Trials and tribulations of ‘omics data analysis: assessing quality of SIMCA-based multivariate models using examples from pulmonary medicine

Lipid mediator profiles differ between lung compartments in asthmatic and healthy humans

(2013) N. Larsson et al.   EUROPEAN RESPIRATORY JOURNAL

Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients

(2013) Bettina Levänen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Building Multivariate Systems Biology Models

(2012) Gemma M. Kirwan et al.   ANALYTICAL CHEMISTRY

Chemometrics

(2012) Barry K. Lavine et al.   ANALYTICAL CHEMISTRY

Toward Systems Biology of Pulmonary Hypertension

(2012) Ferhaan Ahmad et al.   CIRCULATION

Quantitative intact proteomics investigations of alveolar macrophages in sarcoidosis

(2012) Ernesto Silva et al.   EUROPEAN RESPIRATORY JOURNAL

Gender differences in the bronchoalveolar lavage cell proteome of patients with chronic obstructive pulmonary disease

(2012) Maxie Kohler et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Advantages of orthogonal inspection in chemometrics

(2012) Rui Climaco Pinto et al.   JOURNAL OF CHEMOMETRICS

Targeted metabolomics identifies perturbations in amino acid metabolism that sub-classify patients with COPD

(2012) Baljit K. Ubhi et al.   Molecular BioSystems

MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis

(2012) J. Xia et al.   NUCLEIC ACIDS RESEARCH

Integrative systems biology approaches in asthma pharmacogenomics

(2012) Amber Dahlin et al.   PHARMACOGENOMICS

Allergic Asthmatics Show Divergent Lipid Mediator Profiles from Healthy Controls Both at Baseline and following Birch Pollen Provocation

(2012) Susanna L. Lundström et al.   PLoS One

Ten Years of Pathway Analysis: Current Approaches and Outstanding Challenges

(2012) Purvesh Khatri et al.   PLoS Computational Biology

New insights into asthma pathogenesis and treatment

(2011) Stanley J Szefler et al.   CURRENT OPINION IN IMMUNOLOGY

The False-positive to False-negative Ratio in Epidemiologic Studies

(2011) John P. A. Ioannidis et al.   EPIDEMIOLOGY

Metabolic profiling detects biomarkers of protein degradation in COPD patients

(2011) Baljit K. Ubhi et al.   EUROPEAN RESPIRATORY JOURNAL

Metabolomic profiling of asthma: Diagnostic utility of urine nuclear magnetic resonance spectroscopy

(2011) Erik J. Saude et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Asthmatics Exhibit Altered Oxylipin Profiles Compared to Healthy Individuals after Subway Air Exposure

(2011) Susanna L. Lundström et al.   PLoS One

Addressing the Complexity of Chronic Obstructive Pulmonary Disease

(2010) Alvar Agusti et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

An Integrative Systems Biology Approach to Understanding Pulmonary Diseases

(2010) Charles Auffray et al.   CHEST

Clinical COPD phenotypes: a novel approach using principal component and cluster analyses

(2010) P.-R. Burgel et al.   EUROPEAN RESPIRATORY JOURNAL

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

(2010)   NATURE BIOTECHNOLOGY

Chemometrics in metabolomics—A review in human disease diagnosis

(2009) Rasmus Madsen et al.   ANALYTICA CHIMICA ACTA

Discriminating pulmonary hypertension caused by monocrotaline toxicity from chronic hypoxia by near-infrared spectroscopy and multivariate methods of analysis

(2009) Simon Duri et al.   ANALYTICAL BIOCHEMISTRY

OPLS filtered data can be obtained directly from non-orthogonalized PLS1

(2009) E. K. Kemsley et al.   JOURNAL OF CHEMOMETRICS

The use of network analyses for elucidating mechanisms in cardiovascular disease

(2009) Diego Diez et al.   Molecular BioSystems

Qualitative aspects of breathlessness in health and disease

(2009) J Smith et al.   THORAX

Quantification of dyspnoea using descriptors: development and initial testing of the Dyspnoea-12

(2009) J Yorke et al.   THORAX

Notes on the practical utility of OPLS

(2009) Henri S. Tapp et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Chronic lung diseases

(2009) Wei Wu et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Metabolomic Biomarkers in a Model of Asthma Exacerbation

(2008) Erik J. Saude et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

CV-ANOVA for significance testing of PLS and OPLS® models

(2008) Lennart Eriksson et al.   JOURNAL OF CHEMOMETRICS

Visualization of GC/TOF-MS-Based Metabolomics Data for Identification of Biochemically Interesting Compounds Using OPLS Class Models

(2007) Susanne Wiklund et al.   ANALYTICAL CHEMISTRY