Cardioprotective effects of Notoginsenoside R1 against ischemia/reperfusion injuries by regulating oxidative stress- and endoplasmic reticulum stress- related signaling pathways

Protective Mechanisms of Mitochondria and Heart Function in Diabetes

(2015) Miguel A. Aon et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial JNK activation triggers autophagy and apoptosis and aggravates myocardial injury following ischemia/reperfusion

(2015) Jie Xu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Structural apelin analogues: mitochondrial ROS inhibition and cardiometabolic protection in myocardial ischaemia reperfusion injury

(2015) Oleg Pisarenko et al.   BRITISH JOURNAL OF PHARMACOLOGY

Ischaemic preconditioning preferentially increases protein S-nitrosylation in subsarcolemmal mitochondria

(2015) Junhui Sun et al.   CARDIOVASCULAR RESEARCH

Hypercholesterolemia aggravates myocardial ischemia reperfusion injury via activating endoplasmic reticulum stress-mediated apoptosis

(2015) Nan Wu et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Basic mechanisms in endoplasmic reticulum stress and relation to cardiovascular diseases

(2015) Erdi Sozen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Elatoside C protects the heart from ischaemia/reperfusion injury through the modulation of oxidative stress and intracellular Ca2+ homeostasis

(2015) Min Wang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Nerve Growth Factor Protects the Ischemic Heart via Attenuation of the Endoplasmic Reticulum Stress Induced Apoptosis by Activation of Phosphatidylinositol 3-Kinase

(2015) Ke Wei et al.   International Journal of Medical Sciences

Cordycepin induced MA-10 mouse Leydig tumor cell apoptosis by regulating p38 MAPKs and PI3K/AKT signaling pathways

(2015) Bo-Syong Pan et al.   Scientific Reports

Involvement of normalized NMDA receptor and mTOR-related signaling in rapid antidepressant effects of Yueju and ketamine on chronically stressed mice

(2015) Juanjuan Tang et al.   Scientific Reports

Ganoderma lucidum polysaccharide peptide prevents renal ischemia reperfusion injury via counteracting oxidative stress

(2015) Dandan Zhong et al.   Scientific Reports

Therapeutic window of globular adiponectin against cerebral ischemia in diabetic mice: the role of dynamic alteration of adiponectin/adiponectin receptor expression

(2015) Wenying Song et al.   Scientific Reports

Ischemia/reperfusion injury: Effect of simultaneous inhibition of plasma cascade systems versus specific complement inhibition

(2014) Claudia Duehrkop et al.   BIOCHEMICAL PHARMACOLOGY

The role of MAPK signalling pathways in the response to endoplasmic reticulum stress

(2014) Nicola J. Darling et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Notoginsenoside R1-mediated neuroprotection involves estrogen receptor-dependent crosstalk between Akt and ERK1/2 pathways: A novel mechanism of Nrf2/ARE signaling activation

(2014) X. Meng et al.   FREE RADICAL RESEARCH

Notoginsenoside R1 attenuates amyloid-β-induced damage in neurons by inhibiting reactive oxygen species and modulating MAPK activation

(2014) Bo Ma et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Endoplasmic reticulum stress is accompanied by activation of NF-κB in amyotrophic lateral sclerosis

(2014) T. Prell et al.   JOURNAL OF NEUROIMMUNOLOGY

Down-regulation of GRP78 enhances apoptosis via CHOP pathway in retinal ischemia-reperfusion injury

(2014) Huiling Li et al.   NEUROSCIENCE LETTERS

Antioxidative effects of Panax notoginseng saponins in brain cells

(2014) Ningna Zhou et al.   PHYTOMEDICINE

4-Phenylbutyric acid prevent cytotoxicity induced by thapsigargin in rat cardiac fibroblast

(2014) C. Humeres et al.   TOXICOLOGY IN VITRO

Calumenin has a role in the alleviation of ER stress in neonatal rat cardiomyocytes

(2013) Joo Hee Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

4-Phenylbutyric acid protects against neuronal cell death by primarily acting as a chemical chaperone rather than histone deacetylase inhibitor

(2013) Seisuke Mimori et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Tunicamycin inhibits Toll-like receptor-activated inflammation in RAW264.7 cells by suppression of NF-κB and c-Jun activity via a mechanism that is independent of ER-stress and N-glycosylation

(2013) Song-Yi Kim et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Inhibition of PKR protects against tunicamycin-induced apoptosis in neuroblastoma cells

(2013) Lauren S. Vaughn et al.   GENE

Pinocembrin protects brain against ischemia/reperfusion injury by attenuating endoplasmic reticulum stress induced apoptosis

(2013) Cai-xia Wu et al.   NEUROSCIENCE LETTERS

Pharmacological targeting of endoplasmic reticulum stress signaling in cancer

(2012) Axel H. Schönthal   BIOCHEMICAL PHARMACOLOGY

Endoplasmic reticulum: The unfolded protein response is tangled in neurodegeneration

(2012) Jeroen J.M. Hoozemans et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

bFGF inhibits ER stress induced by ischemic oxidative injury via activation of the PI3K/Akt and ERK1/2 pathways

(2012) Zhouguang Wang et al.   TOXICOLOGY LETTERS

Panax notoginseng and its components decreased hypertension via stimulation of endothelial-dependent vessel dilatation

(2012) Chunshui Pan et al.   VASCULAR PHARMACOLOGY

Calcium entry via TRPC6 mediates albumin overload-induced endoplasmic reticulum stress and apoptosis in podocytes

(2011) Shan Chen et al.   CELL CALCIUM

Endoplasmic reticulum stress-induced CHOP activation mediates the down-regulation of leptin in human neuroblastoma SH-SY5Y cells treated with the oxysterol 27-hydroxycholesterol

(2011) Gurdeep Marwarha et al.   CELLULAR SIGNALLING

The endoplasmic reticulum stress response is involved in apoptosis induced by aloe-emodin in HK-2 cells

(2011) Shaohua Zhu et al.   FOOD AND CHEMICAL TOXICOLOGY

Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics

(2011) Roberto Bravo et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Panax notoginseng saponins inhibit ischemia-induced apoptosis by activating PI3K/Akt pathway in cardiomyocytes

(2011) Shaoxian Chen et al.   JOURNAL OF ETHNOPHARMACOLOGY

ER stress in retinal degeneration: a target for rational therapy?

(2011) Ana Griciuc et al.   TRENDS IN MOLECULAR MEDICINE

Ischemia induces endoplasmic reticulum stress and cell apoptosis in human brain

(2010) Shu-rong Duan et al.   NEUROSCIENCE LETTERS

Increased ROS Production: A Component of the Longevity Equation in the Male Mygalomorph, Brachypelma albopilosa

(2010) Francois Criscuolo et al.   PLoS One

ER stress in cardiovascular disease

(2009) Tetsuo Minamino et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Total saponins of Panax Notoginseng modulate the expression of caspases and attenuate apoptosis in rats following focal cerebral ischemia-reperfusion

(2008) Hua Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

(2008) Inki Kim et al.   NATURE REVIEWS DRUG DISCOVERY