Protein aggregates encode epigenetic memory of stressful encounters in individual Escherichia coli cells

Cellular Handling of Protein Aggregates by Disaggregation Machines

(2018) Axel Mogk et al.   MOLECULAR CELL

Mechanically switching single-molecule fluorescence of GFP by unfolding and refolding

(2017) Ziad Ganim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A bacterial global regulator forms a prion

(2017) Andy H. Yuan et al.   SCIENCE

Rapid phenotypic individualization of bacterial sister cells

(2017) Sander K. Govers et al.   Scientific Reports

Aging, mortality, and the fast growth trade-off of Schizosaccharomyces pombe

(2017) Hidenori Nakaoka et al.   PLOS BIOLOGY

Visualization of Periplasmic and Cytoplasmic Proteins with a Self-Labeling Protein Tag

(2016) Na Ke et al.   JOURNAL OF BACTERIOLOGY

In vivo aspects of protein folding and quality control

(2016) D. Balchin et al.   SCIENCE

Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular protection and efficient refolding

(2016) Sophia Ungelenk et al.   Nature Communications

A pH-driven transition of the cytoplasm from a fluid- to a solid-like state promotes entry into dormancy

(2016) Matthias Christoph Munder et al.   eLife

Reversible, Specific, Active Aggregates of Endogenous Proteins Assemble upon Heat Stress

(2015) Edward W.J. Wallace et al.   CELL

Widespread Proteome Remodeling and Aggregation in Aging C. elegans

(2015) Dirk M. Walther et al.   CELL

Oufti: an integrated software package for high-accuracy, high-throughput quantitative microscopy analysis

(2015) Ahmad Paintdakhi et al.   MOLECULAR MICROBIOLOGY

Increased cytoplasm viscosity hampers aggregate polar segregation inEscherichia coli

(2015) Samuel M. D. Oliveira et al.   MOLECULAR MICROBIOLOGY

Proteostasis and aging

(2015) Susmita Kaushik et al.   NATURE MEDICINE

Protein aggregates are associated with replicative aging without compromising protein quality control

(2015) Juha Saarikangas et al.   eLife

In Vivo Disassembly and Reassembly of Protein Aggregates in Escherichia coli

(2014) S. K. Govers et al.   JOURNAL OF BACTERIOLOGY

Challenges and dreams: physics of weak interactions essential to life

(2014) Peter Chien et al.   MOLECULAR BIOLOGY OF THE CELL

Sequential evolution of bacterial morphology by co-option of a developmental regulator

(2014) Chao Jiang et al.   NATURE

Energy landscapes of functional proteins are inherently risky

(2014) Anne Gershenson et al.   Nature Chemical Biology

Fusion of Protein Aggregates Facilitates Asymmetric Damage Segregation

(2014) Miguel Coelho et al.   PLOS BIOLOGY

Dynamic transcriptional response ofEscherichia colito inclusion body formation

(2013) Faraz Baig et al.   BIOTECHNOLOGY AND BIOENGINEERING

A Super-Assembly of Whi3 Encodes Memory of Deceptive Encounters by Single Cells during Yeast Courtship

(2013) Fabrice Caudron et al.   CELL

Four-Dimensional Imaging of E. coli Nucleoid Organization and Dynamics in Living Cells

(2013) Jay K. Fisher et al.   CELL

Protein rescue from aggregates by powerful molecular chaperone machines

(2013) Shannon M. Doyle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Localization of Protein Aggregation in Escherichia coli Is Governed by Diffusion and Nucleoid Macromolecular Crowding Effect

(2013) Anne-Sophie Coquel et al.   PLoS Computational Biology

Fusion protein linkers: Property, design and functionality

(2012) Xiaoying Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

The Helical MreB Cytoskeleton in Escherichia coli MC1000/pLE7 Is an Artifact of the N-Terminal Yellow Fluorescent Protein Tag

(2012) Matthew T. Swulius et al.   JOURNAL OF BACTERIOLOGY

Protein Aggregation Caused by Aminoglycoside Action Is Prevented by a Hydrogen Peroxide Scavenger

(2012) Jiqiang Ling et al.   MOLECULAR CELL

Segregation of molecules at cell division reveals native protein localization

(2012) Dirk Landgraf et al.   NATURE METHODS

A Yeast Prion, Mod5, Promotes Acquired Drug Resistance and Cell Survival Under Environmental Stress

(2012) G. Suzuki et al.   SCIENCE

Amyloid-like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions

(2011) Heidi Olzscha et al.   CELL

High-throughput, subpixel precision analysis of bacterial morphogenesis and intracellular spatio-temporal dynamics

(2011) Oleksii Sliusarenko et al.   MOLECULAR MICROBIOLOGY

Quantitative and spatio-temporal features of protein aggregation in Escherichia coli and consequences on protein quality control and cellular ageing

(2010) Juliane Winkler et al.   EMBO JOURNAL

Pre-dispositions and epigenetic inheritance in the Escherichia coli lactose operon bistable switch

(2010) Lydia Robert et al.   Molecular Systems Biology

Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast

(2010) K. A. Geiler-Samerotte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quaternary dynamics and plasticity underlie small heat shock protein chaperone function

(2010) F. Stengel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Model for Damage Load and Its Implications for the Evolution of Bacterial Aging

(2010) Lin Chao   PLoS Genetics

The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7,in vitro

(2009) Christian Johannes Gloeckner et al.   JOURNAL OF NEUROCHEMISTRY

Widespread reorganization of metabolic enzymes into reversible assemblies upon nutrient starvation

(2009) R. Narayanaswamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bistability, Epigenetics, and Bet-Hedging in Bacteria

(2008) Jan-Willem Veening et al.   Annual Review of Microbiology

Protein Aggregates: an Aging Factor Involved in Cell Death

(2008) E. Maisonneuve et al.   JOURNAL OF BACTERIOLOGY

Distinct Activities of Escherichia coli Small Heat Shock Proteins IbpA and IbpB Promote Efficient Protein Disaggregation

(2008) Elżbieta Ratajczak et al.   JOURNAL OF MOLECULAR BIOLOGY

Convergence of Molecular, Modeling, and Systems Approaches for an Understanding of the Escherichia coli Heat Shock Response

(2008) E. Guisbert et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

DNA dynamics vary according to macrodomain topography in theE. colichromosome

(2008) Olivier Espeli et al.   MOLECULAR MICROBIOLOGY

Selective benefits of damage partitioning in unicellular systems and its effects on aging

(2008) N. Erjavec et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Asymmetric segregation of protein aggregates is associated with cellular aging and rejuvenation

(2008) A. B. Lindner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hsp104 and ClpB: protein disaggregating machines

(2008) Shannon M. Doyle et al.   TRENDS IN BIOCHEMICAL SCIENCES