Spaceflight Activates Lipotoxic Pathways in Mouse Liver

Excessive bile acid activated NF-kappa B and promoted the development of alcoholic steatohepatitis in farnesoid X receptor deficient mice

(2015) Wei-Bin Wu et al.   BIOCHIMIE

The link between Hepatic Vitamin A Metabolism and Nonalcoholic Fatty Liver Disease

(2015) Guoxun Chen   CURRENT DRUG TARGETS

Farnesoid X receptor: a master regulator of hepatic triglyceride and glucose homeostasis

(2014) Yang Jiao et al.   ACTA PHARMACOLOGICA SINICA

Regulation of peroxisomal lipid metabolism: The role of acyl-CoA and coenzyme A metabolizing enzymes

(2014) Mary C. Hunt et al.   BIOCHIMIE

Role of farnesoid X receptor in inflammation and resolution

(2014) Firdose Begum Shaik et al.   INFLAMMATION RESEARCH

Formation of Fenestrae in Murine Liver Sinusoids Depends on Plasmalemma Vesicle-Associated Protein and Is Required for Lipoprotein Passage

(2014) Leonie Herrnberger et al.   PLoS One

Extrahepatic complications of nonalcoholic fatty liver disease

(2013) Matthew J. Armstrong et al.   HEPATOLOGY

Peroxisome Proliferator-Activated Receptor-γ Activators Monascin and Rosiglitazone Attenuate Carboxymethyllysine-Induced Fibrosis in Hepatic Stellate Cells through Regulating the Oxidative Stress Pathway but Independent of the Receptor for Advanced Glycation End Products Signaling

(2013) Wei-Hsuan Hsu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The past, present, and future of National Aeronautics and Space Administration spaceflight diet in support of microgravity rodent experiments

(2013) Gwo-Shing Sun et al.   NUTRITION

Amplified Inhibition of Stellate Cell Activation Pathways by PPAR-γ, RAR and RXR Agonists

(2013) Efrat Sharvit et al.   PLoS One

The emerging role of acyl-CoA thioesterases and acyltransferases in regulating peroxisomal lipid metabolism

(2012) Mary C. Hunt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Activation of the Farnesoid X Receptor Induces Hepatic Expression and Secretion of Fibroblast Growth Factor 21

(2012) Holly A. Cyphert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin resistance: An adaptive mechanism becomes maladaptive in the current environment — An evolutionary perspective

(2012) Agathocles Tsatsoulis et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Biomarkers of Inflammation, Immunosuppression and Stress Are Revealed by Metabolomic Profiling of Tuberculosis Patients

(2012) January Weiner et al.   PLoS One

New players on the metabolic stage

(2012) David E. Cohen   Adipocyte

Valproic acid utilizes the isoleucine breakdown pathway for its complete β-oxidation

(2011) Paula B.M. Luís et al.   BIOCHEMICAL PHARMACOLOGY

Analysis, occurrence, and function of 9-cis-retinoic acid

(2011) Maureen A. Kane   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lipid metabolism in mammalian tissues and its control by retinoic acid

(2011) M. Luisa Bonet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Effect of the regulation of retinoid X receptor-α gene expression on rat hepatic fibrosis

(2011) Zheng Wang et al.   HEPATOLOGY RESEARCH

Assessment of liver steatosis and fibrosis in rats using integrated coherent anti-Stokes Raman scattering and multiphoton imaging technique

(2011) Jian Lin et al.   JOURNAL OF BIOMEDICAL OPTICS

PAI-1 in tissue fibrosis

(2011) Asish K. Ghosh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Insulin resistance and liver microcirculation in a rat model of early NAFLD

(2011) Marcos Pasarín et al.   JOURNAL OF HEPATOLOGY

Distinct Populations of Hepatic Stellate Cells in the Mouse Liver Have Different Capacities for Retinoid and Lipid Storage

(2011) Diana N. D'Ambrosio et al.   PLoS One

Hepatic stellate cell (vitamin A-storing cell) and its relative – past, present and future

(2010) Haruki Senoo et al.   CELL BIOLOGY INTERNATIONAL

Disuse of the musculo-skeletal system in space and on earth

(2010) M. V. Narici et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Rodent Models for Metabolic Syndrome Research

(2010) Sunil K. Panchal et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Animal models of nonalcoholic fatty liver disease

(2010) Lionel Hebbard et al.   Nature Reviews Gastroenterology & Hepatology

Evolving challenges in hepatic fibrosis

(2010) Scott L. Friedman   Nature Reviews Gastroenterology & Hepatology

Evaluation of the nutrient-upgraded rodent food bar for rodent spaceflight experiments

(2010) Gwo-Shing Sun et al.   NUTRITION

Peroxisome Proliferator-Activated Receptor Alpha Target Genes

(2010) Maryam Rakhshandehroo et al.   PPAR Research

Organization of GC/MS and LC/MS metabolomics data into chemical libraries

(2010) Corey D DeHaven et al.   Journal of Cheminformatics

Integrated, Nontargeted Ultrahigh Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry Platform for the Identification and Relative Quantification of the Small-Molecule Complement of Biological Systems

(2009) Anne M. Evans et al.   ANALYTICAL CHEMISTRY

EGAN: exploratory gene association networks

(2009) Jesse Paquette et al.   BIOINFORMATICS

Effects of spaceflight on innate immune function and antioxidant gene expression

(2009) Farnaz P. Baqai et al.   JOURNAL OF APPLIED PHYSIOLOGY

Spaceflight modulates expression of extracellular matrix, adhesion, and profibrotic molecules in mouse lung

(2009) Jian Tian et al.   JOURNAL OF APPLIED PHYSIOLOGY

n-3 PUFA as Regulators of Cardiac Gene Transcription: A New Link between PPAR Activation and Fatty Acid Composition

(2009) Mattia Di Nunzio et al.   LIPIDS

Activation of Retinoic Acid Receptors by Dihydroretinoids

(2009) A. R. Moise et al.   MOLECULAR PHARMACOLOGY

Coherent Anti-Stokes Raman Scattering Microscopy: Chemical Imaging for Biology and Medicine

(2008) Conor L. Evans et al.   Annual Review of Analytical Chemistry

Hepatic stellate cell lipid droplets: A specialized lipid droplet for retinoid storage

(2008) William S. Blaner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Differential pattern of lipid droplet-associated proteins andde novoperilipin expression in hepatocyte steatogenesis

(2008) Beate Katharina Straub et al.   HEPATOLOGY

Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

(2008) Scott L. Friedman   PHYSIOLOGICAL REVIEWS