Single-Cell Atlas Reveals Complexity of the Immunosuppressive Microenvironment of Initial and Recurrent Glioblastoma

Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma

(2019) Timothy F. Cloughesy et al.   NATURE MEDICINE

CD8+ T cell exhaustion

(2019) Makoto Kurachi   Seminars in Immunopathology

Lipopolysaccharide inhalation recruits monocytes and dendritic cell subsets to the alveolar airspace

(2019) Laura Jardine et al.   Nature Communications

Differential microglia and macrophage profiles in human IDH-mutant and -wild type glioblastoma

(2019) Candice C. Poon et al.   Oncotarget

A Homeostatic Arid1a-Dependent Permissive Chromatin State Licenses Hepatocyte Responsiveness to Liver-Injury-Associated YAP Signaling

(2019) Weiping Li et al.   Cell Stem Cell

Immunophenotyping of Newly Diagnosed and Recurrent Glioblastoma Defines Distinct Immune Exhaustion Profiles in Peripheral and Tumor-infiltrating Lymphocytes

(2018) Malte Mohme et al.   CLINICAL CANCER RESEARCH

Mass cytometry: a powerful tool for dissecting the immune landscape

(2018) Yannick Simoni et al.   CURRENT OPINION IN IMMUNOLOGY

When Immune Cells Turn Bad—Tumor-Associated Microglia/Macrophages in Glioma

(2018) Saskia Roesch et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Integrated functional and mass spectrometry-based flow cytometric phenotyping to describe the immune microenvironment in acute myeloid leukemia

(2018) Adam J. Lamble et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes

(2018) Konrad Gabrusiewicz et al.   OncoImmunology

Tumor-Associated Macrophages: Therapeutic Targets for Skin Cancer

(2018) Taku Fujimura et al.   Frontiers in Oncology

Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor

(2018) Huimin Hu et al.   CELL

Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma

(2017) Roger Stupp et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Immune microenvironment of gliomas

(2017) Anna Gieryng et al.   LABORATORY INVESTIGATION

High-dimensional, single-cell characterization of the brain's immune compartment

(2017) Ben Korin et al.   NATURE NEUROSCIENCE

Immunotherapies for malignant glioma

(2017) Vassiliki A. Boussiotis et al.   ONCOGENE

A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma

(2017) Donald M. O’Rourke et al.   Science Translational Medicine

Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human Glioblastoma

(2017) Spyros Darmanis et al.   Cell Reports

Hepatocellular carcinoma repression by TNFα-mediated synergistic lethal effect of mitosis defect-induced senescence and cell death sensitization

(2016) Dan Li et al.   HEPATOLOGY

Bioinformatic profiling identifies an immune-related risk signature for glioblastoma

(2016) Wen Cheng et al.   NEUROLOGY

A comprehensive profile of recurrent glioblastoma

(2016) B Campos et al.   ONCOGENE

Macrophages and cancer: from mechanisms to therapeutic implications

(2015) Renato Ostuni et al.   TRENDS IN IMMUNOLOGY

Comprehensive portrait of recurrent glioblastoma multiforme in molecular and clinical characteristics

(2015) Rui Li et al.   Oncotarget

Immunotherapy for Brain Cancer: Recent Progress and Future Promise

(2014) C. M. Jackson et al.   CLINICAL CANCER RESEARCH

CD4+ /CD8+ double-positive T cells: more than just a developmental stage?

(2014) Nana H. Overgaard et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Gliomas Promote Immunosuppression through Induction of B7-H1 Expression in Tumor-Associated Macrophages

(2013) O. Bloch et al.   CLINICAL CANCER RESEARCH

Normalization of mass cytometry data with bead standards

(2013) Rachel Finck et al.   CYTOMETRY PART A

NK Cells in Central Nervous System Disorders

(2013) A. Poli et al.   JOURNAL OF IMMUNOLOGY

viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia

(2013) El-ad David Amir et al.   NATURE BIOTECHNOLOGY

Increase in tumor-associated macrophages after antiangiogenic therapy is associated with poor survival among patients with recurrent glioblastoma

(2013) C. Lu-Emerson et al.   NEURO-ONCOLOGY

Circulating progenitor cells: a comparison of patients with glioblastoma or meningioma

(2012) George A. Alexiou et al.   ACTA NEUROLOGICA BELGICA

Primary brain tumours in adults

(2012) Damien Ricard et al.   LANCET

Standards of care for treatment of recurrent glioblastoma—are we there yet?

(2012) Michael Weller et al.   NEURO-ONCOLOGY

Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF- 

(2011) J. Lohr et al.   CLINICAL CANCER RESEARCH

Nomenclature of monocytes and dendritic cells in blood

(2010) L. Ziegler-Heitbrock et al.   BLOOD

Substantial reduction of naïve and regulatory T cells following traumatic stress

(2009) Annette Sommershof et al.   BRAIN BEHAVIOR AND IMMUNITY

Natural Killer Cell Accumulation in Tumors Is Dependent on IFN-  and CXCR3 Ligands

(2008) M. Wendel et al.   CANCER RESEARCH