Extracellular vesicles are increased in the serum of children with autism spectrum disorder, contain mitochondrial DNA, and stimulate human microglia to secrete IL-1β
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Title
Extracellular vesicles are increased in the serum of children with autism spectrum disorder, contain mitochondrial DNA, and stimulate human microglia to secrete IL-1β
Authors
Keywords
Autism spectrum disorder, Brain, Exosomes, Extracellular vesicles, Inflammation, IL-1β, Microglia, Mitochondrial DNA
Journal
Journal of Neuroinflammation
Volume 15, Issue 1, Pages -
Publisher
Springer Nature America, Inc
Online
2018-08-28
DOI
10.1186/s12974-018-1275-5
References
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Note: Only part of the references are listed.- The Transport Mechanism of Extracellular Vesicles at the Blood-Brain Barrier
- (2018) Junichi Matsumoto et al. CURRENT PHARMACEUTICAL DESIGN
- The role of exosomes in CNS inflammation and their involvement in multiple sclerosis
- (2017) Igor Selmaj et al. JOURNAL OF NEUROIMMUNOLOGY
- Microglial-derived microparticles mediate neuroinflammation after traumatic brain injury
- (2017) Alok Kumar et al. Journal of Neuroinflammation
- Role of extracellular vesicles in autoimmune diseases
- (2016) Delphine Turpin et al. AUTOIMMUNITY REVIEWS
- Salivary miRNA profiles identify children with autism spectrum disorder, correlate with adaptive behavior, and implicate ASD candidate genes involved in neurodevelopment
- (2016) Steven D. Hicks et al. BMC Pediatrics
- Induction of Microglial Activation by Mediators Released from Mast Cells
- (2016) Xiang Zhang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Emergence of exosomal miRNAs as a diagnostic biomarker for Alzheimer's disease
- (2016) Vo Van Giau et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Neurotensin stimulates sortilin and mTOR in human microglia inhibitable by methoxyluteolin, a potential therapeutic target for autism
- (2016) Arti B. Patel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Atopic diseases and inflammation of the brain in the pathogenesis of autism spectrum disorders
- (2016) T C Theoharides et al. Translational Psychiatry
- Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson’s disease and dementia with Lewy bodies
- (2015) Anne Stuendl et al. BRAIN
- Autism spectrum disorders: from genes to neurobiology
- (2015) A Jeremy Willsey et al. CURRENT OPINION IN NEUROBIOLOGY
- Role of Microglia in Autism: Recent Advances
- (2015) Tomoyuki Takano DEVELOPMENTAL NEUROSCIENCE
- Microvesicles in the brain: Biomarker, messenger or mediator?
- (2015) Chiara Porro et al. JOURNAL OF NEUROIMMUNOLOGY
- Gene hunting in autism spectrum disorder: on the path to precision medicine
- (2015) Daniel H Geschwind et al. LANCET NEUROLOGY
- Immune mediators in the brain and peripheral tissues in autism spectrum disorder
- (2015) Myka L. Estes et al. NATURE REVIEWS NEUROSCIENCE
- Microglia in the pathogenesis of autism spectrum disorders
- (2015) Ryuta Koyama et al. NEUROSCIENCE RESEARCH
- Free Extracellular miRNA Functionally Targets Cells by Transfecting Exosomes from Their Companion Cells
- (2015) Krzysztof Bryniarski et al. PLoS One
- Mechanisms of inflammasome activation: recent advances and novel insights
- (2015) Sivapriya K. Vanaja et al. TRENDS IN CELL BIOLOGY
- Revisiting the Mechanisms of CNS Immune Privilege
- (2015) Antoine Louveau et al. TRENDS IN IMMUNOLOGY
- Intercellular Communication by Extracellular Vesicles and Their MicroRNAs in Asthma
- (2014) Yu Fujita et al. CLINICAL THERAPEUTICS
- A potential function for neuronal exosomes: Sequestering intracerebral amyloid-β peptide
- (2014) Kohei Yuyama et al. FEBS LETTERS
- Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism
- (2014) Simone Gupta et al. Nature Communications
- Elevated serum neurotensin and CRH levels in children with autistic spectrum disorders and tail-chasing Bull Terriers with a phenotype similar to autism
- (2014) I Tsilioni et al. Translational Psychiatry
- Environmental toxicants and autism spectrum disorders: a systematic review
- (2014) D A Rossignol et al. Translational Psychiatry
- The “missing link” in autoimmunity and autism: Extracellular mitochondrial components secreted from activated live mast cells
- (2013) Theoharis C. Theoharides et al. AUTOIMMUNITY REVIEWS
- An Open-Label Pilot Study of a Formulation Containing the Anti-Inflammatory Flavonoid Luteolin and Its Effects on Behavior in Children With Autism Spectrum Disorders
- (2013) Anilia Taliou et al. CLINICAL THERAPEUTICS
- Antigen-specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity
- (2013) Krzysztof Bryniarski et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Autism
- (2013) Meng-Chuan Lai et al. LANCET
- Exosomes: Mediators of Neurodegeneration, Neuroprotection and Therapeutics
- (2013) Anuradha Kalani et al. MOLECULAR NEUROBIOLOGY
- Differential Expression of Exosomal microRNAs in Prefrontal Cortices of Schizophrenia and Bipolar Disorder Patients
- (2013) Meredith G. Banigan et al. PLoS One
- Mitochondrial DAMPs Increase Endothelial Permeability through Neutrophil Dependent and Independent Pathways
- (2013) Shiqin Sun et al. PLoS One
- Biomarkers in autism spectrum disorder: the old and the new
- (2013) Barbara Ruggeri et al. PSYCHOPHARMACOLOGY
- Microglia and mast cells: two tracks on the road to neuroinflammation
- (2012) Stephen D. Skaper et al. FASEB JOURNAL
- Evidence of microglial activation in autism and its possible role in brain underconnectivity
- (2012) Juan I. Rodriguez et al. Neuron Glia Biology
- Mitochondrial DNA and anti-mitochondrial antibodies in serum of autistic children
- (2011) Bodi Zhang et al. Journal of Neuroinflammation
- Horizontal transfer of RNAs: exosomes as mediators of intercellular communication
- (2011) Saraswathi Ramachandran et al. Wiley Interdisciplinary Reviews-RNA
- Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome
- (2010) Paul Ashwood et al. BRAIN BEHAVIOR AND IMMUNITY
- Neurotensin is increased in serum of young children with autistic disorder
- (2010) Asimenia Angelidou et al. Journal of Neuroinflammation
- Medical comorbidities in autism: Challenges to diagnosis and treatment
- (2010) Margaret L. Bauman Neurotherapeutics
- Exosomes: proteomic insights and diagnostic potential
- (2009) Richard J Simpson et al. Expert Review of Proteomics
- Astrocytes and Glioblastoma cells release exosomes carrying mtDNA
- (2009) Michele Guescini et al. JOURNAL OF NEURAL TRANSMISSION
- Epidemiology of Pervasive Developmental Disorders
- (2009) Eric Fombonne PEDIATRIC RESEARCH
- Advances in autism genetics: on the threshold of a new neurobiology
- (2008) Brett S. Abrahams et al. NATURE REVIEWS GENETICS
- Novel therapeutic targets for autism
- (2008) Theoharis C. Theoharides et al. TRENDS IN PHARMACOLOGICAL SCIENCES
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