Toxicometabolomics: Small Molecules to Answer Big Toxicological Questions
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Title
Toxicometabolomics: Small Molecules to Answer Big Toxicological Questions
Authors
Keywords
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Journal
Metabolites
Volume 11, Issue 10, Pages 692
Publisher
MDPI AG
Online
2021-10-11
DOI
10.3390/metabo11100692
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Note: Only part of the references are listed.- A Novel Tool to Screen for Treatments with Clenbuterol in Bovine: Identification of two Hepatic Markers by Metabolomics Investigation
- (2021) Roberto Stella et al. FOOD CHEMISTRY
- Applications of Metabolomics in Forensic Toxicology and Forensic Medicine
- (2021) Michal Szeremeta et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cell metabolomics analyses revealed a role of altered fatty acid oxidation in neurotoxicity pattern difference between nab-paclitaxel and solvent-based paclitaxel
- (2021) Jhih-Wei Huang et al. PLoS One
- Urinary metabolic characterization with nephrotoxicity for residents under cadmium exposure
- (2021) Ting Zeng et al. ENVIRONMENT INTERNATIONAL
- 3,4-Methylenedioxymethamphetamine Hepatotoxicity under the Heat Stress Condition: Novel Insights from in Vitro Metabolomic Studies
- (2020) Ana Margarida Araújo et al. JOURNAL OF PROTEOME RESEARCH
- A Targeted Metabolomics-Based Assay Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Identifies Structural and Functional Cardiotoxicity Potential
- (2020) Jessica A Palmer et al. TOXICOLOGICAL SCIENCES
- Data-dependent normalization strategies for untargeted metabolomics—a case study
- (2020) Paula Cuevas-Delgado et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Important Considerations for Sample Collection in Metabolomics Studies with a Special Focus on Applications to Liver Functions
- (2020) Lorraine Smith et al. Metabolites
- Toxicology of tramadol following chronic exposure based on metabolomics of the cerebrum in mice
- (2020) Wei Xia et al. Scientific Reports
- Metabolomic analysis of primary human skeletal muscle cells during myogenic progression
- (2020) Ashok Kumar et al. Scientific Reports
- Recommendations and Best Practices for Standardizing the Pre-Analytical Processing of Blood and Urine Samples in Metabolomics
- (2020) Raúl González-Domínguez et al. Metabolites
- In vivo toxicometabolomics reveals multi-organ and urine metabolic changes in mice upon acute exposure to human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV)
- (2020) Ana Margarida Araújo et al. ARCHIVES OF TOXICOLOGY
- Exploration the Mechanism of Doxorubicin-Induced Heart Failure in Rats by Integration of Proteomics and Metabolomics Data
- (2020) Yu Yuan et al. Frontiers in Pharmacology
- The use of solid phase microextraction for metabolomic analysis of non-small cell lung carcinoma cell line (A549) after administration of combretastatin A4
- (2019) Karol Jaroch et al. Scientific Reports
- Validated comprehensive metabolomics and lipidomics analysis of colon tissue and cell lines
- (2019) Caroline Rombouts et al. ANALYTICA CHIMICA ACTA
- Metabolomic Strategies in Biomarker Research–New Approach for Indirect Identification of Drug Consumption and Sample Manipulation in Clinical and Forensic Toxicology?
- (2019) Andrea E. Steuer et al. Frontiers in Chemistry
- Application of metabolomics to characterize environmental pollutant toxicity and disease risks
- (2019) Pan Deng et al. REVIEWS ON ENVIRONMENTAL HEALTH
- Metabolomic profiles of induced pluripotent stem cells derived from patients with rheumatoid arthritis and osteoarthritis
- (2019) Juryun Kim et al. Stem Cell Research & Therapy
- Assessment of the effects of metribuzin, glyphosate, and their mixtures on the metabolism of the model plant Lemna minor L. applying metabolomics
- (2019) Sofia Kostopoulou et al. CHEMOSPHERE
- Analytical techniques for metabolomic studies: a review
- (2019) Karen Segers et al. Bioanalysis
- The influence of culture media upon observed cell secretome metabolite profiles: The balance between cell viability and data interpretability
- (2018) Evangelia Daskalaki et al. ANALYTICA CHIMICA ACTA
- Evaluation of two-step liquid-liquid extraction protocol for untargeted metabolic profiling of serum samples to achieve broader metabolome coverage by UPLC-Q-TOF-MS
- (2018) Rui Liu et al. ANALYTICA CHIMICA ACTA
- Metabolomics of Hydrazine-Induced Hepatotoxicity in Rats for Discovering Potential Biomarkers
- (2018) Zhuoling An et al. DISEASE MARKERS
- Food safety using NMR-based metabolomics: Assessment of the Atlantic bluefin tuna, Thunnus thynnus , from the Mediterranean Sea
- (2018) Tiziana Cappello et al. FOOD AND CHEMICAL TOXICOLOGY
- Effects of long-term cadmium exposure on urinary metabolite profiles in mice
- (2018) Sailendra Nath Sarma et al. JOURNAL OF TOXICOLOGICAL SCIENCES
- Serum and urine toxicometabolomics following gentamicin-induced nephrotoxicity in male Sprague-Dawley rats
- (2018) Sung Ha Ryu et al. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES
- MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis
- (2018) Jasmine Chong et al. NUCLEIC ACIDS RESEARCH
- Metabolomic assessment of arsenite toxicity and novel biomarker discovery in early development of zebrafish embryos
- (2018) Szu-Yuan Wu et al. TOXICOLOGY LETTERS
- Advances in mass spectrometry-based metabolomics for investigation of metabolites
- (2018) Jun-Ling Ren et al. RSC Advances
- Metabolomics in chronic kidney disease: Strategies for extended metabolome coverage
- (2018) Gagnebin Yoric et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- An improved method for extraction of polar and charged metabolites from cyanobacteria
- (2018) Charulata B. Prasannan et al. PLoS One
- Novel technologies for metabolomics: More for less
- (2018) Paul Miggiels et al. TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- The metabolic programming of stem cells
- (2017) Ng Shyh-Chang et al. GENES & DEVELOPMENT
- Potential neurotoxicity of prenatal exposure to sevoflurane on offspring: Metabolomics investigation on neurodevelopment and underlying mechanism
- (2017) Jialong Jiang et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- Untargeted metabolomics of neuronal cell culture: A model system for the toxicity testing of insecticide chemical exposure
- (2017) Sarah Hayton et al. JOURNAL OF APPLIED TOXICOLOGY
- High-throughput extraction and quantification method for targeted metabolomics in murine tissues
- (2017) Sven Zukunft et al. Metabolomics
- Biochemical effects of venlafaxine on astrocytes as revealed by 1H NMR-based metabolic profiling
- (2017) Lu Sun et al. Molecular BioSystems
- The MetaCyc database of metabolic pathways and enzymes
- (2017) Ron Caspi et al. NUCLEIC ACIDS RESEARCH
- HMDB 4.0: the human metabolome database for 2018
- (2017) David S Wishart et al. NUCLEIC ACIDS RESEARCH
- Systematic evaluation of serum and plasma collection on the endogenous metabolome
- (2017) Zhi Zhou et al. Bioanalysis
- Metabolomics for the early detection of cisplatin-induced nephrotoxicity
- (2017) Takeshi Ezaki et al. Toxicology Research
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- (2017) Kenneth A. Dyar Frontiers in Neuroscience
- Human embryonic and induced pluripotent stem cells maintain phenotype but alter their metabolism after exposure to ROCK inhibitor
- (2017) Spyros I. Vernardis et al. Scientific Reports
- 21st Century Cell Culture for 21st Century Toxicology
- (2016) David Pamies et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Sample normalization methods in quantitative metabolomics
- (2016) Yiman Wu et al. JOURNAL OF CHROMATOGRAPHY A
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- (2016) Jia Yin et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Metabolomics studies in brain tissue: A review
- (2016) Carolina Gonzalez-Riano et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- The metabolome 18 years on: a concept comes of age
- (2016) Douglas B. Kell et al. Metabolomics
- KEGG: new perspectives on genomes, pathways, diseases and drugs
- (2016) Minoru Kanehisa et al. NUCLEIC ACIDS RESEARCH
- A metabolomics cell-based approach for anticipating and investigating drug-induced liver injury
- (2016) Juan Carlos García- Cañaveras et al. Scientific Reports
- Environmental metabolomics: Biological markers for metal toxicity
- (2015) Miguel Ángel García-Sevillano et al. ELECTROPHORESIS
- Can NMR solve some significant challenges in metabolomics?
