5-fluorocytosine resistance is associated with hypermutation and alterations in capsule biosynthesis in Cryptococcus

Extensive loss of cell-cycle and DNA repair genes in an ancient lineage of bipolar budding yeasts

(2019) Jacob L. Steenwyk et al.   PLOS BIOLOGY

A Novel Role of Fungal Type I Myosin in Regulating Membrane Properties and Its Association with D-Amino Acid Utilization in Cryptococcus gattii

(2019) Ami Khanal Lamichhane et al.   mBio

Mechanistic Basis of pH-Dependent 5-Flucytosine Resistance in Aspergillus fumigatus

(2018) Fabio Gsaller et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Absence of Azole or Echinocandin Resistance in Candida glabrata Isolates in India despite Background Prevalence of Strains with Defects in the DNA Mismatch Repair Pathway

(2018) Ashutosh Singh et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa

(2018) Síle F. Molloy et al.   NEW ENGLAND JOURNAL OF MEDICINE

RNAi is a critical determinant of centromere evolution in closely related fungi

(2018) Vikas Yadav et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Xylose donor transport is critical for fungal virulence

(2018) Lucy X. Li et al.   PLoS Pathogens

CNBP Homologues Gis2 and Znf9 Interact with a Putative G-Quadruplex-Forming 3′ Untranslated Region, Altering Polysome Association and Stress Tolerance in Cryptococcus neoformans

(2018) Jay Leipheimer et al.   mSphere

Tracing Genetic Exchange and Biogeography of Cryptococcus neoformans var. grubii at the Global Population Level

(2017) Johanna Rhodes et al.   GENETICS

Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis

(2017) Radha Rajasingham et al.   LANCET INFECTIOUS DISEASES

Mismatch Repair of DNA Replication Errors Contributes to Microevolution in the Pathogenic Fungus Cryptococcus neoformans

(2017) Kylie J. Boyce et al.   mBio

A Population Genomics Approach to Assessing the Genetic Basis of Within-Host Microevolution Underlying Recurrent Cryptococcal Meningitis Infection

(2017) Johanna Rhodes et al.   G3-Genes Genomes Genetics

Natural mismatch repair mutations mediate phenotypic diversity and drug resistance in Cryptococcus deuterogattii

(2017) R Blake Billmyre et al.   eLife

Tracing Genetic Exchange and Biogeography of Cryptococcus neoformans var. grubii at the Global Population Level

(2017) Johanna Rhodes et al.   GENETICS

The Case for Adopting the “Species Complex” Nomenclature for the Etiologic Agents of Cryptococcosis

(2017) Kyung J. Kwon-Chung et al.   mSphere

Computational Analysis Reveals a Key Regulator of Cryptococcal Virulence and Determinant of Host Response

(2016) Stacey R. Gish et al.   mBio

Gene Function Analysis in the Ubiquitous Human Commensal and Pathogen Malassezia Genus

(2016) Giuseppe Ianiri et al.   mBio

Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance

(2016) Kelley R. Healey et al.   Nature Communications

Genetic Drivers of Multidrug Resistance in Candida glabrata

(2016) Kelley R. Healey et al.   Frontiers in Microbiology

Fluconazole and Echinocandin Resistance of Candida glabrata Correlates Better with Antifungal Drug Exposure Rather than with MSH2 Mutator Genotype in a French Cohort of Patients Harboring Low Rates of Resistance

(2016) Sarah Dellière et al.   Frontiers in Microbiology

Recognition of seven species in the Cryptococcus gattii/Cryptococcus neoformans species complex

(2015) Ferry Hagen et al.   FUNGAL GENETICS AND BIOLOGY

Genome Evolution and Innovation across the Four Major Lineages of Cryptococcus gattii

(2015) Rhys A. Farrer et al.   mBio

Highly Recombinant VGII Cryptococcus gattii Population Develops Clonal Outbreak Clusters through both Sexual Macroevolution and Asexual Microevolution

(2014) R. B. Billmyre et al.   mBio

Flucytosine and cryptococcosis: time to urgently address the worldwide accessibility of a 50-year-old antifungal

(2013) A. Loyse et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

The variant call format and VCFtools

(2011) P. Danecek et al.   BIOINFORMATICS

FungiDB: an integrated functional genomics database for fungi

(2011) J. E. Stajich et al.   NUCLEIC ACIDS RESEARCH

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

A Ser29Leu Substitution in the Cytosine Deaminase Fca1p Is Responsible for Clade-Specific Flucytosine Resistance in Candida dubliniensis

(2009) B. A. McManus et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Nonsense and Missense Mutations in FCY2 and FCY1 Genes Are Responsible for Flucytosine Resistance and Flucytosine-Fluconazole Cross-Resistance in Clinical Isolates of Candida lusitaniae

(2009) M. Florent et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Cryptococcal Xylosyltransferase 1 (Cxt1p) fromCryptococcus neoformansPlays a Direct Role in the Synthesis of Capsule Polysaccharides

(2008) J. Stacey Klutts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY