Do changes in microglial status underlie neurogenesis impairments and depressive-like behaviours induced by psychological stress? A systematic review in animal models

Unobtrusive monitoring of behavior and movement patterns to detect clinical depression severity level via smartphone

(2020) Mohammed T. Masud et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome

(2020) Irune Diaz-Aparicio et al.   JOURNAL OF NEUROSCIENCE

Do antidepressants promote neurogenesis in adult hippocampus? A systematic review and meta-analysis on naïve rodents

(2020) Cilene Lino de Oliveira et al.   PHARMACOLOGY & THERAPEUTICS

Depressive symptoms are associated with social isolation in face-to-face interaction networks

(2020) Timon Elmer et al.   Scientific Reports

Glucocorticoids prime the inflammatory response of human hippocampal cells through up-regulation of inflammatory pathways

(2020) Mark A. Horowitz et al.   BRAIN BEHAVIOR AND IMMUNITY

Melatonin Reverses the Depression-associated Behaviour and Regulates Microglia, Fractalkine Expression and Neurogenesis in Adult Mice Exposed to Chronic Mild Stress

(2020) Nelly Maritza Vega-Rivera et al.   NEUROSCIENCE

Ginsenoside Rg1 ameliorates chronic social defeat stress-induced depressive-like behaviors and hippocampal neuroinflammation

(2020) Ning Jiang et al.   LIFE SCIENCES

Depressive symptoms and risk of liver-related mortality in individuals with hepatitis B virus infection: a cohort study

(2020) In Young Cho et al.   Scientific Reports

Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors

(2019) Yang Yang et al.   Cell Death & Disease

Emotion Regulation of Hippocampus Using Real-Time fMRI Neurofeedback in Healthy Human

(2019) Yashuo Zhu et al.   Frontiers in Human Neuroscience

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation

(2019) Nathan Kelley et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antidepressant-Like Activity of Myelophil via Attenuation of Microglial-Mediated Neuroinflammation in Mice Undergoing Unpredictable Chronic Mild Stress

(2019) Jin-Seok Lee et al.   Frontiers in Pharmacology

Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation

(2019) Nadine Provençal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Minocycline inhibits microglial activation and alleviates depressive-like behaviors in male adolescent mice subjected to maternal separation

(2019) Yue Han et al.   PSYCHONEUROENDOCRINOLOGY

Glucocorticoid-Driven NLRP3 Inflammasome Activation in Hippocampal Microglia Mediates Chronic Stress-Induced Depressive-Like Behaviors

(2019) Xiujing Feng et al.   Frontiers in Molecular Neuroscience

FGF-2 signaling activation in the hippocampus contributes to the behavioral and cellular responses to puerarin

(2019) Jie Cheng et al.   BIOCHEMICAL PHARMACOLOGY

Icariin and icaritin ameliorated hippocampus neuroinflammation via mediating HMGB1 expression in social defeat model in mice

(2019) Lumei Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Microglial Morphometric Parameters Correlate With the Expression Level of IL-1β, and Allow Identifying Different Activated Morphotypes

(2019) María del Mar Fernández-Arjona et al.   Frontiers in Cellular Neuroscience

Associations between subclinical depressive symptoms and reduced brain volume in middle-aged to older adults

(2018) Sarah M. Szymkowicz et al.   AGING & MENTAL HEALTH

Association between virus exposure and depression in US adults

(2018) Shawn D. Gale et al.   PSYCHIATRY RESEARCH

A P2X7 receptor antagonist reverses behavioural alterations, microglial activation and neuroendocrine dysregulation in an unpredictable chronic mild stress (UCMS) model of depression in mice

(2018) Rai Khalid Farooq et al.   PSYCHONEUROENDOCRINOLOGY

Decoding microglia responses to psychosocial stress reveals blood-brain barrier breakdown that may drive stress susceptibility

(2018) Michael L. Lehmann et al.   Scientific Reports

Switching of the Microglial Activation Phenotype Is a Possible Treatment for Depression Disorder

(2018) Lijuan Zhang et al.   Frontiers in Cellular Neuroscience

FCPR16, a novel phosphodiesterase 4 inhibitor, produces an antidepressant-like effect in mice exposed to chronic unpredictable mild stress

(2018) Qiuping Zhong et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Inhibiting the microglia activation improves the spatial memory and adult neurogenesis in rat hippocampus during 48 h of sleep deprivation

(2017) Meetu Wadhwa et al.   Journal of Neuroinflammation

Microglia Morphological Categorization in a Rat Model of Neuroinflammation by Hierarchical Cluster and Principal Components Analysis

(2017) María del Mar Fernández-Arjona et al.   Frontiers in Cellular Neuroscience

Lifestyle Shapes the Dialogue between Environment, Microglia, and Adult Neurogenesis

(2016) Jorge Valero et al.   ACS Chemical Neuroscience

Forced swimming sabotages the morphological and synaptic maturation of newborn granule neurons and triggers a unique pro-inflammatory milieu in the hippocampus

(2016) María Llorens-Martín et al.   BRAIN BEHAVIOR AND IMMUNITY

Chronic peripheral inflammation, hippocampal neurogenesis, and behavior

(2016) Vera Chesnokova et al.   BRAIN BEHAVIOR AND IMMUNITY

Adult Neurogenesis in the Hippocampus: From Stem Cells to Behavior

(2016) J. Tiago Gonçalves et al.   CELL

Adverse early life environment increases hippocampal microglia abundance in conjunction with decreased neural stem cells in juvenile mice

(2016) Susan Cohen et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Low-dose lipopolysaccharide (LPS) inhibits aggressive and augments depressive behaviours in a chronic mild stress model in mice

(2016) Yvonne Couch et al.   Journal of Neuroinflammation

Neuroinflammatory Dynamics Underlie Memory Impairments after Repeated Social Defeat

(2016) Daniel B. McKim et al.   JOURNAL OF NEUROSCIENCE

Stress and corticosteroids regulate rat hippocampal mitochondrial DNA gene expression via the glucocorticoid receptor

(2016) Richard G. Hunter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stress and neuroinflammation: a systematic review of the effects of stress on microglia and the implications for mental illness

(2016) Marilia A. Calcia et al.   PSYCHOPHARMACOLOGY

Neuroinflammation Regulates Cognitive Impairment in Socially Defeated Mice

(2016) Madeline L. Pfau et al.   TRENDS IN NEUROSCIENCES

Hippocampal Neurogenesis, Neurotrophic Factors and Depression: Possible Therapeutic Targets?

(2015) Gianluca Serafini et al.   CNS & Neurological Disorders-Drug Targets

Stress Induces the Danger-Associated Molecular Pattern HMGB-1 in the Hippocampus of Male Sprague Dawley Rats: A Priming Stimulus of Microglia and the NLRP3 Inflammasome

(2015) M. D. Weber et al.   JOURNAL OF NEUROSCIENCE

Why is depression more prevalent in women?

(2015) Paul Albert   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Anti-depressant effects of phosphodiesterase 3 inhibitor cilostazol in chronic mild stress-treated mice after ischemic stroke

(2015) Yu Ri Kim et al.   PSYCHOPHARMACOLOGY

Depression as a Microglial Disease

(2015) Raz Yirmiya et al.   TRENDS IN NEUROSCIENCES

Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system

(2015) Antonis Koussounadis et al.   Scientific Reports

Microglia Development and Function

(2014) Debasis Nayak et al.   Annual Review of Immunology

Hippocampus remodeling by chronic stress accompanied by GR, proteasome and caspase-3 overexpression

(2014) M.A. Orlovsky et al.   BRAIN RESEARCH

Iptakalim confers an antidepressant effect in a chronic mild stress model of depression through regulating neuro-inflammation and neurogenesis

(2014) Ming Lu et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Maternal sleep deprivation inhibits hippocampal neurogenesis associated with inflammatory response in young offspring rats

(2014) Qiuying Zhao et al.   NEUROBIOLOGY OF DISEASE

Stimulation of Systemic Low-Grade Inflammation by Psychosocial Stress

(2014) Nicolas Rohleder   PSYCHOSOMATIC MEDICINE

Dynamic microglial alterations underlie stress-induced depressive-like behavior and suppressed neurogenesis

(2013) T Kreisel et al.   MOLECULAR PSYCHIATRY

Glucocorticoid-Related Molecular Signaling Pathways Regulating Hippocampal Neurogenesis

(2013) Christoph Anacker et al.   NEUROPSYCHOPHARMACOLOGY

Inflammatory cytokines in depression: Neurobiological mechanisms and therapeutic implications

(2013) J.C. Felger et al.   NEUROSCIENCE

Role for the kinase SGK1 in stress, depression, and glucocorticoid effects on hippocampal neurogenesis

(2013) C. Anacker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The absence of P2X7 receptors (P2rx7) on non-haematopoietic cells leads to selective alteration in mood-related behaviour with dysregulated gene expression and stress reactivity in mice

(2012) Cecilia Csölle et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Review: Activation patterns of microglia and their identification in the human brain

(2012) D. Boche et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Negative regulation of inflammation by SIRT1

(2012) Jun Xie et al.   PHARMACOLOGICAL RESEARCH

Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk

(2012) S. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurobiological studies of fatigue

(2012) Mary E. Harrington   PROGRESS IN NEUROBIOLOGY

Microglial Activation – Tuning and Pruning Adult Neurogenesis

(2012) Christine T. Ekdahl   Frontiers in Pharmacology

Stress, stress hormones, and adult neurogenesis

(2011) Timothy J. Schoenfeld et al.   EXPERIMENTAL NEUROLOGY

Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice

(2011) Carlo Perego et al.   Journal of Neuroinflammation

Antidepressants increase human hippocampal neurogenesis by activating the glucocorticoid receptor

(2011) C Anacker et al.   MOLECULAR PSYCHIATRY

Can adult neurogenesis buffer stress responses and depressive behaviour?

(2011) C Anacker et al.   MOLECULAR PSYCHIATRY

Adult hippocampal neurogenesis buffers stress responses and depressive behaviour

(2011) Jason S. Snyder et al.   NATURE

Comparison of Glucocorticoid Receptor and Ionized Calcium-Binding Adapter Molecule 1 Immunoreactivity in the Adult and Aged Gerbil Hippocampus Following Repeated Restraint Stress

(2011) Joon Ha Park et al.   NEUROCHEMICAL RESEARCH

Stress and emotional memory: a matter of timing

(2011) Marian Joëls et al.   TRENDS IN COGNITIVE SCIENCES

Different susceptibility to social defeat stress of BalbC and C57BL6/J mice

(2010) Maria Razzoli et al.   BEHAVIOURAL BRAIN RESEARCH

Microglia Shape Adult Hippocampal Neurogenesis through Apoptosis-Coupled Phagocytosis

(2010) Amanda Sierra et al.   Cell Stem Cell

Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues

(2010) Viktor Lakics et al.   NEUROPHARMACOLOGY

Strain-specific outcomes of repeated social defeat and chronic fluoxetine treatment in the mouse

(2010) Maria Razzoli et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Early-life stress and antidepressants modulate peripheral biomarkers in a gene–environment rat model of depression

(2010) Lucia Carboni et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Vulnerability to chronic subordination stress-induced depression-like disorders in adult 129SvEv male mice

(2010) Harold Dadomo et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Hippocampal NMDA receptors and anxiety: At the interface between cognition and emotion

(2009) Christopher Barkus et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: Implications for depression and antidepressant action☆

(2009) P.J. Lucassen et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Interleukin-1 receptor null mutant mice show decreased anxiety-like behavior and enhanced fear memory

(2009) Ja Wook Koo et al.   NEUROSCIENCE LETTERS

ROLE OF TOLL-LIKE RECEPTORS 2 AND 4, AND THE RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS IN HIGH-MOBILITY GROUP BOX 1-INDUCED INFLAMMATION IN VIVO

(2009) Marieke A.D. van Zoelen et al.   SHOCK

A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression

(2008) André Russowsky Brunoni et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes

(2008) T. Yoshizaki et al.   MOLECULAR AND CELLULAR BIOLOGY

Targeting Nuclear Factor- B Activation Pathway by Thymoquinone: Role in Suppression of Antiapoptotic Gene Products and Enhancement of Apoptosis

(2008) G. Sethi et al.   MOLECULAR CANCER RESEARCH

IL-1 is an essential mediator of the antineurogenic and anhedonic effects of stress

(2008) J. W. Koo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of compassion meditation on neuroendocrine, innate immune and behavioral responses to psychosocial stress

(2008) Thaddeus W.W. Pace et al.   PSYCHONEUROENDOCRINOLOGY

Acute Stress Induces Proinflammatory Signaling at Chronic Inflammation Sites

(2008) Ulrike Weik et al.   PSYCHOSOMATIC MEDICINE

The HPA axis in major depression: classical theories and new developments

(2008) Carmine M. Pariante et al.   TRENDS IN NEUROSCIENCES

Corticosteroid hormones in the central stress response: Quick-and-slow

(2007) E. Ronald de Kloet et al.   FRONTIERS IN NEUROENDOCRINOLOGY