Important Considerations for Sample Collection in Metabolomics Studies with a Special Focus on Applications to Liver Functions

Integrated Plasma and Bile Metabolomics Based on an UHPLC-Q/TOF-MS and Network Pharmacology Approach to Explore the Potential Mechanism of Schisandra chinensis-Protection From Acute Alcoholic Liver Injury

(2020) Lianlin Su et al.   Frontiers in Pharmacology

Fructose malabsorption induces cholecystokinin expression in the ileum and cecum by changing microbiota composition and metabolism

(2019) Xufei Zhang et al.   FASEB JOURNAL

Past, present and future perspectives in nonalcoholic fatty liver disease

(2019) Arun J. Sanyal   Nature Reviews Gastroenterology & Hepatology

Pre-Analytical Factors that Affect Metabolite Stability in Human Urine, Plasma, and Serum: A Review

(2019) Victoria L. Stevens et al.   Metabolites

Risk profiling using metabolomic characteristics for susceptible individuals of drug-induced liver injury caused by Polygonum multiflorum

(2019) Le Zhang et al.   ARCHIVES OF TOXICOLOGY

Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF

(2019) Richard Moreau et al.   JOURNAL OF HEPATOLOGY

Metabolic Signature of Hepatic Fibrosis: From Individual Pathways to Systems Biology

(2019) Ming-Ling Chang et al.   Cells

Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor

(2019) Céline Lukowicz et al.   Scientific Reports

Single Spheroid Metabolomics: Optimizing Sample Preparation of Three-Dimensional Multicellular Tumor Spheroids

(2019) Mate Rusz et al.   Metabolites

A review on human fecal metabolomics: Methods, applications and the human fecal metabolome database

(2018) Naama Karu et al.   ANALYTICA CHIMICA ACTA

Short-Term Fasting Reveals Amino Acid Metabolism as a Major Sex-Discriminating Factor in the Liver

(2018) Sara Della Torre et al.   Cell Metabolism

Metabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor

(2018) Céline Lukowicz et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The fecal metabolome as a functional readout of the gut microbiome

(2018) Jonas Zierer et al.   NATURE GENETICS

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

(2018) Lesley Hoyles et al.   NATURE MEDICINE

Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors

(2018) Jonathan M. Weiss et al.   JOURNAL OF CLINICAL INVESTIGATION

An Untargeted Metabolomics Approach to Investigate the Metabolic Modulations of HepG2 Cells Exposed to Low Doses of Bisphenol A and 17β-Estradiol

(2018) Nicolas J. Cabaton et al.   Frontiers in Endocrinology

Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1

(2018) Ara Koh et al.   CELL

Large-Scale Modeling Approach Reveals Functional Metabolic Shifts during Hepatic Differentiation

(2018) Nathalie Poupin et al.   JOURNAL OF PROTEOME RESEARCH

Serotonin signals through a gut-liver axis to regulate hepatic steatosis

(2018) Wonsuk Choi et al.   Nature Communications

Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease

(2017) Chris Estes et al.   HEPATOLOGY

The liver-gut microbiota axis modulates hepatotoxicity of tacrine in the rat

(2017) Lian Yee Yip et al.   HEPATOLOGY

Tributyl phosphate impairs the urea cycle and alters liver pathology and metabolism in mice after short-term exposure based on a metabonomics study

(2017) Lili Zhou et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Hepatic Dysfunction Caused by Consumption of a High-Fat Diet

(2017) Anthony R. Soltis et al.   Cell Reports

Metabolomic analysis—Addressing NMR and LC-MS related problems in human feces sample preparation

(2017) Simon Moosmang et al.   CLINICA CHIMICA ACTA

Optimized Sample Handling Strategy for Metabolic Profiling of Human Feces

(2016) Jasmine Gratton et al.   ANALYTICAL CHEMISTRY

Comparison of Collection Methods for Fecal Samples for Discovery Metabolomics in Epidemiologic Studies

(2016) E. Loftfield et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism

(2016) Thibaut Duparc et al.   GUT

The association of fecal microbiota and fecal, blood serum and urine metabolites in myalgic encephalomyelitis/chronic fatigue syndrome

(2016) Christopher W. Armstrong et al.   Metabolomics

Signals from the gut microbiota to distant organs in physiology and disease

(2016) Bjoern O Schroeder et al.   NATURE MEDICINE

Metabolomics of fecal samples: A practical consideration

(2016) Silke Matysik et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals

(2016) Alexandra Montagner et al.   Scientific Reports

Effects of pre-analytical processes on blood samples used in metabolomics studies

(2015) Peiyuan Yin et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Strategy for Nuclear-Magnetic-Resonance-Based Metabolomics of Human Feces

(2015) Santosh Lamichhane et al.   ANALYTICAL CHEMISTRY

Effects of Diurnal Variation of Gut Microbes and High-Fat Feeding on Host Circadian Clock Function and Metabolism

(2015) Vanessa Leone et al.   Cell Host & Microbe

The Characterization of Feces and Urine: A Review of the Literature to Inform Advanced Treatment Technology

(2015) C. Rose et al.   CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY

Comparative Circadian Metabolomics Reveal Differential Effects of Nutritional Challenge in the Serum and Liver

(2015) Serena Abbondante et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolomics of adherent mammalian cells by capillary electrophoresis-mass spectrometry: HT-29 cells as case study

(2015) Clara Ibáñez et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Alterations in Human Liver Metabolome during Prolonged Cryostorage

