Role of Pancreatic Stellate Cell-Derived Exosomes in Pancreatic Cancer-Related Diabetes: A Novel Hypothesis
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Role of Pancreatic Stellate Cell-Derived Exosomes in Pancreatic Cancer-Related Diabetes: A Novel Hypothesis
Authors
Keywords
-
Journal
Cancers
Volume 13, Issue 20, Pages 5224
Publisher
MDPI AG
Online
2021-10-19
DOI
10.3390/cancers13205224
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway
- (2021) Wenpeng Cao et al. Aging-US
- Exosomal integrins and their influence on pancreatic cancer progression and metastasis
- (2021) Ilaria Casari et al. CANCER LETTERS
- Upregulation of exosomal microRNA‑21 in pancreatic stellate cells promotes pancreatic cancer cell migration and enhances Ras/ERK pathway activity
- (2020) Qiang Ma et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Clinicopathological features of pancreatic cancer-related diabetes.
- (2020) Michael Lee et al. JOURNAL OF CLINICAL ONCOLOGY
- Pancreatic stellate cells: Aiding and abetting pancreatic cancer progression
- (2020) Srinivasa P. Pothula et al. PANCREATOLOGY
- The biology, function, and biomedical applications of exosomes
- (2020) Raghu Kalluri et al. SCIENCE
- 1133 PANCREATIC STELLATE CELL AND CANCER CELL DERIVED EXOSOMES IMPAIR BETA CELL FUNCTION: IMPLICATIONS FOR PANCREATIC CANCER RELATED DIABETES.
- (2020) Chamini Perera et al. GASTROENTEROLOGY
- Pancreatic stellate cells derived exosomal miR-5703 promotes pancreatic cancer by downregulating CMTM4 and activating PI3K/Akt pathway
- (2020) Mingzhe Li et al. CANCER LETTERS
- 2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2021
- (2020) DIABETES CARE
- Phases of Metabolic and Soft Tissue Changes in Months Preceding a Diagnosis of Pancreatic Ductal Adenocarcinoma
- (2019) Raghuwansh P. Sah et al. GASTROENTEROLOGY
- Oncogenic and Non‐Malignant Pancreatic Exosome Cargo Reveal Distinct Expression of Oncogenic and Prognostic Factors Involved in Tumour Invasion and Metastasis
- (2019) Aikaterini Emmanouilidi et al. PROTEOMICS
- Early Detection of Pancreatic Cancer: Opportunities and Challenges
- (2019) Aatur D. Singhi et al. GASTROENTEROLOGY
- Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in cell transformation
- (2019) Karoliina Stefanius et al. eLife
- Plasma extracellular vesicle long RNA profiling identifies a diagnostic signature for the detection of pancreatic ductal adenocarcinoma
- (2019) Shulin Yu et al. GUT
- The intricate relationship between diabetes, obesity and pancreatic cancer
- (2019) Silvano Paternoster et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Mechanism of recipient cell-dependent differences in exosome uptake
- (2018) Sayo Horibe et al. BMC CANCER
- Model to Determine Risk of Pancreatic Cancer in Patients with New-onset Diabetes
- (2018) Ayush Sharma et al. GASTROENTEROLOGY
- Downregulated miR-98-5p promotes PDAC proliferation and metastasis by reversely regulating MAP4K4
- (2018) Yue Fu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Pancreatic Cancer Following Incident Diabetes in African Americans and Latinos: The Multiethnic Cohort
- (2018) Veronica Wendy Setiawan et al. JNCI-Journal of the National Cancer Institute
- The critical roles of activated stellate cells-mediated paracrine signaling, metabolism and onco-immunology in pancreatic ductal adenocarcinoma
- (2018) Yaojie Fu et al. Molecular Cancer
- Tumor-derived exosomal lnc-Sox2ot promotes EMT and stemness by acting as a ceRNA in pancreatic ductal adenocarcinoma
- (2018) Zhonghu Li et al. ONCOGENE
- Pancreatic Cancer Following Incident Diabetes in African Americans and Latinos: The Multiethnic Cohort
- (2018) Veronica Wendy Setiawan et al. JNCI-Journal of the National Cancer Institute
- Extracellular vesicles are increased in the serum of children with autism spectrum disorder, contain mitochondrial DNA, and stimulate human microglia to secrete IL-1β
- (2018) Irene Tsilioni et al. Journal of Neuroinflammation
- Mechanisms of Insulin Action and Insulin Resistance
- (2018) Max C. Petersen et al. PHYSIOLOGICAL REVIEWS
- Inter- and intra-tumoral heterogeneity in cancer-associated fibroblasts of human pancreatic ductal adenocarcinoma
- (2018) Cindy Neuzillet et al. JOURNAL OF PATHOLOGY
- Pancreatic stellate cells facilitate pancreatic cancer cell viability and invasion
- (2018) Shang‑Long Liu et al. Oncology Letters
- A Clinical Prediction Model to Assess Risk for Pancreatic Cancer Among Patients With New-Onset Diabetes
- (2017) Ben Boursi et al. GASTROENTEROLOGY
- Exosomal adrenomedullin derived from cancer-associated fibroblasts promotes lipolysis in adipose tissue
- (2017) Fanyang Kong et al. GUT
- Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
- (2017) Daniel Öhlund et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Exosomes Derived From Pancreatic Stellate Cells
- (2017) Tetsuya Takikawa et al. PANCREAS
- The role of exosomes in cancer metastasis
- (2017) Teresa Bernadette Steinbichler et al. SEMINARS IN CANCER BIOLOGY
- Association of elevated risk of pancreatic cancer in diabetic patients: A systematic review and meta-analysis
- (2017) Jiaxin Tan et al. Oncology Letters
- Plasma exosome miR-196a and miR-1246 are potential indicators of localized pancreatic cancer
- (2017) Yi-Fan Xu et al. Oncotarget
- Targeting the HGF/c-MET pathway: stromal remodelling in pancreatic cancer
- (2017) Srinivasa P. Pothula et al. Oncotarget
- Exosomes derived from pancreatic cancer cells induce insulin resistance in C2C12 myotube cells through the PI3K/Akt/FoxO1 pathway
- (2017) Lantian Wang et al. Scientific Reports
- Insulin promotes proliferation and fibrosing responses in activated pancreatic stellate cells
- (2016) Jiayue Yang et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Hepatocyte growth factor inhibition: a novel therapeutic approach in pancreatic cancer
- (2016) Srinivasa P Pothula et al. BRITISH JOURNAL OF CANCER
- Key role of pancreatic stellate cells in pancreatic cancer
- (2016) Srinivasa P. Pothula et al. CANCER LETTERS
- Isolation and characterization of human islet stellate cells
- (2016) Min Zha et al. EXPERIMENTAL CELL RESEARCH
- Extracellular vesicle isolation and characterization: toward clinical application
- (2016) Rong Xu et al. JOURNAL OF CLINICAL INVESTIGATION
- Prognostic relevance of preoperative diabetes mellitus and the degree of hyperglycemia on the outcomes of resected pancreatic ductal adenocarcinoma
- (2016) Woohyung Lee et al. JOURNAL OF SURGICAL ONCOLOGY
- A multipronged approach to pancreatic cancer treatment
- (2016) Minoti V. Apte et al. Nature Reviews Gastroenterology & Hepatology
- Exosome-Mediated Metastasis: From Epithelial–Mesenchymal Transition to Escape from Immunosurveillance
- (2016) Nicholas Syn et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Non-coding RNAs in pancreatic cancer: challenges and opportunities for clinical application
- (2016) V. Taucher et al. CELLULAR ONCOLOGY
- Immunosuppressive CD14+HLA-DRlo/neg monocytes are elevated in pancreatic cancer and “primed” by tumor-derived exosomes
- (2016) Naureen Javeed et al. OncoImmunology
- Pancreatic cancer
- (2016) Jorg Kleeff et al. Nature Reviews Disease Primers
- Label-Free Nanoplasmonic-Based Short Noncoding RNA Sensing at Attomolar Concentrations Allows for Quantitative and Highly Specific Assay of MicroRNA-10b in Biological Fluids and Circulating Exosomes
- (2015) Gayatri K. Joshi et al. ACS Nano
- Pancreatic Cancer-Associated Diabetes Is an "Exosomopathy"
- (2015) M. Korc CLINICAL CANCER RESEARCH
- Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer
- (2015) Nagaraj S. Nagathihalli et al. GASTROENTEROLOGY
- Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue
- (2015) Gunisha Sagar et al. GUT
- Exosome mediated communication within the tumor microenvironment
- (2015) Lara Milane et al. JOURNAL OF CONTROLLED RELEASE
- Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
- (2015) Sonia A. Melo et al. NATURE
- Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis
- (2015) Miranda Y. Fong et al. NATURE CELL BIOLOGY
- Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
- (2015) Bruno Costa-Silva et al. NATURE CELL BIOLOGY
- Cancer-Stellate Cell Interactions Perpetuate the Hypoxia-Fibrosis Cycle in Pancreatic Ductal Adenocarcinoma
- (2015) Mert Erkan et al. NEOPLASIA
- Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma
- (2014) Andrew D. Rhim et al. CANCER CELL
- The Early Detection of Pancreatic Cancer: What Will It Take to Diagnose and Treat Curable Pancreatic Neoplasia?
- (2014) A. M. Lennon et al. CANCER RESEARCH
- Pancreatic Cancer-Derived Exosomes Cause Paraneoplastic -cell Dysfunction
- (2014) N. Javeed et al. CLINICAL CANCER RESEARCH
- Stromal response to Hedgehog signaling restrains pancreatic cancer progression
- (2014) J. J. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Isolation and characterization of islet stellate cells in rat
- (2014) Min Zha et al. Islets
- Stars and stripes in pancreatic cancer: role of stellate cells and stroma in cancer progression
- (2014) Jeremy S. Wilson et al. Frontiers in Physiology
- Connective tissue growth factor (CCN2) and microRNA-21 are components of a positive feedback loop in pancreatic stellate cells (PSC) during chronic pancreatitis and are exported in PSC-derived exosomes
- (2014) Alyssa Charrier et al. Journal of Cell Communication and Signaling
- Pancreatic stellate cells reduce insulin expression and induce apoptosis in pancreatic β-cells
- (2013) Kazuhiro Kikuta et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Oxidative stress plays a role in high glucose-induced activation of pancreatic stellate cells
- (2013) Gyeong Ryul Ryu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A Starring Role for Stellate Cells in the Pancreatic Cancer Microenvironment
- (2013) Minoti V. Apte et al. GASTROENTEROLOGY
- Exosomes in tumor microenvironment influence cancer progression and metastasis
- (2013) Christoph Kahlert et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Hyperglycemia, Insulin Resistance, Impaired Pancreatic β-Cell Function, and Risk of Pancreatic Cancer
- (2013) Brian M. Wolpin et al. JNCI-Journal of the National Cancer Institute
- New insights into pancreatic cancer-induced paraneoplastic diabetes
- (2013) Raghuwansh P. Sah et al. Nature Reviews Gastroenterology & Hepatology
- Neoplastic Reprogramming of Patient-Derived Adipose Stem Cells by Prostate Cancer Cell-Associated Exosomes
- (2013) Zakaria Y. Abd Elmageed et al. STEM CELLS
- Analysis of serum exosomal microRNAs and clinicopathologic features of patients with pancreatic adenocarcinoma
- (2013) Risheng Que et al. World Journal of Surgical Oncology
- Adrenomedullin is Up-regulated in Patients With Pancreatic Cancer and Causes Insulin Resistance in β Cells and Mice
- (2012) Gaurav Aggarwal et al. GASTROENTEROLOGY
- Prevalence of Diabetes Mellitus in Pancreatic Cancer Compared to Common Cancers
- (2012) Gaurav Aggarwal et al. PANCREAS
- Antioxidant treatment may protect pancreatic beta cells through the attenuation of islet fibrosis in an animal model of type 2 diabetes
- (2011) Esder Lee et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Conophylline Suppresses Pancreatic Stellate Cells and Improves Islet Fibrosis in Goto-Kakizaki Rats
- (2011) Rie Saito et al. ENDOCRINOLOGY
- Diabetes mellitus and risk of pancreatic cancer: A meta-analysis of cohort studies
- (2011) Qiwen Ben et al. EUROPEAN JOURNAL OF CANCER
- Weight Loss Precedes Cancer-Specific Symptoms in Pancreatic Cancer-Associated Diabetes Mellitus
- (2011) Phil A. Hart et al. PANCREAS
- Novel Blood Biomarkers of Pancreatic Cancer–Associated Diabetes Mellitus Identified by Peripheral Blood–Based Gene Expression Profiles
- (2010) Hai Huang et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Role of Pancreatic Stellate Cells in Pancreatic Cancer Metastasis
- (2010) Zhihong Xu et al. AMERICAN JOURNAL OF PATHOLOGY
- Bone marrow-derived pancreatic stellate cells in rats
- (2010) Gisela Sparmann et al. CELL RESEARCH
- CD10+ Pancreatic Stellate Cells Enhance the Progression of Pancreatic Cancer
- (2010) Naoki Ikenaga et al. GASTROENTEROLOGY
- CCK1 and CCK2 Receptors Are Expressed on Pancreatic Stellate Cells and Induce Collagen Production
- (2010) Marc J. Berna et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Pancreatic stellate cells produce acetylcholine and may play a role in pancreatic exocrine secretion
- (2010) P. A. Phillips et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Islet-derived stellate-like cells as a novel source for islet neogenesis in chicks
- (2009) S. P. Datar et al. POULTRY SCIENCE
- Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression
- (2008) R. F. Hwang et al. CANCER RESEARCH
- Prevalence and Clinical Profile of Pancreatic Cancer–Associated Diabetes Mellitus
- (2008) Rahul Pannala et al. GASTROENTEROLOGY
- New-onset diabetes: a potential clue to the early diagnosis of pancreatic cancer
- (2008) Rahul Pannala et al. LANCET ONCOLOGY
- Comparative lesion sequencing provides insights into tumor evolution
- (2008) S. Jones et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pancreatic Cancer–Associated Diabetes Mellitus: Prevalence and Temporal Association With Diagnosis of Cancer
- (2007) Suresh T. Chari et al. GASTROENTEROLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started