Host Cell Oxidative Stress Induces Dormant Staphylococcus aureus Persisters

Molecular reprogramming and phenotype switching in Staphylococcus aureus lead to high antibiotic persistence and affect therapy success

(2021) Markus Huemer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Aggregation as a Bacterial Strategy to Survive Antibiotic Treatment

(2021) Celien Bollen et al.   Frontiers in Molecular Biosciences

The classification of bacterial survival strategies in the presence of antimicrobials

(2021) Igor V. Chebotar’ et al.   MICROBIAL PATHOGENESIS

The Dynamic Transition of Persistence toward the Viable but Nonculturable State during Stationary Phase Is Driven by Protein Aggregation

(2021) Liselot Dewachter et al.   mBio

Intracellular Staphylococcus aureus persisters upon antibiotic exposure

(2020) Frédéric Peyrusson et al.   Nature Communications

The alarmones (p)ppGpp directly regulate translation initiation during entry into quiescence

(2020) Simon Diez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The protein translation machinery is expressed for maximal efficiency in Escherichia coli

(2020) Xiao-Pan Hu et al.   Nature Communications

The Persister Character of Clinical Isolates of Staphylococcus aureus Contributes to Faster Evolution to Resistance and Higher Survival in THP-1 Monocytes: A Study With Moxifloxacin

(2020) Tiep K. Nguyen et al.   Frontiers in Microbiology

Impact of bacterial persisters on their host

(2020) Ana L Moldoveanu et al.   CURRENT OPINION IN MICROBIOLOGY

Bacterial persistence promotes the evolution of antibiotic resistance by increasing survival and mutation rates

(2019) Etthel Martha Windels et al.   ISME Journal

The Role of the Host in Driving Phenotypic Heterogeneity in Salmonella

(2019) Caressa N. Tsai et al.   TRENDS IN MICROBIOLOGY

Definitions and guidelines for research on antibiotic persistence

(2019) Nathalie Q. Balaban et al.   NATURE REVIEWS MICROBIOLOGY

(p)ppGpp and the Stringent Response: An Emerging Threat to Antibiotic Therapy

(2019) Joanne K. Hobbs et al.   ACS Infectious Diseases

Protein aggregation in bacteria

(2019) Frederic D Schramm et al.   FEMS MICROBIOLOGY REVIEWS

Bacterial ageing in the absence of external stressors

(2019) Urszula Łapińska et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Reactive oxygen species induce antibiotic tolerance during systemic Staphylococcus aureus infection

(2019) Sarah E. Rowe et al.   Nature Microbiology

Single cell observations show persister cells wake based on ribosome content

(2018) Jun-Seob Kim et al.   ENVIRONMENTAL MICROBIOLOGY

Viable but non-culturable and persistence describe the same bacterial stress state

(2018) Jun-Seob Kim et al.   ENVIRONMENTAL MICROBIOLOGY

Relationship between the Viable but Nonculturable State and Antibiotic Persister Cells

(2018) Mesrop Ayrapetyan et al.   JOURNAL OF BACTERIOLOGY

Inactivation of TCA cycle enhances Staphylococcus aureus persister cell formation in stationary phase

(2018) Ying Wang et al.   Scientific Reports

Protein aggregates encode epigenetic memory of stressful encounters in individual Escherichia coli cells

(2018) Sander K. Govers et al.   PLOS BIOLOGY

ATP-Dependent Dynamic Protein Aggregation Regulates Bacterial Dormancy Depth Critical for Antibiotic Tolerance

(2018) Yingying Pu et al.   MOLECULAR CELL

Persistent bacterial infections and persister cells

(2017) Robert A. Fisher et al.   NATURE REVIEWS MICROBIOLOGY

ATP as a biological hydrotrope

(2017) Avinash Patel et al.   SCIENCE

Antibiotic tolerance facilitates the evolution of resistance

(2017) Irit Levin-Reisman et al.   SCIENCE

A Numbers Game: Ribosome Densities, Bacterial Growth, and Antibiotic-Mediated Stasis and Death

