ATP Suppression by pH-Activated Mitochondria-Targeted Delivery of Nitric Oxide Nanoplatform for Drug Resistance Reversal and Metastasis Inhibition

Metformin-Induced Stromal Depletion to Enhance the Penetration of Gemcitabine-Loaded Magnetic Nanoparticles for Pancreatic Cancer Targeted Therapy

(2020) Haijie Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nitric oxide-induced stromal depletion for improved nanoparticle penetration in pancreatic cancer treatment

(2020) Xiaohui Chen et al.   BIOMATERIALS

Conjugate of Doxorubicin to Albumin‐Binding Peptide Outperforms Aldoxorubicin

(2019) Parisa Yousefpour et al.   Small

Self-assembled green tea polyphenol-based coordination nanomaterials to improve chemotherapy efficacy by inhibition of carbonyl reductase 1

(2019) Lingling Shan et al.   BIOMATERIALS

Gas-Mediated Cancer Bioimaging and Therapy

(2019) Lichan Chen et al.   ACS Nano

Visible-Light-Triggered Self-Reporting Release of Nitric Oxide (NO) for Bacterial Biofilm Dispersal

(2019) Zhiqiang Shen et al.   MACROMOLECULES

Surface Charge Switchable Supramolecular Nanocarriers for Nitric Oxide Synergistic Photodynamic Eradication of Biofilms

(2019) Dengfeng Hu et al.   ACS Nano

Stimuli-Responsive NO Release for On-Demand Gas-Sensitized Synergistic Cancer Therapy

(2018) Wenpei Fan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular Mechanisms of Nitric Oxide in Cancer Progression, Signal Transduction, and Metabolism

(2018) Veena Somasundaram et al.   ANTIOXIDANTS & REDOX SIGNALING

Smart Nanoreactors for pH-Responsive Tumor Homing, Mitochondria-Targeting, and Enhanced Photodynamic-Immunotherapy of Cancer

(2018) Guangbao Yang et al.   NANO LETTERS

Mitochondria-targeted half-sandwich rutheniumII diimine complexes: anticancer and antimetastasis via ROS-mediated signalling

(2018) Zhishan Xu et al.   Inorganic Chemistry Frontiers

Mitochondria- and Lysosomes-Targeted Synergistic Chemo-Photodynamic Therapy Associated with Self-Monitoring by Dual Light-Up Fluorescence

(2018) Xiaohui Chen et al.   ADVANCED FUNCTIONAL MATERIALS

Gas-Generating Nanoplatforms: Material Chemistry, Multifunctionality, and Gas Therapy

(2018) Luodan Yu et al.   ADVANCED MATERIALS

ROS-induced NO generation for gas therapy and sensitizing photodynamic therapy of tumor

(2018) Shuang-Shuang Wan et al.   BIOMATERIALS

Nitric oxide as an all-rounder for enhanced photodynamic therapy: Hypoxia relief, glutathione depletion and reactive nitrogen species generation

(2018) Yongyan Deng et al.   BIOMATERIALS

Tumor-Acidity-Cleavable Maleic Acid Amide (TACMAA): A Powerful Tool for Designing Smart Nanoparticles To Overcome Delivery Barriers in Cancer Nanomedicine

(2018) Jin-Zhi Du et al.   ACCOUNTS OF CHEMICAL RESEARCH

Real-Time Imaging of Free Radicals for Mitochondria-Targeting Hypoxic Tumor Therapy

(2018) Xiao-Qiang Wang et al.   NANO LETTERS

A Novel Self-Assembled Mitochondria-Targeting Protein Nanoparticle Acting as Theranostic Platform for Cancer

(2018) Xin-Jie Zhu et al.   Small

Mitochondrial determinants of cancer health disparities

(2017) Aaheli Roy Choudhury et al.   SEMINARS IN CANCER BIOLOGY

Multistage Targeting Strategy Using Magnetic Composite Nanoparticles for Synergism of Photothermal Therapy and Chemotherapy

(2017) Yi Wang et al.   Small

Peptide-Mediated Delivery of Chemical Probes and Therapeutics to Mitochondria

(2016) Sae Rin Jean et al.   ACCOUNTS OF CHEMICAL RESEARCH

Toward a Better Understanding of the Complexity of Cancer Drug Resistance

(2016) Michael M. Gottesman et al.   Annual Review of Pharmacology and Toxicology

Doxorubicin/heparin composite nanoparticles for caspase-activated prodrug chemotherapy

(2016) Nisar Ul Khaliq et al.   BIOMATERIALS

Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis

(2016) Annette Becker et al.   CANCER CELL

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family in multidrug resistance: A review of the past decade

(2016) Zhaolin Chen et al.   CANCER LETTERS

Mitochondria and Cancer

(2016) Sejal Vyas et al.   CELL

Programmed photosensitizer conjugated supramolecular nanocarriers with dual targeting ability for enhanced photodynamic therapy

(2016) Hongxin Tong et al.   CHEMICAL COMMUNICATIONS

Reversal of doxorubicin resistance in breast cancer by mitochondria-targeted pH-responsive micelles

(2015) Pengcheng Yu et al.   Acta Biomaterialia

Controllable Generation of Nitric Oxide by Near-Infrared-Sensitized Upconversion Nanoparticles for Tumor Therapy

(2015) Xiao Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

Size Changeable Nanocarriers with Nuclear Targeting for Effectively Overcoming Multidrug Resistance in Cancer Therapy

(2015) Xing Guo et al.   ADVANCED MATERIALS

Near-IR mediated intracellular uncaging of NO from cell targeted hollow gold nanoparticles

(2015) Elizabeth S. Levy et al.   CHEMICAL COMMUNICATIONS

Intracellular delivery of nanocarriers and targeting to subcellular organelles

(2015) Aditi Jhaveri et al.   Expert Opinion on Drug Delivery

Mitochondria of a human multidrug-resistant hepatocellular carcinoma cell line constitutively express inducible nitric oxide synthase in the inner membrane

(2015) Ornella Fantappiè et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis

(2014) T. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preparation of a Mitochondria-targeted and NO-Releasing Nanoplatform and its Enhanced Pro-Apoptotic Effect on Cancer Cells

(2014) Jiangsheng Xu et al.   Small

Mitochondrial-Targeting Nitrooxy-doxorubicin: A New Approach To Overcome Drug Resistance

(2012) Chiara Riganti et al.   MOLECULAR PHARMACEUTICS

Tailor-Made Dual pH-Sensitive Polymer–Doxorubicin Nanoparticles for Efficient Anticancer Drug Delivery

(2011) Jin-Zhi Du et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Subcellular targeting strategies for drug design and delivery

(2009) Lawrence Rajendran et al.   NATURE REVIEWS DRUG DISCOVERY