Current status of beta‐thalassemia and its treatment strategies

Cardioprotective Potential of Iron Chelators and Prochelators

(2019) Hana Jansová et al.   CURRENT MEDICINAL CHEMISTRY

PREGNANCY IN THALASSEMIA

(2019) Raffaella Origa et al.   Mediterranean Journal of Hematology and Infectious Diseases

Iron chelation by deferasirox confers protection against concanavalin A-induced liver fibrosis: A mechanistic approach

(2019) Nada Adel et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Molecular basis of β thalassemia and potential therapeutic targets

(2018) Swee Lay Thein   BLOOD CELLS MOLECULES AND DISEASES

Hepatocellular Carcinoma in β-Thalassemia Patients: Review of the Literature with Molecular Insight into Liver Carcinogenesis

(2018) Antoine Finianos et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Global analysis of erythroid cells redox status reveals the involvement of Prdx1 and Prdx2 in the severity of beta thalassemia

(2018) Karen S. Romanello et al.   PLoS One

The Impact of Transfusion and Chelation on Oxidative Stress in Immigrant Syrian Children with β-Thalassemia

(2017) Meriç Kaymak Cihan et al.   INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION

Thalassemias in South Asia: clinical lessons learnt from Bangladesh

(2017) Mohammad Sorowar Hossain et al.   Orphanet Journal of Rare Diseases

The Impact of Transfusion and Chelation on Oxidative Stress in Immigrant Syrian Children with β-Thalassemia

(2017) Meriç Kaymak Cihan et al.   Indian Journal of Hematology and Blood Transfusion

The start-up of the first hematopoietic stem cell transplantation center in the Iraqi Kurdistan: a capacity-building cooperative project by the Hiwa Cancer Hospital, Sulaymaniyah, and the Italian Agency for Development Cooperation.

(2017) Ignazio Majolino   Mediterranean Journal of Hematology and Infectious Diseases

Comparison of different methods for erythroid differentiation in the K562 cell line

(2016) Laleh Shariati et al.   BIOTECHNOLOGY LETTERS

A randomized trial of amlodipine in addition to standard chelation therapy in patients with thalassemia major

(2016) J. L. Fernandes et al.   BLOOD

Induced pluripotent stem cells in Alzheimer’s disease: applications for disease modeling and cell-replacement therapy

(2016) Juan Yang et al.   Molecular Neurodegeneration

Normal hemostatic parameters in children and young adults with α-thalassemia diseases

(2016) Nongnuch Sirachainan et al.   THROMBOSIS RESEARCH

Alpha hemoglobin stabilizing protein: Its causal relationship with the severity of beta thalassemia

(2015) Chandan S. Sagar et al.   BLOOD CELLS MOLECULES AND DISEASES

Ineffective erythropoiesis and regulation of iron status in iron loading anaemias

(2015) Clara Camaschella et al.   BRITISH JOURNAL OF HAEMATOLOGY

New insights into iron regulation and erythropoiesis

(2015) Airie Kim et al.   CURRENT OPINION IN HEMATOLOGY

Cell signaling pathways involved in drug-mediated fetal hemoglobin induction: Strategies to treat sickle cell disease

(2015) Betty S Pace et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Vascular Dysfunction in Patients With Young β-Thalassemia

(2014) Amira Abdel Moneam Adly et al.   CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS

Hematopoietic stem cell transplantation in thalassemia major and sickle cell disease: indications and management recommendations from an international expert panel

(2014) E. Angelucci et al.   HAEMATOLOGICA

Molecular Characterization of α- and β-Thalassaemia among Malay Patients

(2014) Nur Yatim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

LONGITUDINAL STUDY ON LIVER FUNCTIONS IN PATIENTS WITH THALASSEMIA MAJOR BEFORE AND AFTER DEFERASIROX (DFX) THERAPY

(2014) Ashraf Tawfik Soliman et al.   Mediterranean Journal of Hematology and Infectious Diseases

Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice

(2013) S. S. Franco et al.   HAEMATOLOGICA

Differential Thermal Stability and Oxidative Vulnerability of the Hemoglobin Variants, HbA2 and HbE

(2013) Abhijit Chakrabarti et al.   PLoS One

Allogeneic hematopoietic stem cell transplantation in thalassemia major: results of a reduced-toxicity conditioning regimen based on the use of treosulfan

(2012) M. E. Bernardo et al.   BLOOD

Hb E/β-Thalassemia: The Second Most Common Cause of Transfusion-Dependent Thalassemia in the Gwalior-Chambal Region of Central India

(2012) Rakesh Kumar et al.   HEMOGLOBIN

ZIP8 Is an Iron and Zinc Transporter Whose Cell-surface Expression Is Up-regulated by Cellular Iron Loading

(2012) Chia-Yu Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-transferrin bound iron: A key role in iron overload and iron toxicity

(2011) Pierre Brissot et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Optimal management of β thalassaemia intermedia

(2011) Ali T. Taher et al.   BRITISH JOURNAL OF HAEMATOLOGY

Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload

(2011) Gloria C. Preza et al.   JOURNAL OF CLINICAL INVESTIGATION

Treatment options for thalassemia patients with osteoporosis

(2010) Evangelos Terpos et al.   Annals of the New York Academy of Sciences

A preclinical approach for gene therapy of β-thalassemia

(2010) Laura Breda et al.   Annals of the New York Academy of Sciences

Pathogenesis and management of iron toxicity in thalassemia

(2010) Chaim Hershko   Annals of the New York Academy of Sciences

Hepcidin and Disorders of Iron Metabolism

(2010) Tomas Ganz et al.   Annual Review of Medicine

Therapeutic levels of fetal hemoglobin in erythroid progeny of  -thalassemic CD34+ cells after lentiviral vector-mediated gene transfer

(2010) A. Wilber et al.   BLOOD

The inherited diseases of hemoglobin are an emerging global health burden

(2010) D. J. Weatherall   BLOOD

HLA-matched sibling bone marrow transplantation for  -thalassemia major

(2010) M. Sabloff et al.   BLOOD

Beta-thalassemia

(2010) Renzo Galanello et al.   Orphanet Journal of Rare Diseases

Separating Thalassemia Trait and Iron Deficiency by Even Simpler Inspection

(2009) Graham Gibbs   AMERICAN JOURNAL OF CLINICAL PATHOLOGY