Comprehensive Statistical and Bioinformatics Analysis in the Deciphering of Putative Mechanisms by Which Lipid-Associated GWAS Loci Contribute to Coronary Artery Disease

The Link between Type 2 Diabetes Mellitus and the Polymorphisms of Glutathione-Metabolizing Genes Suggests a New Hypothesis Explaining Disease Initiation and Progression

(2021) Iuliia Azarova et al.   Life-Basel

Pharmacogenetic loci for rosuvastatin are associated with intima-media thickness change and coronary artery disease risk

(2021) Stanislav Kononov et al.   PHARMACOGENOMICS

rs11927381 Polymorphism and Type 2 Diabetes Mellitus: Contribution of Smoking to the Realization of Susceptibility to the Disease

(2020) I. E. Azarova et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Association of small dense low-density lipoprotein with cardiovascular outcome in patients with coronary artery disease and diabetes: a prospective, observational cohort study

(2020) Jing-Lu Jin et al.   Cardiovascular Diabetology

Interethnic differences in the prevalence of main cardiovascular pharmacogenetic biomarkers

(2020) Karin Mirzaev et al.   PHARMACOGENOMICS

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

(2019) Paul S de Vries et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Genetic analyses of diverse populations improves discovery for complex traits

(2019) Genevieve L. Wojcik et al.   NATURE

A Novel Polymorphism in the Promoter of the CYP4A11 Gene Is Associated with Susceptibility to Coronary Artery Disease

(2018) Svetlana Sirotina et al.   DISEASE MARKERS

A large electronic-health-record-based genome-wide study of serum lipids

(2018) Thomas J. Hoffmann et al.   NATURE GENETICS

Genome-wide association study identifies novel recessive genetic variants for high TGs in an Arab population

(2018) Prashantha Hebbar et al.   JOURNAL OF LIPID RESEARCH

atSNP Search: a web resource for statistically evaluating influence of human genetic variation on transcription factor binding

(2018) Sunyoung Shin et al.   BIOINFORMATICS

The Structure of Human Apolipoprotein C-1 in Four Different Crystal Forms

(2018) Alexander McPherson et al.   JOURNAL OF LIPID RESEARCH

Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program

(2018) Derek Klarin et al.   NATURE GENETICS

Polymorphisms of CYP2C8 , CYP2C9 and CYP2C19 and risk of coronary heart disease in Russian population

(2017) Alexey Polonikov et al.   GENE

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels

(2017) Cassandra N. Spracklen et al.   HUMAN MOLECULAR GENETICS

A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms

(2017) Salome Mack et al.   JOURNAL OF LIPID RESEARCH

Genetic determinants of inherited susceptibility to hypercholesterolemia – a comprehensive literature review

(2017) CS Paththinige et al.   Lipids in Health and Disease

Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

(2017) Wei Zhao et al.   NATURE GENETICS

Genetics of coronary artery disease: discovery, biology and clinical translation

(2017) Amit V. Khera et al.   NATURE REVIEWS GENETICS

Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex

(2017) Seung-Hyeon Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Aryl Hydrocarbon Receptor-Mediated Gene Activation

(2017) Kathrin Wiebke Schulte et al.   STRUCTURE

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

(2017) Peter K. Joshi et al.   Nature Communications

Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease

(2017) Pim van der Harst et al.   CIRCULATION RESEARCH

Early markers of cardiovascular disease are associated with occupational exposure to polycyclic aromatic hydrocarbons

(2017) Ayman Alhamdow et al.   Scientific Reports

Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation

(2016) Symen Ligthart et al.   BMC GENOMICS

Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences

(2016) Claudia Manzoni et al.   BRIEFINGS IN BIOINFORMATICS

SCARB1 Gene Variants Are Associated With the Phenotype of Combined High High-Density Lipoprotein Cholesterol and High Lipoprotein (a)CLINICAL PERSPECTIVE

(2016) Xiaoping Yang et al.   Circulation-Cardiovascular Genetics

The association of urinary polycyclic aromatic hydrocarbon biomarkers and cardiovascular disease in the US population

(2016) Omayma Alshaarawy et al.   ENVIRONMENT INTERNATIONAL

Genome-Wide Analysis of DNA Methylation and Cigarette Smoking in a Chinese Population

(2016) Xiaoyan Zhu et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Preferential epigenetic programming of estrogen response after in utero xenoestrogen (bisphenol-A) exposure

(2016) Elisa M. Jorgensen et al.   FASEB JOURNAL

Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis

(2016) David A. Hinds et al.   HUMAN MOLECULAR GENETICS

Increased carotid intima-media thickness and coronary artery disease share more links besides inflammation

(2016) Kosmas I. Paraskevas   INTERNATIONAL JOURNAL OF CARDIOLOGY

Carotid Intima-Media Thickness for Atherosclerosis

(2016) Tomohisa Nezu et al.   Journal of Atherosclerosis and Thrombosis

SCARB1 Gene Variants Are Associated With the Phenotype of Combined High High-Density Lipoprotein Cholesterol and High Lipoprotein (a)CLINICAL PERSPECTIVE

(2016) Xiaoping Yang et al.   Circulation-Cardiovascular Genetics

Meta-analysis of 65,734 Individuals Identifies TSPAN15 and SLC44A2 as Two Susceptibility Loci for Venous Thromboembolism

(2015) Marine Germain et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-wide association study on progression of carotid artery intima media thickness over 10 years in a Chinese cohort

(2015) Gaoqiang Xie et al.   ATHEROSCLEROSIS

Altered erythrocyte membrane protein composition mirrors pleiotropic effects of hypertension susceptibility genes and disease pathogenesis

(2015) Alexey V. Polonikov et al.   JOURNAL OF HYPERTENSION

New genetic loci link adipose and insulin biology to body fat distribution

(2015) Dmitry Shungin et al.   NATURE

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

(2015) S. Liu et al.   SCIENCE

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

(2015) Thomas W. Winkler et al.   PLoS Genetics

Uninephrectomy augments the effects of high fat diet induced obesity on gene expression in mouse kidney

(2014) Zhibo Gai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age

(2014) Joris Deelen et al.   HUMAN MOLECULAR GENETICS

Gene Expression Signatures of Coronary Heart Disease

(2013) Roby Joehanes et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Increased carotid intima-media thickness associated with high hs-CRP levels is a predictor of unstable coronary artery disease : cardiovascular topic

(2013) Sejran Ahmet Abdushi et al.   Cardiovascular Journal of Africa

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Seven new loci associated with age-related macular degeneration

(2013) Lars G Fritsche et al.   NATURE GENETICS

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

Structurally distinct polycyclic aromatic hydrocarbons induce differential transcriptional responses in developing zebrafish

(2013) Britton C. Goodale et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Association ofPPP1R3Bpolymorphisms with blood lipid and C-reactive protein levels in a Chinese population (中国汉族人群中PPP1R3B基因多态性与血脂及C 反应蛋白水平的相关性)

(2013) Yongxian Zhang et al.   Journal of Diabetes

Association of Genetic Variants Influencing Lipid Levels with Coronary Artery Disease in Japanese Individuals

(2012) Fumihiko Takeuchi et al.   PLoS One

Heart Disease and Stroke Statistics—2012 Update

(2011) et al.   CIRCULATION

Ets2 Determines the Inflammatory State of Endothelial Cells in Advanced Atherosclerotic Lesions

(2011) Caroline Cheng et al.   CIRCULATION RESEARCH

Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

(2011) R. M. Gadaleta et al.   GUT

Structure and Binding Mechanism of Vascular Endothelial Cadherin: A Divergent Classical Cadherin

(2011) Julia Brasch et al.   JOURNAL OF MOLECULAR BIOLOGY

The Hemostatic System as a Modulator of Atherosclerosis

(2011) Julian Ilcheff Borissoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease

(2010) Dawn M. Waterworth et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

mbmdr: an R package for exploring gene–gene interactions associated with binary or quantitative traits

(2010) M. Luz Calle et al.   BIOINFORMATICS

Overexpression of STARD3 in human monocyte/macrophages induces an anti-atherogenic lipid phenotype

(2010) Faye Borthwick et al.   CLINICAL SCIENCE

Lipoprotein(a) as a cardiovascular risk factor: current status

(2010) Børge G. Nordestgaard et al.   EUROPEAN HEART JOURNAL

Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Association Study of Lp-PLA2 Activity and Mass in the Framingham Heart Study

(2010) Sunil Suchindran et al.   PLoS Genetics

Is thrombin a key player in the 'coagulation-atherogenesis' maze?

(2009) J. I. Borissoff et al.   CARDIOVASCULAR RESEARCH

Architectural roles of multiple chromatin insulators at the human apolipoprotein gene cluster

(2009) Tsuyoshi Mishiro et al.   EMBO JOURNAL

GPS2 Is Required for Cholesterol Efflux by Triggering Histone Demethylation, LXR Recruitment, and Coregulator Assembly at the ABCG1 Locus

(2009) Tomas Jakobsson et al.   MOLECULAR CELL

Genome-Wide Association Studies in an Isolated Founder Population from the Pacific Island of Kosrae

(2009) Jennifer K. Lowe et al.   PLoS Genetics

Genetic Loci Associated With Plasma Concentration of Low-Density Lipoprotein Cholesterol, High-Density Lipoprotein Cholesterol, Triglycerides, Apolipoprotein A1, and Apolipoprotein B Among 6382 White Women in Genome-Wide Analysis With Replication

(2008) Daniel I. Chasman et al.   Circulation-Cardiovascular Genetics

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

(2008) Cristen J Willer et al.   NATURE GENETICS

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

(2008) Sekar Kathiresan et al.   NATURE GENETICS

Improving strategies for detecting genetic patterns of disease susceptibility in association studies

(2008) M. L. Calle et al.   STATISTICS IN MEDICINE

Candidate Single-Nucleotide Polymorphisms From a Genomewide Association Study of Alzheimer Disease

(2007) Hao Li et al.   ARCHIVES OF NEUROLOGY