Divergent Evolution of Mutation Rates and Biases in the Long-Term Evolution Experiment with Escherichia coli

Low mutational load and high mutation rate variation in gut commensal bacteria

(2020) Ricardo S. Ramiro et al.   PLOS BIOLOGY

Genomic and phenotypic evolution of Escherichia coli in a novel citrate-only resource environment

(2020) Zachary David Blount et al.   eLife

The Symmetrical Wave Pattern of Base-Pair Substitution Rates across the Escherichia coli Chromosome Has Multiple Causes

(2019) Brittany A. Niccum et al.   mBio

High-resolution lineage tracking reveals travelling wave of adaptation in laboratory yeast

(2019) Alex N. Nguyen Ba et al.   NATURE

Innovation in an E. coli evolution experiment is contingent on maintaining adaptive potential until competition subsides

(2018) Dacia Leon et al.   PLoS Genetics

High mutation rates limit evolutionary adaptation in Escherichia coli

(2018) Kathleen Sprouffske et al.   PLoS Genetics

Directed evolution of Escherichia coli with lower-than-natural plasmid mutation rates

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Periodic Variation of Mutation Rates in Bacterial Genomes Associated with Replication Timing

(2018) Marcus M. Dillon et al.   mBio

Core Genes Evolve Rapidly in the Long-Term Evolution Experiment with Escherichia coli

(2017) Rohan Maddamsetti et al.   Genome Biology and Evolution

The dynamics of molecular evolution over 60,000 generations

(2017) Benjamin H. Good et al.   NATURE

Mutator genomes decay, despite sustained fitness gains, in a long-term experiment with bacteria

(2017) Alejandro Couce et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sexual recombination and increased mutation rate expedite evolution of Escherichia coli in varied fitness landscapes

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Benefits of a Recombination-Proficient Escherichia coli System for Adaptive Laboratory Evolution

(2016) George Peabody et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Rates and mechanisms of bacterial mutagenesis from maximum-depth sequencing

(2016) Justin Jee et al.   NATURE

Tempo and mode of genome evolution in a 50,000-generation experiment

(2016) Olivier Tenaillon et al.   NATURE

Genetic drift, selection and the evolution of the mutation rate

(2016) Michael Lynch et al.   NATURE REVIEWS GENETICS

Adaptation, Clonal Interference, and Frequency-Dependent Interactions in a Long-Term Evolution Experiment with Escherichia coli

(2015) Rohan Maddamsetti et al.   GENETICS

Synonymous Genetic Variation in Natural Isolates ofEscherichia coliDoes Not Predict Where Synonymous Substitutions Occur in a Long-Term Experiment

(2015) Rohan Maddamsetti et al.   MOLECULAR BIOLOGY AND EVOLUTION

Asymmetric Context-Dependent Mutation Patterns Revealed through Mutation–Accumulation Experiments

(2015) Way Sung et al.   MOLECULAR BIOLOGY AND EVOLUTION

Quantitative evolutionary dynamics using high-resolution lineage tracking

(2015) Sasha F. Levy et al.   NATURE

Determinants of spontaneous mutation in the bacteriumEscherichia colias revealed by whole-genome sequencing

(2015) Patricia L. Foster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptation, Clonal Interference, and Frequency-Dependent Interactions in a Long-Term Evolution Experiment with Escherichia coli

(2015) Rohan Maddamsetti et al.   GENETICS

Genetic Draft, Selective Interference, and Population Genetics of Rapid Adaptation

(2013) Richard A. Neher   Annual Review of Ecology Evolution and Systematics

No Gene-Specific Optimization of Mutation Rate in Escherichia coli

(2013) X. Chen et al.   MOLECULAR BIOLOGY AND EVOLUTION

Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populations

(2013) Gregory I. Lang et al.   NATURE

Accelerated gene evolution through replication–transcription conflicts

(2013) Sandip Paul et al.   NATURE

On the Mutational Topology of the Bacterial Genome

(2013) Patricia L. Foster et al.   G3-Genes Genomes Genetics

Genomic analysis of a key innovation in an experimental Escherichia coli population

(2012) Zachary D. Blount et al.   NATURE

Evidence of non-random mutation rates suggests an evolutionary risk management strategy

(2012) Iñigo Martincorena et al.   NATURE

Rate and molecular spectrum of spontaneous mutations in the bacterium Escherichia coli as determined by whole-genome sequencing

(2012) H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutation rate dynamics in a bacterial population reflect tension between adaptation and genetic load

(2012) S. Wielgoss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emergent Neutrality in Adaptive Asexual Evolution

(2011) Stephan Schiffels et al.   GENETICS

Mutation Rates across Budding Yeast Chromosome VI Are Correlated with Replication Timing

(2011) Gregory I. Lang et al.   Genome Biology and Evolution

Parallel Genetic and Phenotypic Evolution of DNA Superhelicity in Experimental Populations of Escherichia coli

(2010) E. Crozat et al.   MOLECULAR BIOLOGY AND EVOLUTION

Optimization of DNA polymerase mutation rates during bacterial evolution

(2009) E. Loh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GC skew in protein-coding genes between the leading and lagging strands in bacterial genomes: New substitution models incorporating strand bias

(2008) Antonio Marín et al.   JOURNAL OF THEORETICAL BIOLOGY