(2017) Bruce R. Levin et al.   mBio

Distinguishing between resistance, tolerance and persistence to antibiotic treatment

(2016) Asher Brauner et al.   NATURE REVIEWS MICROBIOLOGY

Mechanisms of bacterial persistence during stress and antibiotic exposure

(2016) Alexander Harms et al.   SCIENCE

Persister formation in Staphylococcus aureus is associated with ATP depletion

(2016) Brian P. Conlon et al.   Nature Microbiology

Development of Persister-FACSeq: a method to massively parallelize quantification of persister physiology and its heterogeneity

(2016) Theresa C. Henry et al.   Scientific Reports

Intracellular replication ofStaphylococcus aureusin mature phagolysosomes in macrophages precedes host cell death, and bacterial escape and dissemination

(2015) Ronald S. Flannagan et al.   CELLULAR MICROBIOLOGY

Microbial bet-hedging: the power of being different

(2015) Ard Jan Grimbergen et al.   CURRENT OPINION IN MICROBIOLOGY

Repairing oxidized proteins in the bacterial envelope using respiratory chain electrons

(2015) Alexandra Gennaris et al.   NATURE

Bridging the gap between viable but non-culturable and antibiotic persistent bacteria

(2015) Mesrop Ayrapetyan et al.   TRENDS IN MICROBIOLOGY

Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations

(2014) Ofer Fridman et al.   NATURE

Internalization of Salmonella by Macrophages Induces Formation of Nonreplicating Persisters

(2014) S. Helaine et al.   SCIENCE

The importance of the viable but non-culturable state in human bacterial pathogens

(2014) Laam Li et al.   Frontiers in Microbiology

Dormancy Is Not Necessary or Sufficient for Bacterial Persistence

(2013) Mehmet A. Orman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Activated ClpP kills persisters and eradicates a chronic biofilm infection

(2013) B. P. Conlon et al.   NATURE

Unraveling the Mechanism of Protein Disaggregation Through a ClpB-DnaK Interaction

(2013) R. Rosenzweig et al.   SCIENCE

The task force that rescues stalled ribosomes in bacteria

(2013) Emmanuel Giudice et al.   TRENDS IN BIOCHEMICAL SCIENCES

An insight into the significance of the DnaK heat shock system in Staphylococcus aureus

(2012) Vineet K. Singh et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Signaling-mediated bacterial persister formation

(2012) Nicole M Vega et al.   Nature Chemical Biology

Staphylococcal response to oxidative stress

(2012) Rosmarie Gaupp et al.   Frontiers in Cellular and Infection Microbiology

Drug Tolerance in Replicating Mycobacteria Mediated by a Macrophage-Induced Efflux Mechanism

(2011) Kristin N. Adams et al.   CELL

A novel flow cytometry-based assay for the quantification of Staphylococcus aureus adhesion to and invasion of eukaryotic cells

(2011) Sophie Trouillet et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Metabolite-enabled eradication of bacterial persisters by aminoglycosides

(2011) Kyle R. Allison et al.   NATURE

Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE

The Frequency of Persisters in Escherichia coli Reflects the Kinetics of Awakening from Dormancy

(2010) A. Joers et al.   JOURNAL OF BACTERIOLOGY

Dynamics of intracellular bacterial replication at the single cell level

(2010) Sophie Helaine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Energy production genessucBandubiF  are involved in persister survival and tolerance to multiple antibiotics and stresses inEscherichia coli

(2009) Chao Ma et al.   FEMS MICROBIOLOGY LETTERS

Cell division in Escherichia coli cultures monitored at single cell resolution

(2008) Johanna Roostalu et al.   BMC MICROBIOLOGY

A Potential New Pathway for Staphylococcus aureus Dissemination: The Silent Survival of S. aureus Phagocytosed by Human Monocyte-Derived Macrophages

(2008) Malgorzata Kubica et al.   PLoS One

Asymmetric segregation of protein aggregates is associated with cellular aging and rejuvenation

(2008) A. B. Lindner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA