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Title
Targeting Phosphatases and Kinases: How to Checkmate Cancer
Authors
Keywords
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Journal
Frontiers in Cell and Developmental Biology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-10-28
DOI
10.3389/fcell.2021.690306
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Note: Only part of the references are listed.- PI3K-driven HER2 expression is a potential therapeutic target in colorectal cancer stem cells
- (2021) Laura Rosa Mangiapane et al. GUT
- Properties of FDA-approved small molecule protein kinase inhibitors: a 2021 update
- (2021) Robert Roskoski PHARMACOLOGICAL RESEARCH
- Orally effective FDA-approved protein kinase targeted covalent inhibitors (TCIs)
- (2021) Robert Roskoski PHARMACOLOGICAL RESEARCH
- Cancer stem cell phosphatases
- (2021) Majid Momeny et al. BIOCHEMICAL JOURNAL
- Hydrophobic and polar interactions of FDA-approved small molecule protein kinase inhibitors with their target enzymes
- (2021) Robert Roskoski PHARMACOLOGICAL RESEARCH
- Nobiletin and Xanthohumol Sensitize Colorectal Cancer Stem Cells to Standard Chemotherapy
- (2021) Alice Turdo et al. Cancers
- The role of PPM1D in cancer and advances in studies of its inhibitors
- (2020) Wenhong Deng et al. BIOMEDICINE & PHARMACOTHERAPY
- Dual specificity phosphatase 6 plays a critical role in the maintenance of a cancer stem‐like cell phenotype in human endometrial cancer
- (2020) Masaya Kato et al. INTERNATIONAL JOURNAL OF CANCER
- Metabolic Escape Routes of Cancer Stem Cells and Therapeutic Opportunities
- (2020) Alice Turdo et al. Cancers
- Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem Cells
- (2020) Garry L. Coles et al. CANCER CELL
- Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer
- (2020) Priscilla Cheung et al. Cell Stem Cell
- Mislocalisation of Activated Receptor Tyrosine Kinases – Challenges for Cancer Therapy
- (2020) Dirk Schmidt-Arras et al. TRENDS IN MOLECULAR MEDICINE
- PIK3C3 regulates the expansion of liver CSCs and PIK3C3 inhibition counteracts liver cancer stem cell activity induced by PI3K inhibitor
- (2020) Fengchao Liu et al. Cell Death & Disease
- Src Family Kinases as Therapeutic Targets in Advanced Solid Tumors: What We Have Learned So Far
- (2020) Stefano Martellucci et al. Cancers
- Cancer Stem Cells in Thyroid Tumors: From the Origin to Metastasis
- (2020) Veronica Veschi et al. Frontiers in Endocrinology
- B591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cells
- (2019) Hongyu Zhou et al. ONCOGENE
- JAK/STAT3 and NF-κB Signaling Pathways Regulate Cancer Stem-Cell Properties in Anaplastic Thyroid Cancer Cells
- (2019) Ken Shiraiwa et al. THYROID
- Potent Antineoplastic Effects of Combined PI3Kα–MNK Inhibition in Medulloblastoma
- (2019) Frank Eckerdt et al. MOLECULAR CANCER RESEARCH
- IL-10 derived from M2 macrophage promotes cancer stemness via JAK1/STAT1/NF-κB/Notch1 pathway in non-small cell lung cancer
- (2019) Li Yang et al. INTERNATIONAL JOURNAL OF CANCER
- Inhibition of PI3K/Akt/mTOR signaling pathway alleviates ovarian cancer chemoresistance through reversing epithelial-mesenchymal transition and decreasing cancer stem cell marker expression
- (2019) Junli Deng et al. BMC CANCER
- Comment on “PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL human leukemia”
- (2019) Danilo Perrotti et al. Science Translational Medicine
- Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant
- (2019) Veronica Veschi et al. ONCOGENE
- Erlotinib overcomes paclitaxel-resistant cancer stem cells by blocking the EGFR-CREB/GRβ-IL-6 axis in MUC1-positive cervical cancer
- (2019) Yaping Lv et al. Oncogenesis
- Pharmacological inhibition of DUSP6 suppresses gastric cancer growth and metastasis and overcomes cisplatin resistance
- (2018) Qi-Nian Wu et al. CANCER LETTERS
- Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF-1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment
- (2018) Haiquan Lu et al. CANCER RESEARCH
- Quercetin suppresses breast cancer stem cells (CD44 + /CD24 − ) by inhibiting the PI3K/Akt/mTOR-signaling pathway
- (2018) Xiuli Li et al. LIFE SCIENCES
- The functions and regulation of the PTEN tumour suppressor: new modes and prospects
- (2018) Yu-Ru Lee et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The role of small molecule Kit protein-tyrosine kinase inhibitors in the treatment of neoplastic disorders
- (2018) Robert Roskoski PHARMACOLOGICAL RESEARCH
- PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL + human leukemia
- (2018) Damian Lai et al. Science Translational Medicine
- Human colorectal cancer-derived mesenchymal stem cells promote colorectal cancer progression through IL-6/JAK2/STAT3 signaling
- (2018) Xiaochao Zhang et al. Cell Death & Disease
- Keeping Tumors Out of the MAPK Fitness Zone
- (2018) David F. Stern Cancer Discovery
- CDK5 Inhibition Resolves PKA/cAMP-Independent Activation of CREB1 Signaling in Glioma Stem Cells
- (2018) Subhas Mukherjee et al. Cell Reports
- Targeting an oncogenic kinase/phosphatase signaling network for cancer therapy
- (2018) Xiao-Mei Qi et al. Acta Pharmaceutica Sinica B
- Targeting oncogenic Raf protein-serine/threonine kinases in human cancers
- (2018) Robert Roskoski PHARMACOLOGICAL RESEARCH
- Phosphatases start shedding their stigma of undruggability
- (2018) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- Shp2 promotes liver cancer stem cell expansion by augmenting β-catenin signaling and predicts chemotherapeutic response of patients
- (2017) Daimin Xiang et al. HEPATOLOGY
- SHP2 regulates proliferation and tumorigenicity of glioma stem cells
- (2017) Laura Roccograndi et al. JOURNAL OF NEURO-ONCOLOGY
- A Tumor Cell-Selective Inhibitor of Mitogen-Activated Protein Kinase Phosphatases Sensitizes Breast Cancer Cells to Lymphokine-Activated Killer Cell Activity
- (2017) Christof T. Kaltenmeier et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome
- (2017) Zhong Yao et al. MOLECULAR CELL
- Targeting c-FOS and DUSP1 abrogates intrinsic resistance to tyrosine-kinase inhibitor therapy in BCR-ABL-induced leukemia
- (2017) Meenu Kesarwani et al. NATURE MEDICINE
- Secretion-mediated STAT3 activation promotes self-renewal of glioma stem-like cells during hypoxia
- (2017) D A Almiron Bonnin et al. ONCOGENE
- Mutant p53 oncogenic functions in cancer stem cells are regulated by WIP through YAP/TAZ
- (2017) M Escoll et al. ONCOGENE
- Pluripotency markers are differentially induced by MEK inhibition in thyroid and melanoma BRAFV600E cell lines
- (2016) Emma R. Dorris et al. CANCER BIOLOGY & THERAPY
- Protein kinase A catalytic subunit isoform PRKACA; History, function and physiology
- (2016) Rigney E. Turnham et al. GENE
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- (2016) Stephen B. Keysar et al. JNCI-Journal of the National Cancer Institute
- The Hippo pathway in intestinal regeneration and disease
- (2016) Audrey W. Hong et al. Nature Reviews Gastroenterology & Hepatology
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- (2016) Simone Di Franco et al. Oncotarget
- Aldehyde dehydrogenase 1A1 in stem cells and cancer
- (2016) Hiroyuki Tomita et al. Oncotarget
- Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2
- (2016) Stephen B. Keysar et al. JNCI-Journal of the National Cancer Institute
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- (2016) Tara Boulding et al. PLoS One
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- (2016) Meiou Dai et al. Scientific Reports
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- (2015) Uzma Asghar et al. NATURE REVIEWS DRUG DISCOVERY
- Suppression of cancer relapse and metastasis by inhibiting cancer stemness
- (2015) Youzhi Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effects of PI3K inhibitor NVP-BKM120 on overcoming drug resistance and eliminating cancer stem cells in human breast cancer cells
- (2015) Y Hu et al. Cell Death & Disease
- PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype
- (2015) Shunlei Duan et al. Nature Communications
- Selective JAK2/ABL dual inhibition therapy effectively eliminates TKI-insensitive CML stem/progenitor cells
- (2015) Hanyang Lin et al. Oncotarget
- CD44v6 Is a Marker of Constitutive and Reprogrammed Cancer Stem Cells Driving Colon Cancer Metastasis
- (2014) Matilde Todaro et al. Cell Stem Cell
- Discovery and saturation analysis of cancer genes across 21 tumour types
- (2014) Michael S. Lawrence et al. NATURE
- Genetic alterations of protein tyrosine phosphatases in human cancers
- (2014) S Zhao et al. ONCOGENE
- Protein tyrosine phosphatases as novel targets in breast cancer therapy
- (2013) Caroline E. Nunes-Xavier et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Knockdown of dual specificity phosphatase 4 enhances the chemosensitivity of MCF-7 and MCF-7/ADR breast cancer cells to doxorubicin
- (2013) Yu Liu et al. EXPERIMENTAL CELL RESEARCH
- The regulatory roles of phosphatases in cancer
- (2013) J Stebbing et al. ONCOGENE
- Complexity of Receptor Tyrosine Kinase Signal Processing
- (2013) N. Volinsky et al. Cold Spring Harbor Perspectives in Biology
- The Nonreceptor-Type Tyrosine Phosphatase PTPN13 Is a Tumor Suppressor Gene in Non–Small Cell Lung Cancer
- (2012) Marianna Scrima et al. AMERICAN JOURNAL OF PATHOLOGY
- New Directions in Targeting Protein Kinases: Focusing Upon True Allosteric and Bivalent Inhibitors
- (2012) Vandana Lamba et al. CURRENT PHARMACEUTICAL DESIGN
- Dual-specificity MAP kinase phosphatases (MKPs)
- (2012) Christopher J. Caunt et al. FEBS Journal
- The human phosphatase interactome: An intricate family portrait
- (2012) Francesca Sacco et al. FEBS LETTERS
- Genotoxic stress modulates CDC25C phosphatase alternative splicing in human breast cancer cell lines
- (2012) Hélène Albert et al. Molecular Oncology
- Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop
- (2012) Nicola Aceto et al. NATURE MEDICINE
- Upregulation of CXCR4 is functionally crucial for maintenance of stemness in drug-resistant non-small cell lung cancer cells
- (2012) M-J Jung et al. ONCOGENE
- Approaches to discover non-ATP site kinase inhibitors
- (2012) Lori Krim Gavrin et al. MedChemComm
- The Evolution of Protein Kinase Inhibitors from Antagonists to Agonists of Cellular Signaling
- (2011) Arvin C. Dar et al. Annual Review of Biochemistry
- The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors
- (2011) Lauren L.C. Marotta et al. JOURNAL OF CLINICAL INVESTIGATION
- Overexpression of cyclin-dependent kinase-associated protein phosphatase enhances cell proliferation in renal cancer cells
- (2011) Ming-Wei Lai et al. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
- Tyrosine phosphatase PTPRD suppresses colon cancer cell migration in coordination with CD44
- (2011) KOSUKE FUNATO et al. Experimental and Therapeutic Medicine
- Tumorigenic and Metastatic Activity of Human Thyroid Cancer Stem Cells
- (2010) M. Todaro et al. CANCER RESEARCH
- CDC 25A gene 263C/T, -350C/T, and -51C/G polymorphisms in breast carcinoma
- (2010) Isik Didem Karagoz et al. TUMOR BIOLOGY
- The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers
- (2009) S. Veeriah et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A History of Cancer Chemotherapy
- (2008) Vincent T. DeVita et al. CANCER RESEARCH
- Inhibition of GSK3 differentially modulates NF-κB, CREB, AP-1 and β-catenin signaling in hepatocytes, but fails to promote TNF-α-induced apoptosis
- (2008) Frank Götschel et al. EXPERIMENTAL CELL RESEARCH
- The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations
- (2008) A. Dubrovska et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Multiple pathways regulated by the tumor suppressor PP2A in transformation
- (2008) Jukka Westermarck et al. TRENDS IN MOLECULAR MEDICINE
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