Erythropoietin (EPO) ameliorates obesity and glucose homeostasis by promoting thermogenesis and endocrine function of classical brown adipose tissue (BAT) in diet-induced obese mice

Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice

(2016) Qi Gong et al.   HEPATOLOGY

Erythropoietin does not activate erythropoietin receptor signaling or lipolytic pathways in human subcutaneous white adipose tissue in vivo

(2016) Britt Christensen et al.   Lipids in Health and Disease

Brown adipose tissue as a secretory organ

(2016) Francesc Villarroya et al.   Nature Reviews Endocrinology

Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis

(2015) Labros Sidossis et al.   JOURNAL OF CLINICAL INVESTIGATION

Chronic erythropoietin treatment improves diet-induced glucose intolerance in rats

(2015) C. Caillaud et al.   JOURNAL OF ENDOCRINOLOGY

Hepatic insulin resistance and increased hepatic glucose production in mice lackingFgf21

(2015) João Paulo G Camporez et al.   JOURNAL OF ENDOCRINOLOGY

Erythropoietin enhances whole body lipid oxidation during prolonged exercise in humans

(2015) Corinne Caillaud et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Erythropoietin alleviates hepatic insulin resistance via PPARγ-dependent AKT activation

(2015) Zhijuan Ge et al.   Scientific Reports

Nonerythropoietic Erythropoietin-Derived Peptide Suppresses Adipogenesis, Inflammation, Obesity and Insulin Resistance

(2015) Yuqi Liu et al.   Scientific Reports

Beyond Erythropoiesis: Emerging Metabolic Roles of Erythropoietin

(2014) M. Woo et al.   DIABETES

Erythropoietin Signaling: A Novel Regulator of White Adipose Tissue Inflammation During Diet-Induced Obesity

(2014) M. Alnaeeli et al.   DIABETES

Human brown adipose tissue: regulation and anti-obesity potential [Review]

(2014) Masayuki Saito   ENDOCRINE JOURNAL

AMPK is involved in mediation of erythropoietin influence on metabolic activity and reactive oxygen species production in white adipocytes

(2014) Li Wang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Effects of an 8-weeks erythropoietin treatment on mitochondrial and whole body fat oxidation capacity during exercise in healthy males

(2014) Amelia Guadalupe-Grau et al.   JOURNAL OF SPORTS SCIENCES

Miglitol increases energy expenditure by upregulating uncoupling protein 1 of brown adipose tissue and reduces obesity in dietary-induced obese mice

(2014) Satoru Sugimoto et al.   Nutrition & Metabolism

An endocrine role for brown adipose tissue?

(2013) Joan Villarroya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

MicroRNA-133 Controls Brown Adipose Determination in Skeletal Muscle Satellite Cells by Targeting Prdm16

(2013) Hang Yin et al.   Cell Metabolism

PPAR  and Sirt1 Mediate Erythropoietin Action in Increasing Metabolic Activity and Browning of White Adipocytes to Protect Against Obesity and Metabolic Disorders

(2013) L. Wang et al.   DIABETES

miR-133a Regulates Adipocyte Browning In Vivo

(2013) Weiyi Liu et al.   PLoS Genetics

Tyk2 and Stat3 Regulate Brown Adipose Tissue Differentiation and Obesity

(2012) Marta Derecka et al.   Cell Metabolism

Erythropoietin administration acutely stimulates resting energy expenditure in healthy young men

(2012) Britt Christensen et al.   JOURNAL OF APPLIED PHYSIOLOGY

MyomiRs-133a/b turn off the heat

(2012) Jan-Wilhelm Kornfeld et al.   NATURE CELL BIOLOGY

MyomiR-133 regulates brown fat differentiation through Prdm16

(2012) Mirko Trajkovski et al.   NATURE CELL BIOLOGY

A Novel EPO Receptor Agonist Improves Glucose Tolerance via Glucose Uptake in Skeletal Muscle in a Mouse Model of Diabetes

(2011) Michael S. Scully et al.   Experimental Diabetes Research

Peroxisome Proliferator-activated Receptor α (PPARα) Induces PPARγ Coactivator 1α (PGC-1α) Gene Expression and Contributes to Thermogenic Activation of Brown Fat

(2011) Elayne Hondares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

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(2011) Dionysios Chartoumpekis et al.   MOLECULAR MEDICINE

Disrupted erythropoietin signalling promotes obesity and alters hypothalamus proopiomelanocortin production

(2011) Ruifeng Teng et al.   Nature Communications

Fibroblast Growth Factor 21 Action in the Brain Increases Energy Expenditure and Insulin Sensitivity in Obese Rats

(2010) D. A. Sarruf et al.   DIABETES

Erythropoietin treatment leads to reduced blood glucose levels and body mass: insights from murine models

(2010) Odelia Katz et al.   JOURNAL OF ENDOCRINOLOGY

Fibroblast Growth Factor 21 Controls Glycemia via Regulation of Hepatic Glucose Flux and Insulin Sensitivity

(2009) Eric D. Berglund et al.   ENDOCRINOLOGY

Functional Brown Adipose Tissue in Healthy Adults

(2009) Kirsi A. Virtanen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Erythropoietin Over-Expression Protects against Diet-Induced Obesity in Mice through Increased Fat Oxidation in Muscles

(2009) Pernille Hojman et al.   PLoS One

Association between Erythropoietin Responsiveness and Body Composition in Dialysis Patients

(2008) Peter Kotanko et al.   BLOOD PURIFICATION

Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice

(2008) J. Xu et al.   DIABETES

PRDM16 controls a brown fat/skeletal muscle switch

(2008) Patrick Seale et al.   NATURE