Restorative effects of human neural stem cell grafts on the primate spinal cord

Prolonged human neural stem cell maturation supports recovery in injured rodent CNS

(2017) Paul Lu et al.   JOURNAL OF CLINICAL INVESTIGATION

SOX9 Is an Astrocyte-Specific Nuclear Marker in the Adult Brain Outside the Neurogenic Regions

(2017) Wei Sun et al.   JOURNAL OF NEUROSCIENCE

Ependymal cell contribution to scar formation after spinal cord injury is minimal, local and dependent on direct ependymal injury

(2017) Yilong Ren et al.   Scientific Reports

Preclinical Efficacy Failure of Human CNS-Derived Stem Cells for Use in the Pathway Study of Cervical Spinal Cord Injury

(2017) Aileen J. Anderson et al.   Stem Cell Reports

Glial progenitor cell-based treatment of the childhood leukodystrophies

(2016) M. Joana Osorio et al.   EXPERIMENTAL NEUROLOGY

A Unilateral Cervical Spinal Cord Contusion Injury Model in Non-Human Primates (Macaca mulatta)

(2016) Ernesto A. Salegio et al.   JOURNAL OF NEUROTRAUMA

Spinal cord reconstitution with homologous neural grafts enables robust corticospinal regeneration

(2016) Ken Kadoya et al.   NATURE MEDICINE

Low excitatory innervation balances high intrinsic excitability of immature dentate neurons

(2016) Cristina V. Dieni et al.   Nature Communications

Large animal and primate models of spinal cord injury for the testing of novel therapies

(2015) Brian K. Kwon et al.   EXPERIMENTAL NEUROLOGY

Pronounced species divergence in corticospinal tract reorganization and functional recovery after lateralized spinal cord injury favors primates

(2015) Lucia Friedli et al.   Science Translational Medicine

Restoration of skilled locomotion by sprouting corticospinal axons induced by co-deletion of PTEN and SOCS3

(2015) Duo Jin et al.   Nature Communications

Neural Stem Cell Dissemination after Grafting to CNS Injury Sites

(2014) Mark H. Tuszynski et al.   CELL

Characterization of Ectopic Colonies That Form in Widespread Areas of the Nervous System with Neural Stem Cell Transplants into the Site of a Severe Spinal Cord Injury

(2014) O. Steward et al.   JOURNAL OF NEUROSCIENCE

Long-Distance Axonal Growth from Human Induced Pluripotent Stem Cells after Spinal Cord Injury

(2014) Paul Lu et al.   NEURON

Neurite pruning and neuronal cell death: spatial regulation of shared destruction programs

(2013) Maya Maor-Nof et al.   CURRENT OPINION IN NEUROBIOLOGY

PTEN Inhibition to Facilitate Intrinsic Regenerative Outgrowth of Adult Peripheral Axons

(2013) K. J. Christie et al.   JOURNAL OF NEUROSCIENCE

Molecular logic of neocortical projection neuron specification, development and diversity

(2013) Luciano Custo Greig et al.   NATURE REVIEWS NEUROSCIENCE

Derivation of Multivariate Syndromic Outcome Metrics for Consistent Testing across Multiple Models of Cervical Spinal Cord Injury in Rats

(2013) Adam R. Ferguson et al.   PLoS One

Long-Distance Growth and Connectivity of Neural Stem Cells after Severe Spinal Cord Injury

(2012) Paul Lu et al.   CELL

Extensive cell migration, axon regeneration, and improved function with polysialic acid-modified Schwann cells after spinal cord injury

(2012) Mousumi Ghosh et al.   GLIA

Animal Models of Neurologic Disorders: A Nonhuman Primate Model of Spinal Cord Injury

(2012) Yvette S. Nout et al.   Neurotherapeutics

Lumbar Intraspinal Injection of Neural Stem Cells in Patients with Amyotrophic Lateral Sclerosis: Results of a Phase I Trial in 12 Patients

(2012) Jonathan D. Glass et al.   STEM CELLS

Grafted Neural Progenitors Integrate and Restore Synaptic Connectivity across the Injured Spinal Cord

(2011) J. F. Bonner et al.   JOURNAL OF NEUROSCIENCE

Breaking Free of Sample Size Dogma to Perform Innovative Translational Research

(2011) P. Bacchetti et al.   Science Translational Medicine

PTEN deletion enhances the regenerative ability of adult corticospinal neurons

(2010) Kai Liu et al.   NATURE NEUROSCIENCE

Extensive spontaneous plasticity of corticospinal projections after primate spinal cord injury

(2010) Ephron S Rosenzweig et al.   NATURE NEUROSCIENCE

Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in an Early Chronic Spinal coRd Injury NOD-scid Mouse Model

(2010) Desirée L. Salazar et al.   PLoS One

Extensive spinal decussation and bilateral termination of cervical corticospinal projections in rhesus monkeys

(2009) Ephron S. Rosenzweig et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Characterization of a human fetal spinal cord stem cell line, NSI-566RSC, and its induction to functional motoneurons

(2009) Xiufang Guo et al.   Journal of Tissue Engineering and Regenerative Medicine

Combined Intrinsic and Extrinsic Neuronal Mechanisms Facilitate Bridging Axonal Regeneration One Year after Spinal Cord Injury

(2009) Ken Kadoya et al.   NEURON

Reliable Activation of Immature Neurons in the Adult Hippocampus

(2009) Lucas A. Mongiat et al.   PLoS One

Induction of corticospinal regeneration by lentiviral trkB-induced Erk activation

(2009) E. R. Hollis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification ofTmem10/Opalinas an oligodendrocyte enriched gene using expression profiling combined with genetic cell ablation

(2008) Neev Golan et al.   GLIA

Spinal cord injury: plasticity, regeneration and the challenge of translational drug development

(2008) Armin Blesch et al.   TRENDS IN NEUROSCIENCES

Growth factors and combinatorial therapies for CNS regeneration

(2007) Paul Lu et al.   EXPERIMENTAL NEUROLOGY

CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure

(2007) Michael T. Fitch et al.   EXPERIMENTAL NEUROLOGY

Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury

(2007) Gregoire Courtine et al.   NATURE MEDICINE