Identification of 14 Differentially-Expressed Metabolism-Related Genes as Potential Targets of Gastric Cancer by Integrated Proteomics and Transcriptomics

A retrospective overview of PHGDH and its inhibitors for regulating cancer metabolism

(2021) Jia-Ying Zhao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Targeted Glucose or Glutamine Metabolic Therapy Combined With PD-1/PD-L1 Checkpoint Blockade Immunotherapy for the Treatment of Tumors - Mechanisms and Strategies

(2021) Guofeng Ma et al.   Frontiers in Oncology

Emerging Roles for Branched-Chain Amino Acid Metabolism in Cancer

(2020) Sharanya Sivanand et al.   CANCER CELL

The KRAS-BCAA-BCAT2 axis in PDAC development

(2020) Mattia Falcone et al.   NATURE CELL BIOLOGY

BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma

(2020) Jin-Tao Li et al.   NATURE CELL BIOLOGY

Cancer registration in China and its role in cancer prevention and control

(2020) Wenqiang Wei et al.   LANCET ONCOLOGY

Branched-chain amino acid aminotransferase 2 regulates ferroptotic cell death in cancer cells

(2020) Kang Wang et al.   CELL DEATH AND DIFFERENTIATION

Deep undepleted human serum proteome profiling toward biomarker discovery for Alzheimer’s disease

(2019) Kaushik Kumar Dey et al.   Clinical Proteomics

Arginine: Challenges and opportunities of this two-faced molecule in cancer therapy

(2018) Mozhgan Jahani et al.   BIOMEDICINE & PHARMACOTHERAPY

Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression

(2018) Jingjing Cong et al.   Cell Metabolism

Argininosuccinate synthetase 1 contributes to gastric cancer invasion and progression by modulating autophagy

(2018) Chung-Ying Tsai et al.   FASEB JOURNAL

Global surveillance of trends in cancer survival 2000–14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries

(2018) Claudia Allemani et al.   LANCET

Reverse engineering the cancer metabolic network using flux analysis to understand drivers of human disease

(2018) Mehmet G. Badur et al.   METABOLIC ENGINEERING

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

(2018) Róisín M. Loftus et al.   Nature Communications

Branched Chain Amino Acids

(2018) Michael Neinast et al.   Annual Review of Physiology

Reimagining IDO Pathway Inhibition in Cancer Immunotherapy via Downstream Focus on the Tryptophan–Kynurenine–Aryl Hydrocarbon Axis

(2018) Brian W. Labadie et al.   CLINICAL CANCER RESEARCH

Gastric cancer: Metabolic and metabolomics perspectives (Review)

(2017) Shiyu Xiao et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Amino-acid transporters in T-cell activation and differentiation

(2017) Wenkai Ren et al.   Cell Death & Disease

PKM2 promotes cell migration and inhibits autophagy by mediating PI3K/AKT activation and contributes to the malignant development of gastric cancer

(2017) Chao Wang et al.   Scientific Reports

L-Arginine supplementation inhibits the growth of breast cancer by enhancing innate and adaptive immune responses mediated by suppression of MDSCs in vivo

(2016) Yu Cao et al.   BMC CANCER

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity

(2016) Roger Geiger et al.   CELL

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation

(2016) Noga Ron-Harel et al.   Cell Metabolism

Metabolic Reprogramming Supports IFN-γ Production by CD56brightNK Cells

(2016) Sinéad E. Keating et al.   JOURNAL OF IMMUNOLOGY

Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy

(2016) Mahima Swamy et al.   NATURE IMMUNOLOGY

Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers

(2016) J. R. Mayers et al.   SCIENCE

The Warburg Effect: How Does it Benefit Cancer Cells?

(2016) Maria V. Liberti et al.   TRENDS IN BIOCHEMICAL SCIENCES

Phosphoglycerate dehydrogenase is a novel predictor for poor prognosis in gastric cancer

(2016) Han Wu et al.   OncoTargets and Therapy

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses

(2015) Ping-Chih Ho et al.   CELL

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

(2015) Chih-Hao Chang et al.   CELL

Genetics and Molecular Pathogenesis of Gastric Adenocarcinoma

(2015) Patrick Tan et al.   GASTROENTEROLOGY

Immunometabolism governs dendritic cell and macrophage function

(2015) Luke A.J. O’Neill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Metabolic pathways promoting cancer cell survival and growth

(2015) Lindsey K. Boroughs et al.   NATURE CELL BIOLOGY

Big opportunities for small molecules in immuno-oncology

(2015) Jerry L. Adams et al.   NATURE REVIEWS DRUG DISCOVERY

Sestrin2 is a leucine sensor for the mTORC1 pathway

(2015) R. L. Wolfson et al.   SCIENCE

Mitochondrial dysfunction in cancer chemoresistance

(2014) Nicoletta Guaragnella et al.   BIOCHEMICAL PHARMACOLOGY

Elevated levels of serum fatty acid synthase in patients with gastric carcinoma

(2014) TOMOAKI ITO et al.   Oncology Letters

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

(2013) Jaekyoung Son et al.   NATURE

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

(2012) Haoqiang Ying et al.   CELL

Differential Proteomic Analysis of Noncardia Gastric Cancer from Individuals of Northern Brazil

(2012) Mariana Ferreira Leal et al.   PLoS One

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth

(2011) D. Gaglio et al.   Molecular Systems Biology

Androgen-Regulated Expression of Arginase 1, Arginase 2 and Interleukin-8 in Human Prostate Cancer

(2010) Philippe O. Gannon et al.   PLoS One

Effect of arginase II on L-arginine depletion and cell growth in murine cell lines of renal cell carcinoma

(2008) David J Tate et al.   Journal of Hematology & Oncology