Proliferating CD8+ T Cell Infiltrates Are Associated with Improved Survival in Glioblastoma

Key chemokines direct migration of immune cells in solid tumors

(2021) Karan Kohli et al.   CANCER GENE THERAPY

STINGing the Tumor Microenvironment to Promote Therapeutic Tertiary Lymphoid Structure Development

(2021) Jessica N. Filderman et al.   Frontiers in Immunology

Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma

(2021) Luuk van Hooren et al.   Nature Communications

Heterogeneity in tertiary lymphoid structure B-cells correlates with patient survival in metastatic melanoma

(2021) Kevin T Lynch et al.   Journal for ImmunoTherapy of Cancer

New predictors for immunotherapy responses sharpen our view of the tumour microenvironment

(2020) Tullia C. Bruno   NATURE

Tertiary lymphoid structures improve immunotherapy and survival in melanoma

(2020) Rita Cabrita et al.   NATURE

B cells and tertiary lymphoid structures promote immunotherapy response

(2020) Beth A. Helmink et al.   NATURE

Revisiting the role of CD4+ T cells in cancer immunotherapy—new insights into old paradigms

(2020) Rong En Tay et al.   CANCER GENE THERAPY

Diffuse gliomas to date and beyond 2016 WHO Classification of Tumours of the Central Nervous System

(2020) Hiromi Onizuka et al.   International Journal of Clinical Oncology

Single-Cell Atlas Reveals Complexity of the Immunosuppressive Microenvironment of Initial and Recurrent Glioblastoma

(2020) Weilun Fu et al.   Frontiers in Immunology

The Roles of CD8+ T Cell Subsets in Antitumor Immunity

(2020) Michael St. Paul et al.   TRENDS IN CELL BIOLOGY

Prognostic value of tertiary lymphoid structure and tumour infiltrating lymphocytes in oral squamous cell carcinoma

(2020) Qunxing Li et al.   International Journal of Oral Science

Roles of IFN-γ in tumor progression and regression: a review

(2020) Dragica Jorgovanovic et al.   Biomarker Research

Cytokine and Chemokine Signals of T-Cell Exclusion in Tumors

(2020) Yu Zhang et al.   Frontiers in Immunology

Dexamethasone in Glioblastoma Multiforme Therapy: Mechanisms and Controversies

(2019) Marta Cenciarini et al.   Frontiers in Molecular Neuroscience

Consequences of IDH1/2 Mutations in Gliomas and an Assessment of Inhibitors Targeting Mutated IDH Proteins

(2019) Bozena Kaminska et al.   MOLECULES

The B-side of Cancer Immunity: The Underrated Tune

(2019) Largeot et al.   Cells

Immune Cell Infiltration and Tertiary Lymphoid Structures as Determinants of Antitumor Immunity

(2018) Victor H. Engelhard et al.   JOURNAL OF IMMUNOLOGY

Lymphoid aggregates in desmoplastic melanoma have features of tertiary lymphoid structures

(2018) Anne M. Stowman et al.   MELANOMA RESEARCH

Correlation between lower balance of Th2 helper T-cells and expression of PD-L1/PD-1 axis genes enables prognostic prediction in patients with glioblastoma

(2018) Yasuo Takashima et al.   Oncotarget

Interferon-Gamma at the Crossroads of Tumor Immune Surveillance or Evasion

(2018) Flávia Castro et al.   Frontiers in Immunology

Dexamethasone-induced immunosuppression: mechanisms and implications for immunotherapy

(2018) Amber J. Giles et al.   Journal for ImmunoTherapy of Cancer

OUP accepted manuscript

(2018)   NEURO-ONCOLOGY

The IFN-γ/PD-L1 axis between T cells and tumor microenvironment: hints for glioma anti-PD-1/PD-L1 therapy

(2018) Jiawen Qian et al.   Journal of Neuroinflammation

Human regulatory B cells in health and disease: therapeutic potential

(2017) Claudia Mauri et al.   JOURNAL OF CLINICAL INVESTIGATION

The immune contexture in cancer prognosis and treatment

(2017) Wolf H. Fridman et al.   Nature Reviews Clinical Oncology

Tumour-associated microglia/macrophages predict poor prognosis in high-grade gliomas and correlate with an aggressive tumour subtype

(2017) M. D. Sørensen et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Heterogeneity of tumor-infiltrating lymphocytes ascribed to local immune status rather than neoantigens by multi-omics analysis of glioblastoma multiforme

(2017) Lin Feng et al.   Scientific Reports

Immune classifications with cytotoxic CD8+ and Th17 infiltrates are predictors of clinical prognosis in glioblastoma

(2017) Rachid Madkouri et al.   OncoImmunology

Corticosteroids compromise survival in glioblastoma

(2016) Kenneth L. Pitter et al.   BRAIN

Tumor infiltrating immune cells in gliomas and meningiomas

(2016) Patrícia Domingues et al.   BRAIN BEHAVIOR AND IMMUNITY

The Emerging Role of B Cells in Tumor Immunity

(2016) Peiling Tsou et al.   CANCER RESEARCH

Dual Faces of IFN  in Cancer Progression: A Role of PD-L1 Induction in the Determination of Pro- and Antitumor Immunity

(2016) M. Mandai et al.   CLINICAL CANCER RESEARCH

Tertiary lymphoid structures, drivers of the anti-tumor responses in human cancers

(2016) Marie-Caroline Dieu-Nosjean et al.   IMMUNOLOGICAL REVIEWS

Tertiary Lymphoid Organs in Cancer Tissues

(2016) Nobuyoshi Hiraoka et al.   Frontiers in Immunology

Tertiary Lymphoid Structures in Cancers: Prognostic Value, Regulation, and Manipulation for Therapeutic Intervention

(2016) Catherine Sautès-Fridman et al.   Frontiers in Immunology

Increased proportion of FoxP3+ regulatory T cells in tumor infiltrating lymphocytes is associated with tumor recurrence and reduced survival in patients with glioblastoma

(2015) Elias J. Sayour et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

TLR2/6 agonists and interferon-gamma induce human melanoma cells to produce CXCL10

(2015) Ileana S. Mauldin et al.   INTERNATIONAL JOURNAL OF CANCER

PD-L1 expression and prognostic impact in glioblastoma

(2015) Edjah K. Nduom et al.   NEURO-ONCOLOGY

Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases

(2015) Anna S Berghoff et al.   OncoImmunology

Tumour-infiltrating CD4+ and CD8+ lymphocytes as predictors of clinical outcome in glioma

(2014) S Han et al.   BRITISH JOURNAL OF CANCER

Th17 Cells in Cancer: The Ultimate Identity Crisis

(2014) Stefanie R. Bailey et al.   Frontiers in Immunology

IDH1 and IDH2 Mutations in Gliomas

(2013) Adam L. Cohen et al.   Current Neurology and Neuroscience Reports

Elevated CD3+ and CD8+ tumor-infiltrating immune cells correlate with prolonged survival in glioblastoma patients despite integrated immunosuppressive mechanisms in the tumor microenvironment and at the systemic level

(2013) Justyna Kmiecik et al.   JOURNAL OF NEUROIMMUNOLOGY

The Role and Regulation of Human Th17 Cells in Tumor Immunity

(2012) Jian Ye et al.   AMERICAN JOURNAL OF PATHOLOGY

Immunotype and Immunohistologic Characteristics of Tumor-Infiltrating Immune Cells Are Associated with Clinical Outcome in Metastatic Melanoma

(2012) G. Erdag et al.   CANCER RESEARCH

Glioblastoma: Clinical characteristics, prognostic factors and survival in 492 patients

(2012) Andreas M. Stark et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

The prognostic influence of tumour-infiltrating lymphocytes in cancer: a systematic review with meta-analysis

(2011) M J M Gooden et al.   BRITISH JOURNAL OF CANCER

Tumour-infiltrating T-cell subpopulations in glioblastomas

(2011) Young-Hee Kim et al.   BRITISH JOURNAL OF NEUROSURGERY

Th17 cells in cancer: help or hindrance?

(2011) Cailin Moira Wilke et al.   CARCINOGENESIS

Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF- 

(2011) J. Lohr et al.   CLINICAL CANCER RESEARCH

CD8+ T-cell infiltrate in newly diagnosed glioblastoma is associated with long-term survival

(2010) Isaac Yang et al.   JOURNAL OF CLINICAL NEUROSCIENCE

T-bet and Eomesodermin Are Required for T Cell-Mediated Antitumor Immune Responses

(2010) Y. Zhu et al.   JOURNAL OF IMMUNOLOGY

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Immune infiltration in human tumors: a prognostic factor that should not be ignored

(2009) F Pagès et al.   ONCOGENE

Long-Term Survival for Patients With Non–Small-Cell Lung Cancer With Intratumoral Lymphoid Structures

(2008) Marie-Caroline Dieu-Nosjean et al.   JOURNAL OF CLINICAL ONCOLOGY

Nomograms for predicting survival of patients with newly diagnosed glioblastoma: prognostic factor analysis of EORTC and NCIC trial 26981-22981/CE.3

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