(2015) Peter M. Abuja et al.   JOURNAL OF PROTEOME RESEARCH

Metabolomic Analysis of Human Fecal Microbiota: A Comparison of Feces-Derived Communities and Defined Mixed Communities

(2015) Sandi Yen et al.   JOURNAL OF PROTEOME RESEARCH

Tissue sample stability: thawing effect on multi-organ samples

(2015) Frida Torell et al.   Metabolomics

Rhythmicity of the intestinal microbiota is regulated by gender and the host circadian clock

(2015) Xue Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human plasma stability during handling and storage: impact on NMR metabolomics

(2014) Joana Pinto et al.   ANALYST

UPLC-ESI-QTOF/MS and multivariate data analysis for blood plasma and serum metabolomics: Effect of experimental artefacts and anticoagulant

(2013) Thaer Barri et al.   ANALYTICA CHIMICA ACTA

Mammalian cell metabolomics: Experimental design and sample preparation

(2013) Zacarías León et al.   ELECTROPHORESIS

Global gas chromatography/time-of-flight mass spectrometry (GC/TOFMS)-based metabonomic profiling of lyophilized human feces

(2013) Lee Cheng Phua et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

The Approach to Sample Acquisition and Its Impact on the Derived Human Fecal Microbiome and VOC Metabolome

(2013) Robin D. Couch et al.   PLoS One

Nutrimetabonomics:Applications for Nutritional Sciences, with Specific Reference to Gut Microbial Interactions

(2013) Sandrine P. Claus et al.   Annual Review of Food Science and Technology

Subsecond Absolute Quantitation of Amine Metabolites Using Isobaric Tags for Discovery of Pathway Activation in Mammalian Cells

(2012) Wei Yuan et al.   ANALYTICAL CHEMISTRY

Quantification of homocysteine-related metabolites and the role of betaine-homocysteineS-methyltransferase in HepG2 cells

(2012) Marek Kořínek et al.   BIOMEDICAL CHROMATOGRAPHY

Preexisting epithelial diversity in normal human livers: A tissue-tethered cytometric analysis in portal/periportal epithelial cells

(2012) Kumiko Isse et al.   HEPATOLOGY

Metabolomics reveals an essential role for peroxisome proliferator-activated receptor α in bile acid homeostasis

(2012) Fei Li et al.   JOURNAL OF LIPID RESEARCH

Metabonomic Profiling of TASTPM Transgenic Alzheimer’s Disease Mouse Model

(2012) Ze-Ping Hu et al.   JOURNAL OF PROTEOME RESEARCH

Global metabolic profiling of animal and human tissues via UPLC-MS

(2012) Elizabeth J Want et al.   Nature Protocols

The human circadian metabolome

(2012) R. Dallmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preparation of urine samples prior to targeted or untargeted metabolomics mass-spectrometry analysis

(2012) M.A. Fernández-Peralbo et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Reducing Time and Increasing Sensitivity in Sample Preparation for Adherent Mammalian Cell Metabolomics

(2011) Matthew A. Lorenz et al.   ANALYTICAL CHEMISTRY

Metabolomic and Transcriptomic Changes Induced by Overnight (16 h) Fasting in Male and Female Sprague−Dawley Rats

(2011) Donald G. Robertson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Standard operating procedures for pre-analytical handling of blood and urine for metabolomic studies and biobanks

(2011) Patrizia Bernini et al.   JOURNAL OF BIOMOLECULAR NMR

Circadian rhythms, sleep, and metabolism

(2011) Wenyu Huang et al.   JOURNAL OF CLINICAL INVESTIGATION

Metabolomics of Fecal Extracts Detects Altered Metabolic Activity of Gut Microbiota in Ulcerative Colitis and Irritable Bowel Syndrome

(2011) Gwénaëlle Le Gall et al.   JOURNAL OF PROTEOME RESEARCH

Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry

(2011) Warwick B Dunn et al.   Nature Protocols

Metabolite extraction from adherently growing mammalian cells for metabolomics studies: optimization of harvesting and extraction protocols

(2010) Katja Dettmer et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Characterization of Differences between Blood Sample Matrices in Untargeted Metabolomics

(2010) Judith R. Denery et al.   ANALYTICAL CHEMISTRY

Constitutive androstane receptor activation stimulates faecal bile acid excretion and reverse cholesterol transport in mice

(2010) Anne Laure Sberna et al.   JOURNAL OF HEPATOLOGY

Plasma metabolomic profile in nonalcoholic fatty liver disease

(2010) Satish C. Kalhan et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Metabolomics reveals a novel vitamin E metabolite and attenuated vitamin E metabolism upon PXR activation

(2009) Joo-Youn Cho et al.   JOURNAL OF LIPID RESEARCH

MR metabolomics of fecal extracts: applications in the study of bowel diseases

(2009) Tedros Bezabeh et al.   MAGNETIC RESONANCE IN CHEMISTRY

Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism

(2009) T. A. Clayton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD+ Biosynthesis

(2009) K. M. Ramsey et al.   SCIENCE

Harmonics of Circadian Gene Transcription in Mammals

(2009) Michael E. Hughes et al.   PLoS Genetics

Liquid chromatography and ultra-performance liquid chromatography–mass spectrometry fingerprinting of human urine

(2007) Helen G. Gika et al.   JOURNAL OF CHROMATOGRAPHY A

Species Variation in the Fecal Metabolome Gives Insight into Differential Gastrointestinal Function

(2007) Jasmina Saric et al.   JOURNAL OF PROTEOME RESEARCH