- (2015) G.A. Nagana Gowda et al. JOURNAL OF MAGNETIC RESONANCE
- Screening, Verification, and Optimization of Biomarkers for Early Prediction of Cardiotoxicity Based on Metabolomics
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- Defining the Metabolome: Size, Flux, and Regulation
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- (2015) Bin Liu et al. NEUROCHEMICAL RESEARCH
- Whole Blood Reveals More Metabolic Detail of the Human Metabolome than Serum as Measured by 1H-NMR Spectroscopy
- (2015) Kathleen A. Stringer et al. SHOCK
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- (2015) Katherine A. Overmyer et al. PLoS One
- Metabolomics in cell culture—A strategy to study crucial metabolic pathways in cancer development and the response to treatment
- (2014) Anna Halama ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Brain Region Mapping Using Global Metabolomics
- (2014) Julijana Ivanisevic et al. CHEMISTRY & BIOLOGY
- An effective assessment of valproate sodium-induced hepatotoxicity with UPLC–MS and 1HNMR-based metabonomics approach
- (2014) Taoguang Huo et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Potential of metabolomics in preclinical and clinical drug development
- (2014) Baldeep Kumar et al. Pharmacological Reports
- Evaluating solvent extraction systems using metabolomics approaches
- (2014) Amanda C. Martin et al. RSC Advances
- Identification of a metabolic biomarker panel in rats for prediction of acute and idiosyncratic hepatotoxicity
- (2014) Jinchun Sun et al. Computational and Structural Biotechnology Journal
- Measurement of DNA Concentration as a Normalization Strategy for Metabolomic Data from Adherent Cell Lines
- (2013) Leslie P. Silva et al. ANALYTICAL CHEMISTRY
- The impact of blood on liver metabolite profiling - a combined metabolomic and proteomic approach
- (2013) Saray Ly-Verdú et al. BIOMEDICAL CHROMATOGRAPHY
- Mammalian cell metabolomics: Experimental design and sample preparation
- (2013) Zacarías León et al. ELECTROPHORESIS
- Review: Toxicometabolomics
- (2013) Mounir Bouhifd et al. JOURNAL OF APPLIED TOXICOLOGY
- Trials and tribulations of ‘omics data analysis: assessing quality of SIMCA-based multivariate models using examples from pulmonary medicine
- (2013) Åsa M. Wheelock et al. Molecular BioSystems
- Urinary metabolomic markers of aminoglycoside nephrotoxicity in newborn rats
- (2013) Mina H. Hanna et al. PEDIATRIC RESEARCH
- LC-MS-BASED METABOLOMICS OF XENOBIOTIC-INDUCED TOXICITIES
- (2013) Chi Chen et al. Computational and Structural Biotechnology Journal
- SPECTRAL DECONVOLUTION FOR GAS CHROMATOGRAPHY MASS SPECTROMETRY-BASED METABOLOMICS: CURRENT STATUS AND FUTURE PERSPECTIVES
- (2013) Xiuxia Du et al. Computational and Structural Biotechnology Journal
- NMR and pattern recognition methods in metabolomics: From data acquisition to biomarker discovery: A review
- (2012) Agnieszka Smolinska et al. ANALYTICA CHIMICA ACTA
- XCMS Online: A Web-Based Platform to Process Untargeted Metabolomic Data
- (2012) Ralf Tautenhahn et al. ANALYTICAL CHEMISTRY
- Biotransformation of diclofenac and effects on the metabolome of primary human hepatocytes upon repeated dose exposure
- (2012) Daniel Mueller et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Global metabolic profiling of animal and human tissues via UPLC-MS
- (2012) Elizabeth J Want et al. Nature Protocols
- The Emerging Field of Quantitative Blood Metabolomics for Biomarker Discovery in Critical Illnesses
- (2011) Natalie J. Serkova et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Monitoring metabolites consumption and secretion in cultured cells using ultra-performance liquid chromatography quadrupole–time of flight mass spectrometry (UPLC–Q–ToF-MS)
- (2011) Giuseppe Paglia et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Xenobiotic Metabolomics: Major Impact on the Metabolome
- (2011) Caroline H. Johnson et al. Annual Review of Pharmacology and Toxicology
- An untargeted multi-technique metabolomics approach to studying intracellular metabolites of HepG2 cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin
- (2011) Ainhoa Ruiz-Aracama et al. BMC GENOMICS
- Microbial Metabolomics
- (2011) Jane Tang CURRENT GENOMICS
- Recent and potential developments of biofluid analyses in metabolomics
- (2011) Aihua Zhang et al. Journal of Proteomics
- Bioinformatics tools for cancer metabolomics
- (2011) Grigoriy Blekherman et al. Metabolomics
- MetAlign 3.0: performance enhancement by efficient use of advances in computer hardware
- (2011) Arjen Lommen et al. Metabolomics
- Metabolite extraction from suspension-cultured mammalian cells for global metabolite profiling
- (2011) Christopher A Sellick et al. Nature Protocols
- Global urinary metabolic profiling procedures using gas chromatography–mass spectrometry
- (2011) Eric Chun Yong Chan et al. Nature Protocols
- Metabolomics in the study of kidney diseases
- (2011) Robert H. Weiss et al. Nature Reviews Nephrology
- Differences between Human Plasma and Serum Metabolite Profiles
- (2011) Zhonghao Yu et al. PLoS One
- Multivariate methods in metabolomics – from pre-processing to dimension reduction and statistical analysis
- (2011) Kristian Hovde Liland TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- Data-processing strategies for metabolomics studies
- (2011) Margriet M.W.B. Hendriks et al. TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- Development and optimization of a metabolomic method for analysis of adherent cell cultures
- (2010) Anders P.H. Danielsson et al. ANALYTICAL BIOCHEMISTRY
- Metabolomics—The State of Art
- (2010) A. Krastanov BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT
- MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data
- (2010) Tomáš Pluskal et al. BMC BIOINFORMATICS
- Applications of liquid chromatography coupled to mass spectrometry-based metabolomics in clinical chemistry and toxicology: A review
- (2010) Aurélie Roux et al. CLINICAL BIOCHEMISTRY
- Cell culture metabolomics: applications and future directions
- (2010) Miroslava Čuperlović-Culf et al. DRUG DISCOVERY TODAY
- Data-Driven Optimization of Metabolomics Methods Using Rat Liver Samples
- (2009) Gauri S. Parab et al. ANALYTICAL CHEMISTRY
- What is metabolomics all about?
- (2009) Ute Roessner et al. BIOTECHNIQUES
- Analytical and statistical approaches to metabolomics research
- (2009) Haleem J. Issaq et al. JOURNAL OF SEPARATION SCIENCE
- The complex links between dietary phytochemicals and human health deciphered by metabolomics
- (2009) Claudine Manach et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Metabonomic identification of novel biomarkers in doxorubicin cardiotoxicity and protective effect of the natural antioxidant oleuropein
- (2009) Ioanna Andreadou et al. NMR IN BIOMEDICINE
- SMPDB: The Small Molecule Pathway Database
- (2009) Alex Frolkis et al. NUCLEIC ACIDS RESEARCH
- Two-dimensional J-resolved NMR spectroscopy: review of a key methodology in the metabolomics toolbox
- (2009) Christian Ludwig et al. PHYTOCHEMICAL ANALYSIS
- Discovery of Metabolomics Biomarkers for Early Detection of Nephrotoxicity
- (2009) Kurt J. Boudonck et al. TOXICOLOGIC PATHOLOGY
- Are In Vitro Tests Suitable for Regulatory Use?
- (2009) Thomas Hartung et al. TOXICOLOGICAL SCIENCES
- Metabolomics approaches for discovering biomarkers of drug-induced hepatotoxicity and nephrotoxicity
- (2009) Richard D. Beger et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Metabolomics
- (2008) V. Gomase et al. CURRENT DRUG METABOLISM
- Metabolomics and fluxomics approaches
- (2008) Marta Cascante et al. Essays in Biochemistry
- Instrumental and experimental effects in LC–MS-based metabolomics
- (2008) Lyle Burton et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- A direct cell quenching method for cell-culture based metabolomics
- (2008) Quincy Teng et al. Metabolomics
- Assessment of PLSDA cross validation
- (2008) Johan A. Westerhuis et al. Metabolomics
- Evidence of different metabolic phenotypes in humans
- (2008) M. Assfalg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A novel in vitro metabolomics approach for neurotoxicity testing, proof of principle for methyl mercury chloride and caffeine
- (2007) Erwin van Vliet et al. NEUROTOXICOLOGY
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