical role in the metabolic response during and after spaceflight

Molecular basis for the disruption of Keap1–Nrf2 interaction via Hinge & Latch mechanism

(2021) Yuta Horie et al.   Communications Biology

Nuclear factor E2-related factor 2 (NRF2) deficiency accelerates fast fibre type transition in soleus muscle during space flight

(2021) Takuto Hayashi et al.   Communications Biology

Nrf2 Suppresses Oxidative Stress and Inflammation in App Knock-In Alzheimer’s Disease Model Mice

(2020) Akira Uruno et al.   MOLECULAR AND CELLULAR BIOLOGY

Ethacrynic acid targets GSTM1 to ameliorate obesity by promoting browning of white adipocytes

(2020) Zhaomeng Cui et al.   Protein & Cell

Randomized Clinical Trial on the Effect of Bardoxolone Methyl on GFR in Diabetic Kidney Disease Patients (TSUBAKI Study)

(2020) Masaomi Nangaku et al.   Kidney International Reports

Nrf2 contributes to the weight gain of mice during space travel

(2020) Takafumi Suzuki et al.   Communications Biology

Identification of biomarkers to diagnose diseases and find adverse drug reactions by metabolomics

(2020) Daisuke Saigusa et al.   Drug Metabolism and Pharmacokinetics

Multi-omic, Single-Cell, and Biochemical Profiles of Astronauts Guide Pharmacological Strategies for Returning to Gravity

(2020) Monica L. Gertz et al.   Cell Reports

Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap1

(2019) Takafumi Suzuki et al.   Cell Reports

Identification of novel biomarkers of hepatocellular carcinoma by a high definition mass spectrometry; UHPLC‐QTOF/MS and DESI‐MSI

(2019) Koshi Nagai et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Thrombospondin-1 Exacerbates Acute Liver Failure and Hepatic Encephalopathy Pathology in Mice by Activating Transforming Growth Factor β1

(2019) Brandi Jefferson et al.   AMERICAN JOURNAL OF PATHOLOGY

Dimethyl Fumarate: A Review in Relapsing-Remitting MS

(2019) Hannah A. Blair   DRUGS

Skeletal changes during and after spaceflight

(2018) Laurence Vico et al.   Nature Reviews Rheumatology

The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis

(2018) Masayuki Yamamoto et al.   PHYSIOLOGICAL REVIEWS

Recent Progress in Space Physiology and Aging

(2018) Felice Strollo et al.   Frontiers in Physiology

Comprehensive analysis of phospholipids in the brain, heart, kidney, and liver: brain phospholipids are least enriched with polyunsaturated fatty acids

(2017) Jaewoo Choi et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Nrf2 Improves Leptin and Insulin Resistance Provoked by Hypothalamic Oxidative Stress

(2017) Yoko Yagishita et al.   Cell Reports

Carboxylesterases in lipid metabolism: from mouse to human

(2017) Jihong Lian et al.   Protein & Cell

Erythropoietin (EPO) ameliorates obesity and glucose homeostasis by promoting thermogenesis and endocrine function of classical brown adipose tissue (BAT) in diet-induced obese mice

(2017) Kazuki Kodo et al.   PLoS One

Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism

(2016) Akira Uruno et al.   MOLECULAR AND CELLULAR BIOLOGY

Spaceflight Activates Lipotoxic Pathways in Mouse Liver

(2016) Karen R. Jonscher et al.   PLoS One

The Keap1–Nrf2 system and diabetes mellitus

(2015) Akira Uruno et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Adipose ABCG1: A potential therapeutic target in obesity?

(2015) Eric Frisdal et al.   Adipocyte

Adipocyte ATP-Binding Cassette G1 Promotes Triglyceride Storage, Fat Mass Growth, and Human Obesity

(2014) Eric Frisdal et al.   DIABETES

Direct activating effects of adrenocorticotropic hormone (ACTH) on brown adipose tissue are attenuated by corticosterone

(2014) Johanna C. van den Beukel et al.   FASEB JOURNAL

Nrf2 induces fibroblast growth factor 21 in diabetic mice

(2014) Yuki Furusawa et al.   GENES TO CELLS

A versatile ultra-high performance LC-MS method for lipid profiling

(2014) Oskar L. Knittelfelder et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease

(2013) James L. McManaman et al.   JOURNAL OF LIPID RESEARCH

The Keap1-Nrf2 System Prevents Onset of Diabetes Mellitus

(2013) A. Uruno et al.   MOLECULAR AND CELLULAR BIOLOGY

Role of Endogenous Cortistatin in the Regulation of Ghrelin System Expression at Pancreatic Level under Normal and Obese Conditions

(2013) Belén Chanclón et al.   PLoS One

Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

(2012) Yoichiro Mitsuishi et al.   CANCER CELL

Space physiology II: adaptation of the central nervous system to space flight—past, current, and future studies

(2012) Gilles Clément et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Weight, muscle and bone loss during space flight: another perspective

(2012) T. P. Stein   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Weight Loss in Humans in Space

(2011) Akiko Matsumoto et al.   AVIATION SPACE AND ENVIRONMENTAL MEDICINE

Long-Duration Space Flight and Bed Rest Effects on Testosterone and Other Steroids

(2011) Scott M. Smith et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Keap1–Nrf2 system as an in vivo sensor for electrophiles

(2011) Akira Uruno et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Disrupted erythropoietin signalling promotes obesity and alters hypothalamus proopiomelanocortin production

(2011) Ruifeng Teng et al.   Nature Communications

A Phospholipidomic Analysis of All Defined Human Plasma Lipoproteins

(2011) Monireh Dashti et al.   Scientific Reports

Enzymatic activities of the human AGPAT isoform 3 and isoform 5: localization of AGPAT5 to mitochondria

(2010) Sneha S. Prasad et al.   JOURNAL OF LIPID RESEARCH

Sfrp5 Is an Anti-Inflammatory Adipokine That Modulates Metabolic Dysfunction in Obesity

(2010) N. Ouchi et al.   SCIENCE

Stress-Activated Cap'n'collar Transcription Factors in Aging and Human Disease

(2010) G. P. Sykiotis et al.   Science Signaling