KDM6A Regulates Cell Plasticity and Pancreatic Cancer Progression by Noncanonical Activin Pathway
Published 2021 View Full Article
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Title
KDM6A Regulates Cell Plasticity and Pancreatic Cancer Progression by Noncanonical Activin Pathway
Authors
Keywords
Epigenetics, Cancer Cell Plasticity, Metastasis, Activin A
Journal
Cellular and Molecular Gastroenterology and Hepatology
Volume 13, Issue 2, Pages 643-667
Publisher
Elsevier BV
Online
2021-09-27
DOI
10.1016/j.jcmgh.2021.09.014
References
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Note: Only part of the references are listed.- Loss of activating transcription factor 3 prevents KRAS-mediated pancreatic cancer
- (2021) Nawab Azizi et al. ONCOGENE
- Oncogene-induced senescence limits the progression of pancreatic neoplasia through production of Activin A
- (2020) Yajie Zhao et al. CANCER RESEARCH
- Pancreatic cancer
- (2020) Jonathan D Mizrahi et al. LANCET
- The Histone Demethylase UTX/KDM6A in Cancer: Progress and Puzzles
- (2019) Wolfgang A. Schulz et al. INTERNATIONAL JOURNAL OF CANCER
- Loss of KDM6A confers drug resistance in acute myeloid leukemia
- (2019) Sophie M. Stief et al. LEUKEMIA
- Expression and prognostic value of NSD1 and SETD2 in pancreatic ductal adenocarcinoma and its precursor lesions
- (2019) Mark Ettel et al. PATHOLOGY
- Elevated Circulating Activin A Levels in Patients With Malignant Pleural Mesothelioma Are Related to Cancer Cachexia and Reduced Response to Platinum-based Chemotherapy
- (2019) Juuso Paajanen et al. Clinical Lung Cancer
- GATA3 recruits UTX for gene transcriptional activation to suppress metastasis of breast cancer
- (2019) Wenqian Yu et al. Cell Death & Disease
- Interleukin 22 Signaling Regulates Acinar Cell Plasticity to Promote Pancreatic Tumor Development in Mice
- (2019) Mirna Perusina Lanfranca et al. GASTROENTEROLOGY
- Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors
- (2018) Jaclyn Andricovich et al. CANCER CELL
- Loss of KDM6A characterizes a poor prognostic subtype of human pancreatic cancer and potentiates HDAC inhibitor lethality
- (2018) Shuichi Watanabe et al. INTERNATIONAL JOURNAL OF CANCER
- Untangling the genetics from the epigenetics in pancreatic cancer metastasis
- (2017) Christopher R Vakoc et al. NATURE GENETICS
- Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer
- (2017) Alvin P Makohon-Moore et al. NATURE GENETICS
- Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2
- (2017) Lian Dee Ler et al. Science Translational Medicine
- The H3K27me3-demethylase KDM6A is suppressed in breast cancer stem-like cells, and enables the resolution of bivalency during the mesenchymal-epithelial transition
- (2017) Joseph H. Taube et al. Oncotarget
- KDM6A addiction of cervical carcinoma cell lines is triggered by E7 and mediated by p21CIP1 suppression of replication stress
- (2017) David R. Soto et al. PLoS Pathogens
- Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS
- (2016) Wanglong Qiu et al. GASTROENTEROLOGY
- Tumor infiltrating lymphocytes and survival in patients with head and neck squamous cell carcinoma
- (2016) Nghia Nguyen et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- Genomic analyses identify molecular subtypes of pancreatic cancer
- (2016) Peter Bailey et al. NATURE
- Activins and Inhibins: Roles in Development, Physiology, and Disease
- (2016) Maria Namwanje et al. Cold Spring Harbor Perspectives in Biology
- Activin A induces skeletal muscle catabolism via p38β mitogen-activated protein kinase
- (2016) Hui Ding et al. Journal of Cachexia Sarcopenia and Muscle
- Activin signal promotes cancer progression and is involved in cachexia in a subset of pancreatic cancer
- (2015) Yosuke Togashi et al. CANCER LETTERS
- Whole genomes redefine the mutational landscape of pancreatic cancer
- (2015) Nicola Waddell et al. NATURE
- Intertwining of Activin A and TGFβ Signaling: Dual Roles in Cancer Progression and Cancer Cell Invasion
- (2014) Holli Loomans et al. Cancers
- The Epidemiology of Pancreatitis and Pancreatic Cancer
- (2013) Dhiraj Yadav et al. GASTROENTEROLOGY
- Use of Bru-Seq and BruChase-Seq for genome-wide assessment of the synthesis and stability of RNA
- (2013) Michelle T. Paulsen et al. METHODS
- Coordinated regulation of synthesis and stability of RNA during the acute TNF-induced proinflammatory response
- (2013) M. T. Paulsen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Roles of activin family in pancreatic development and homeostasis
- (2012) Ezra Wiater et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- TGFβ signalling in context
- (2012) Joan Massagué NATURE REVIEWS MOLECULAR CELL BIOLOGY
- UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity
- (2012) C. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Distant metastasis occurs late during the genetic evolution of pancreatic cancer
- (2010) Shinichi Yachida et al. NATURE
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