Notoginsenoside R1 Protects Against High Glucose-Induced Cell Injury Through AMPK/Nrf2 and Downstream HO-1 Signaling

Prediabetes and the risk of heart failure: A meta‐analysis

(2021) Xiaoyan Cai et al.   DIABETES OBESITY & METABOLISM

Association between prediabetes and adverse outcomes in heart failure

(2021) Linlin Mai et al.   DIABETES OBESITY & METABOLISM

Diabetes in Patients With Heart Failure With Reduced Ejection Fraction During Hospitalization: A Retrospective Observational Study

(2021) Yiling Zhou et al.   Frontiers in Endocrinology

SFRP2 Improves Mitochondrial Dynamics and Mitochondrial Biogenesis, Oxidative Stress, and Apoptosis in Diabetic Cardiomyopathy

(2021) Tianyi Ma et al.   Oxidative Medicine and Cellular Longevity

Mitophagy in Diabetic Cardiomyopathy: Roles and Mechanisms

(2021) Haoxiao Zheng et al.   Frontiers in Cell and Developmental Biology

Role of Sfrps in cardiovascular disease

(2020) Anqing Huang et al.   Therapeutic Advances in Chronic Disease

Strawberry Leaf Extract Treatment Alleviates Cognitive Impairment by Activating Nrf2/HO-1 Signaling in Rats With Streptozotocin-Induced Diabetes

(2020) Li Zhang et al.   Frontiers in Aging Neuroscience

Prognostic Value of Secreted Frizzled-Related Protein 5 in Heart Failure Patients With and Without Type 2 Diabetes Mellitus

(2020) Jiandi Wu et al.   Circulation-Heart Failure

Notoginsenoside R1 Protects db/db Mice against Diabetic Nephropathy via Upregulation of Nrf2-Mediated HO-1 Expression

(2019) Bin Zhang et al.   MOLECULES

Diabetic Cardiomyopathy

(2018) Guanghong Jia et al.   CIRCULATION RESEARCH

Raf kinase inhibitor protein mediates myocardial fibrosis under conditions of enhanced myocardial oxidative stress

(2018) Andrey Kazakov et al.   BASIC RESEARCH IN CARDIOLOGY

Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling

(2018) Bin Zhang et al.   Frontiers in Pharmacology

Wogonin, a plant derived small molecule, exerts potent anti-inflammatory and chondroprotective effects through the activation of ROS/ERK/Nrf2 signaling pathways in human Osteoarthritis chondrocytes

(2017) Nazir M. Khan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ginsenoside Rb1 exerts antidiabetic action on C2C12 muscle cells by leptin receptor signaling pathway

(2017) Mohammad Reza Tabandeh et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Myricetin Possesses Potential Protective Effects on Diabetic Cardiomyopathy through Inhibiting IκBα/NFκB and Enhancing Nrf2/HO-1

(2017) Hai-han Liao et al.   Oxidative Medicine and Cellular Longevity

Methylglyoxal-Induced Endothelial Cell Loss and Inflammation Contribute to the Development of Diabetic Cardiomyopathy

(2016) Branka Vulesevic et al.   DIABETES

Notoginsenoside R1 ameliorates podocyte injury in rats with diabetic nephropathy by activating the PI3K/Akt signaling pathway

(2016) Guodong Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

AMPK Facilitates Nuclear Accumulation of Nrf2 by Phosphorylating at Serine 550

(2016) Min Sung Joo et al.   MOLECULAR AND CELLULAR BIOLOGY

Cardioprotective Effect of Ulmus wallichiana Planchon in β-Adrenergic Agonist Induced Cardiac Hypertrophy

(2016) Anees A. Syed et al.   Frontiers in Pharmacology

Cardioprotective effects of Notoginsenoside R1 against ischemia/reperfusion injuries by regulating oxidative stress- and endoplasmic reticulum stress- related signaling pathways

(2016) Yingli Yu et al.   Scientific Reports

The protective effects of endogenous hydrogen sulfide modulator, S-propargyl-cysteine, on high glucose-induced apoptosis in cardiomyocytes: A novel mechanism mediated by the activation of Nrf2

(2015) Hebei Yang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Activated AMPK boosts the Nrf2/HO-1 signaling axis—A role for the unfolded protein response

(2015) Kristin Zimmermann et al.   FREE RADICAL BIOLOGY AND MEDICINE

Suppression of NADPH oxidase- and mitochondrion-derived superoxide by Notoginsenoside R1 protects against cerebral ischemia–reperfusion injury through estrogen receptor-dependent activation of Akt/Nrf2 pathways

(2014) X. Meng et al.   FREE RADICAL RESEARCH

Nrf2 enhances myocardial clearance of toxic ubiquitinated proteins

(2014) Wenjuan Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

KEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants

(2013) Bibo Ke et al.   JOURNAL OF HEPATOLOGY

Adrenergic signaling and oxidative stress: a role for sirtuins?

(2013) Graziamaria Corbi et al.   Frontiers in Physiology

Notoginsenoside R1 attenuates cardiac dysfunction in endotoxemic mice: an insight into oestrogen receptor activation and PI3K/Akt signalling

(2012) Bing Sun et al.   BRITISH JOURNAL OF PHARMACOLOGY

Induction of Heme Oxygenase-1 Inhibits Cell Death in Crotonaldehyde-Stimulated HepG2 Cells via the PKC-δ -p38 -Nrf2 Pathway

(2012) Seung Eun Lee et al.   PLoS One

The protective effect of magnesium lithospermate B against glucose-induced intracellular oxidative damage

(2011) Jian Qu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hyperglycaemia-induced cardiomyocyte death is mediated via MCP-1 production and induction of a novel zinc-finger protein MCPIP

(2010) Craig W. Younce et al.   CARDIOVASCULAR RESEARCH

Deficiency in AMP-activated protein kinase exaggerates high fat diet-induced cardiac hypertrophy and contractile dysfunction

(2010) Subat Turdi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Transcriptional Regulation of Renal Cytoprotective Genes by Nrf2 and Its Potential Use as a Therapeutic Target to Mitigate Cisplatin-Induced Nephrotoxicity

(2010) L. M. Aleksunes et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Ginsenoside Rb1 Preconditioning Protects Against Myocardial Infarction After Regional Ischemia and Reperfusion by Activation of Phosphatidylinositol-3-kinase Signal Transduction

(2008) Zhi Wang et al.   CARDIOVASCULAR DRUGS AND THERAPY