Mutators Enhance Adaptive Micro-Evolution in Pathogenic Microbes

Rapid molecular evolution of Spiroplasma symbionts of Drosophila

(2021) Michael Gerth et al.   Microbial Genomics

Genomic and phenotypic diversity of Enterococcus faecalis isolated from endophthalmitis

(2021) Gayatri Shankar Chilambi et al.   PLoS One

Examination of gene loss in the DNA mismatch repair pathway and its mutational consequences in a fungal phylum

(2021) Megan A Phillips et al.   Genome Biology and Evolution

Prevalence of hypermutator isolates of Achromobacter spp. from cystic fibrosis patients

(2020) Winnie Ridderberg et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

5-fluorocytosine resistance is associated with hypermutation and alterations in capsule biosynthesis in Cryptococcus

(2020) R. Blake Billmyre et al.   Nature Communications

Hypermutation as an Evolutionary Mechanism for Achromobacter xylosoxidans in Cystic Fibrosis Lung Infection

(2020) Laura Veschetti et al.   Pathogens

Divergent Evolution of Mutation Rates and Biases in the Long-Term Evolution Experiment with Escherichia coli

(2020) Rohan Maddamsetti et al.   Genome Biology and Evolution

A Novel, Drug Resistance-Independent, Fluorescence-Based Approach To Measure Mutation Rates in Microbial Pathogens

(2019) Erika Shor et al.   mBio

Lighting Up Mutation: a New Unbiased System for the Measurement of Microbial Mutation Rates

(2019) Kylie J. Boyce et al.   mBio

Extensive loss of cell-cycle and DNA repair genes in an ancient lineage of bipolar budding yeasts

(2019) Jacob L. Steenwyk et al.   PLOS BIOLOGY

Dynamic Emergence of Mismatch Repair Deficiency Facilitates Rapid Evolution of Ceftazidime-Avibactam Resistance in Pseudomonas aeruginosa Acute Infection

(2019) Pavel P. Khil et al.   mBio

Inactivation of a Mismatch-Repair System Diversifies Genotypic Landscape of Escherichia coli During Adaptive Laboratory Evolution

(2019) Minjeong Kang et al.   Frontiers in Microbiology

The Aspergillus fumigatus Mismatch Repair MSH2 Homolog Is Important for Virulence and Azole Resistance

(2019) Thaila Fernanda dos Reis et al.   mSphere

A spontaneous mutation in DNA polymerase POL3 during in vitro passaging causes a hypermutator phenotype in Cryptococcus species

(2019) Kylie J. Boyce et al.   DNA REPAIR

Limited DNA repair gene repertoire in Ascomycete yeast revealed by comparative genomics

(2019) Shira Milo et al.   Genome Biology and Evolution

Absence of Azole or Echinocandin Resistance in Candida glabrata Isolates in India despite Background Prevalence of Strains with Defects in the DNA Mismatch Repair Pathway

(2018) Ashutosh Singh et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Profiling of PDR1 and MSH2 in Candida glabrata Bloodstream Isolates from a Multicenter Study in China

(2018) Xin Hou et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Multilocus Sequence Typing (MLST) Genotypes of Candida glabrata Bloodstream Isolates in Korea: Association With Antifungal Resistance, Mutations in Mismatch Repair Gene (Msh2), and Clinical Outcomes

(2018) Seung A. Byun et al.   Frontiers in Microbiology

MSH2 Gene Point Mutations Are Not Antifungal Resistance Markers in Candida glabrata

(2018) María Ángeles Bordallo-Cardona et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Incompatibilities in Mismatch Repair Genes MLH1-PMS1 Contribute to a Wide Range of Mutation Rates in Human Isolates of Baker’s Yeast

(2018) Vandana Raghavan et al.   GENETICS

Hypermutation-induced in vivo oxidative stress resistance enhances Vibrio cholerae host adaptation

(2018) Hui Wang et al.   PLoS Pathogens

Whole Genome Sequencing of Australian Candida glabrata Isolates Reveals Genetic Diversity and Novel Sequence Types

(2018) Chayanika Biswas et al.   Frontiers in Microbiology

Mismatch Repair Incompatibilities in Diverse Yeast Populations

(2017) Duyen T. Bui et al.   GENETICS

Mismatch Repair of DNA Replication Errors Contributes to Microevolution in the Pathogenic Fungus Cryptococcus neoformans

(2017) Kylie J. Boyce et al.   mBio

A Mobile Element in mutS Drives Hypermutation in a Marine Vibrio

(2017) Nathaniel D. Chu et al.   mBio

A Population Genomics Approach to Assessing the Genetic Basis of Within-Host Microevolution Underlying Recurrent Cryptococcal Meningitis Infection

(2017) Johanna Rhodes et al.   G3-Genes Genomes Genetics

Natural mismatch repair mutations mediate phenotypic diversity and drug resistance in Cryptococcus deuterogattii

(2017) R Blake Billmyre et al.   eLife

Mismatch Repair Incompatibilities in Diverse Yeast Populations

(2017) Duyen T. Bui et al.   GENETICS

Tempo and mode of genome evolution in a 50,000-generation experiment

(2016) Olivier Tenaillon et al.   NATURE

Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance

(2016) Kelley R. Healey et al.   Nature Communications

Fluconazole and Echinocandin Resistance of Candida glabrata Correlates Better with Antifungal Drug Exposure Rather than with MSH2 Mutator Genotype in a French Cohort of Patients Harboring Low Rates of Resistance

(2016) Sarah Dellière et al.   Frontiers in Microbiology

Emergence of host-adapted Salmonella Enteritidis through rapid evolution in an immunocompromised host

(2016) Elizabeth J. Klemm et al.   Nature Microbiology

Evidence of a Mild Mutator Phenotype in Cambodian Plasmodium falciparum Malaria Parasites

(2016) Andrew H. Lee et al.   PLoS One

A Genetic Incompatibility Accelerates Adaptation in Yeast

(2015) Duyen T. Bui et al.   PLoS Genetics

Hypermutation in Burkholderia cepacia complex is mediated by DNA mismatch repair inactivation and is highly prevalent in cystic fibrosis chronic respiratory infection

(2014) Pablo Martina et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Mutational landscape of yeast mutator strains

(2014) Alexandre Serero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly Recombinant VGII Cryptococcus gattii Population Develops Clonal Outbreak Clusters through both Sexual Macroevolution and Asexual Microevolution

(2014) R. B. Billmyre et al.   mBio

DNA Repair Mechanisms and the Bypass of DNA Damage in Saccharomyces cerevisiae

(2013) S. Boiteux et al.   GENETICS

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

(2013) Olivo Miotto et al.   NATURE GENETICS

Evaluating evolutionary models of stress-induced mutagenesis in bacteria

(2013) R. Craig MacLean et al.   NATURE REVIEWS GENETICS

β-lactam antibiotics promote bacterial mutagenesis via an RpoS-mediated reduction in replication fidelity

(2013) A. Gutierrez et al.   Nature Communications

Mutation Rates, Spectra, and Genome-Wide Distribution of Spontaneous Mutations in Mismatch Repair Deficient Yeast

(2013) Gregory I. Lang et al.   G3-Genes Genomes Genetics

DNA Mutations Mediate Microevolution between Host-Adapted Forms of the Pathogenic Fungus Cryptococcus neoformans

(2012) Denise A. Magditch et al.   PLoS Pathogens

Balancing eukaryotic replication asymmetry with replication fidelity

(2011) Thomas A Kunkel   CURRENT OPINION IN CHEMICAL BIOLOGY

Malaria drug resistance is associated with defective DNA mismatch repair

(2011) Meryl A. Castellini et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Evolution and Adaptation in Pseudomonas aeruginosa Biofilms Driven by Mismatch Repair System-Deficient Mutators

(2011) Adela M. Luján et al.   PLoS One

Ste20-related kinases: effectors of signaling and morphogenesis in fungi

(2011) Kylie J. Boyce et al.   TRENDS IN MICROBIOLOGY

Correction: Mutator Suppression and Escape from Replication Error–Induced Extinction in Yeast

(2011) Alan J. Herr et al.   PLoS Genetics

Recombination and DNA Repair inHelicobacter pylori

(2010) Marion S. Dorer et al.   Annual Review of Microbiology

Polymorphic Mutation Frequencies of Clinical and Environmental Stenotrophomonas maltophilia Populations

(2010) M. C. Turrientes et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Bacterial hypermutation in cystic fibrosis, not only for antibiotic resistance

(2010) A. Oliver et al.   CLINICAL MICROBIOLOGY AND INFECTION

Mucoidy, Quorum Sensing, Mismatch Repair and Antibiotic Resistance in Pseudomonas aeruginosa from Cystic Fibrosis Chronic Airways Infections

(2010) Sofía Feliziani et al.   PLoS One

Inactivation of mismatch repair increases the diversity ofVibrio parahaemolyticus

(2009) Tracy H. Hazen et al.   ENVIRONMENTAL MICROBIOLOGY

Dynamics of Adaptive Microevolution of HypermutablePseudomonas aeruginosaduring Chronic Pulmonary Infection in Patients with Cystic Fibrosis

(2009) Christina Hoboth et al.   JOURNAL OF INFECTIOUS DISEASES

Effect of mutatorP. aeruginosaon antibiotic resistance acquisition and respiratory function in cystic fibrosis

(2009) Agnes Ferroni et al.   PEDIATRIC PULMONOLOGY

ChronicPseudomonas aeruginosaInfection in Chronic Obstructive Pulmonary Disease

(2008) Laura Martínez‐Solano et al.   CLINICAL INFECTIOUS DISEASES

Phage-Associated Mutator Phenotype in Group A Streptococcus

(2008) J. Scott et al.   JOURNAL OF BACTERIOLOGY

Analysis of base excision and nucleotide excision repair in Candida albicans

(2008) M. Legrand et al.   MICROBIOLOGY-SGM