Genetic analyses of diverse populations improves discovery for complex traits

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

(2018) James J. Lee et al.   NATURE GENETICS

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

(2018) Amit V. Khera et al.   NATURE GENETICS

Association of Sickle Cell Trait With Hemoglobin A1c in African Americans

(2017) Mary E. Lacy et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Model-free Estimation of Recent Genetic Relatedness

(2016) Matthew P. Conomos et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic Diversity and Association Studies in US Hispanic/Latino Populations: Applications in the Hispanic Community Health Study/Study of Latinos

(2016) Matthew P. Conomos et al.   AMERICAN JOURNAL OF HUMAN GENETICS

FINEMAP: efficient variable selection using summary data from genome-wide association studies

(2016) Christian Benner et al.   BIOINFORMATICS

The (in)famous GWAS P-value threshold revisited and updated for low-frequency variants

(2016) João Fadista et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Prostate Cancer Susceptibility in Men of African Ancestry at 8q24

(2016) Ying Han et al.   JNCI-Journal of the National Cancer Institute

Genomics is failing on diversity

(2016) Alice B. Popejoy et al.   NATURE

The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)

(2016) Jacqueline MacArthur et al.   NUCLEIC ACIDS RESEARCH

Pharmacogenomic implications of the evolutionary history of infectious diseases in Africa

(2016) J L Baker et al.   PHARMACOGENOMICS JOURNAL

Prostate Cancer Susceptibility in Men of African Ancestry at 8q24

(2016) Ying Han et al.   JNCI-Journal of the National Cancer Institute

Strategies for Enriching Variant Coverage in Candidate Disease Loci on a Multiethnic Genotyping Array

(2016) Stephanie A. Bien et al.   PLoS One

Robust Inference of Population Structure for Ancestry Prediction and Correction of Stratification in the Presence of Relatedness

(2015) Matthew P. Conomos et al.   GENETIC EPIDEMIOLOGY

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

A New Initiative on Precision Medicine

(2015) Francis S. Collins et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Multivariate Genome-Wide Association Analysis of 10 LDL Subfractions, and Their Response to Statin Treatment, in 1868 Caucasians

(2015) Heejung Shim et al.   PLoS One

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Genetic Association Analysis under Complex Survey Sampling: The Hispanic Community Health Study/Study of Latinos

(2014) Dan-Yu Lin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Association of a Low-Frequency Variant inHNF1AWith Type 2 Diabetes in a Latino Population

(2014) Karol Estrada et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

(2014) Ida Moltke et al.   NATURE

Defining the role of common variation in the genomic and biological architecture of adult human height

(2014) Andrew R Wood et al.   NATURE GENETICS

Generalization and Dilution of Association Results from European GWAS in Populations of Non-European Ancestry: The PAGE Study

(2013) Christopher S. Carlson et al.   PLOS BIOLOGY

A high-performance computing toolset for relatedness and principal component analysis of SNP data

(2012) X. Zheng et al.   BIOINFORMATICS

Effects of hemoglobin C, D, E, and S traits on measurements of HbA1c by six methods

(2012) Chia-Ni Lin et al.   CLINICA CHIMICA ACTA

A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer

(2012) Julius Gudmundsson et al.   NATURE GENETICS

Melanesian Blond Hair Is Caused by an Amino Acid Change in TYRP1

(2012) E. E. Kenny et al.   SCIENCE

Genomics for the world

(2011) Carlos D. Bustamante et al.   NATURE

A linear complexity phasing method for thousands of genomes

(2011) Olivier Delaneau et al.   NATURE METHODS

Hunter-gatherer genomic diversity suggests a southern African origin for modern humans

(2011) B. M. Henn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Demographic history and rare allele sharing among human populations

(2011) S. Gravel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

On the relative efficiency of using summary statistics versus individual-level data in meta-analysis

(2010) D. Y. Lin et al.   BIOMETRIKA

Next generation disparities in human genomics: concerns and remedies

(2009) Anna C. Need et al.   TRENDS IN GENETICS

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Effects of Hemoglobin C and S Traits on the Results of 14 Commercial Glycated Hemoglobin Assays

(2008) Shella K. Mongia et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY