An NT-3-releasing bioscaffold supports the formation of TrkC-modified neural stem cell-derived neural network tissue with efficacy in repairing spinal cord injury

Transneuronal delivery of hyper-interleukin-6 enables functional recovery after severe spinal cord injury in mice

(2021) Marco Leibinger et al.   Nature Communications

A functional scaffold to promote the migration and neuronal differentiation of neural stem/progenitor cells for spinal cord injury repair

(2020) Weiyuan Liu et al.   BIOMATERIALS

Biomimetic 3D-printed scaffolds for spinal cord injury repair

(2019) Jacob Koffler et al.   NATURE MEDICINE

Traumatic Spinal Cord Injury: An Overview of Pathophysiology, Models and Acute Injury Mechanisms

(2019) Arsalan Alizadeh et al.   Frontiers in Neurology

Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord

(2019) Julien Delile et al.   DEVELOPMENT

Restoring autophagic flux attenuates cochlear spiral ganglion neuron degeneration by promoting TFEB nuclear translocation via inhibiting MTOR

(2019) Bin Ye et al.   Autophagy

Functional Multipotency of Stem Cells and Recovery Neurobiology of Injured Spinal Cords

(2019) Yang D. Teng   CELL TRANSPLANTATION

Scrublet: Computational Identification of Cell Doublets in Single-Cell Transcriptomic Data

(2019) Samuel L. Wolock et al.   Cell Systems

Spinal cord repair: advances in biology and technology

(2019) Grégoire Courtine et al.   NATURE MEDICINE

Regeneration of Spinal Cord Connectivity Through Stem Cell Transplantation and Biomaterial Scaffolds

(2019) Hiroyuki Katoh et al.   Frontiers in Cellular Neuroscience

Neurotrophin-3 released from implant of tissue-engineered fibroin scaffolds inhibits inflammation, enhances nerve fiber regeneration, and improves motor function in canine spinal cord injury

(2018) Ge Li et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Dissecting spinal cord regeneration

(2018) Michael V. Sofroniew   NATURE

Restorative effects of human neural stem cell grafts on the primate spinal cord

(2018) Ephron S Rosenzweig et al.   NATURE MEDICINE

NT3-chitosan enables de novo regeneration and functional recovery in monkeys after spinal cord injury

(2018) Jia-Sheng Rao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The spinal ependymal zone as a source of endogenous repair cells across vertebrates

(2018) Catherina G. Becker et al.   PROGRESS IN NEUROBIOLOGY

Required growth facilitators propel axon regeneration across complete spinal cord injury

(2018) Mark A. Anderson et al.   NATURE

Cell transplantation therapy for spinal cord injury

(2017) Peggy Assinck et al.   NATURE NEUROSCIENCE

In retinitis pigmentosa TrkC.T1-dependent vectorial Erk activity upregulates glial TNF-α, causing selective neuronal death

(2017) Alba Galán et al.   Cell Death & Disease

Graft of the NT-3 persistent delivery gelatin sponge scaffold promotes axon regeneration, attenuates inflammation, and induces cell migration in rat and canine with spinal cord injury

(2016) Ge Li et al.   BIOMATERIALS

Transplantation of tissue engineering neural network and formation of neuronal relay into the transected rat spinal cord

(2016) Bi-Qin Lai et al.   BIOMATERIALS

Exogenous Expression of Nt-3 and TrkC Genes in Bone Marrow Stromal Cells Elevated the Survival Rate of the Cells in the Course of Neural Differentiation

(2016) Houri Edalat et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Spinal cord reconstitution with homologous neural grafts enables robust corticospinal regeneration

(2016) Ken Kadoya et al.   NATURE MEDICINE

Repair of spinal cord injury with neuronal relays: From fetal grafts to neural stem cells

(2015) Joseph F. Bonner et al.   BRAIN RESEARCH

Plasticity of Intact Rubral Projections Mediates Spontaneous Recovery of Function after Corticospinal Tract Injury

(2015) C. S. Siegel et al.   JOURNAL OF NEUROSCIENCE

Bridging the injured spinal cord with neural stem cells

(2014) Paul Lu et al.   Neural Regeneration Research

Neurotrophin-3 Stimulates Migration of Mesenchymal Stem Cells Overexpressing TrkC

(2013) Y.F. Chen et al.   CURRENT MEDICINAL CHEMISTRY

SAD Kinases Sculpt Axonal Arbors of Sensory Neurons through Long- and Short-Term Responses to Neurotrophin Signals

(2013) Brendan N. Lilley et al.   NEURON

Long-Distance Growth and Connectivity of Neural Stem Cells after Severe Spinal Cord Injury

(2012) Paul Lu et al.   CELL

Dynamic Microenvironments: The Fourth Dimension

(2012) M. W. Tibbitt et al.   Science Translational Medicine

Postsynaptic TrkC and Presynaptic PTPσ Function as a Bidirectional Excitatory Synaptic Organizing Complex

(2011) Hideto Takahashi et al.   NEURON

Neurons derived from transplanted neural stem cells restore disrupted neuronal circuitry in a mouse model of spinal cord injury

(2010) Masahiko Abematsu et al.   JOURNAL OF CLINICAL INVESTIGATION

Stem Cells for Spinal Cord Repair

(2008) Fanie Barnabé-Heider et al.   Cell Stem Cell

Sustained delivery of NT-3 from lens fiber cells in transgenic mice reveals specificity of neuroprotection in retinal degenerations

(2008) Matthew M. LaVail et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Four-dimensional realistic modeling of pancreatic organogenesis

(2008) Y. Setty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA