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Title
Defining NASH from a Multi-Omics Systems Biology Perspective
Authors
Keywords
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Journal
Journal of Clinical Medicine
Volume 10, Issue 20, Pages 4673
Publisher
MDPI AG
Online
2021-10-13
DOI
10.3390/jcm10204673
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Note: Only part of the references are listed.- Ion mobility mass spectrometry in the omics era: Challenges and opportunities for metabolomics and lipidomics
- (2021) Giuseppe Paglia et al. MASS SPECTROMETRY REVIEWS
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- (2021) Joeri Lambrecht et al. Frontiers in Immunology
- Best practices in machine learning for chemistry
- (2021) Nongnuch Artrith et al. Nature Chemistry
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- (2020) Wei Hou et al. BIOSCIENCE REPORTS
- Cilofexor, a Nonsteroidal FXR Agonist, in Non‐Cirrhotic Patients with Nonalcoholic Steatohepatitis: A Phase 2 Randomized Controlled Trial
- (2020) Keyur Patel et al. HEPATOLOGY
- Update on NAFLD genetics: from new variants to the clinic
- (2020) Eric Trépo et al. JOURNAL OF HEPATOLOGY
- Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts
- (2020) Catherine G. Vasilopoulou et al. Nature Communications
- Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis
- (2020) Helene M. Ægidius et al. Scientific Reports
- Biomarker discovery for chronic liver diseases by multi-omics – a preclinical case study
- (2020) Daniel Veyel et al. Scientific Reports
- Nonalcoholic Steatohepatitis
- (2020) Adam C. Sheka et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Advances in non-invasive biomarkers for the diagnosis and monitoring of non-alcoholic fatty liver disease
- (2020) Michelle T. Long et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Efficacy and Safety of Aldafermin, an Engineered FGF19 Analog, in a Randomized, Double-Blind, Placebo-Controlled Trial of Patients With Nonalcoholic Steatohepatitis
- (2020) Stephen A. Harrison et al. GASTROENTEROLOGY
- A lipidome atlas in MS-DIAL 4
- (2020) Hiroshi Tsugawa et al. NATURE BIOTECHNOLOGY
- Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts
- (2020) Naeimeh Atabaki-Pasdar et al. PLOS MEDICINE
- Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection
- (2020) Christoph B. Messner et al. Cell Systems
- Feature-based molecular networking in the GNPS analysis environment
- (2020) Louis-Félix Nothias et al. NATURE METHODS
- Recurrent Topics in Mass Spectrometry-Based Metabolomics and Lipidomics—Standardization, Coverage, and Throughput
- (2020) Evelyn Rampler et al. ANALYTICAL CHEMISTRY
- Multiplatform Approach for Plasma Proteomics: Complementarity of Olink Proximity Extension Assay Technology to Mass Spectrometry-Based Protein Profiling
- (2020) Agnese Petrera et al. JOURNAL OF PROTEOME RESEARCH
- Serum aromatic and branched‐chain amino acids associated with NASH demonstrate divergent associations with serum lipids
- (2020) Vanessa D. Mello et al. LIVER INTERNATIONAL
- Systematic classification of unknown metabolites using high-resolution fragmentation mass spectra
- (2020) Kai Dührkop et al. NATURE BIOTECHNOLOGY
- Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis
- (2020) Olivier Govaere et al. Science Translational Medicine
- Proteomics in Drug Development: The Dawn of a New Era?
- (2019) Maria Frantzi et al. Proteomics Clinical Applications
- SIRIUS 4: a rapid tool for turning tandem mass spectra into metabolite structure information
- (2019) Kai Dührkop et al. NATURE METHODS
- Plasma proteome profiling discovers novel proteins associated with non‐alcoholic fatty liver disease
- (2019) Lili Niu et al. Molecular Systems Biology
- A deep proteome and transcriptome abundance atlas of 29 healthy human tissues
- (2019) Dongxue Wang et al. Molecular Systems Biology
- Lipidomic biomarkers and mechanisms of lipotoxicity in non-alcoholic fatty liver disease
- (2019) Gianluca Svegliati-Baroni et al. FREE RADICAL BIOLOGY AND MEDICINE
- Characterization of Vitamin A Metabolome in Human Livers with and without NAFLD
- (2019) Guo Zhong et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Analysis of 1508 plasma samples by capillary flow data-independent acquisition profiles proteomics of weight loss and maintenance
- (2019) Roland Bruderer et al. MOLECULAR & CELLULAR PROTEOMICS
- CONTROL: A randomized phase 2 study of obeticholic acid and atorvastatin on lipoproteins in nonalcoholic steatohepatitis patients
- (2019) Paul J. Pockros et al. LIVER INTERNATIONAL
- Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis
- (2019) Xuelian Xiong et al. MOLECULAR CELL
- International Ring Trial of a High Resolution Targeted Metabolomics and Lipidomics Platform for Serum and Plasma Analysis
- (2019) J. Will Thompson et al. ANALYTICAL CHEMISTRY
- Coordinated changes of gut microbiome and lipidome differentiates nonalcoholic steatohepatitis (NASH) from isolated steatosis
- (2019) Minyi Qian et al. LIVER INTERNATIONAL
- Genetic contributions to NAFLD: leveraging shared genetics to uncover systems biology
- (2019) Mohammed Eslam et al. Nature Reviews Gastroenterology & Hepatology
- Lipidomics from sample preparation to data analysis: a primer
- (2019) Thomas Züllig et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Non-invasive diagnosis of non-alcoholic steatohepatitis and fibrosis with the use of omics and supervised learning: A proof of concept study
- (2019) Nikolaos Perakakis et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Lipidomic Analysis
- (2018) Michal Holčapek et al. ANALYTICAL CHEMISTRY
- Integrated transcriptomics and metabolomics reveal signatures of lipid metabolism dysregulation in HepaRG liver cells exposed to PCB 126
- (2018) Robin Mesnage et al. ARCHIVES OF TOXICOLOGY
- An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans
- (2018) Adil Mardinoglu et al. Cell Metabolism
- Promises and pitfalls of untargeted metabolomics
- (2018) Ilya Gertsman et al. JOURNAL OF INHERITED METABOLIC DISEASE
- How many human proteoforms are there?
- (2018) Ruedi Aebersold et al. Nature Chemical Biology
- BoxCar acquisition method enables single-shot proteomics at a depth of 10,000 proteins in 100 minutes
- (2018) Florian Meier et al. NATURE METHODS
- Role of Bile Acids in Metabolic Control
- (2018) Antonio Molinaro et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Circulating Phospholipid Patterns in NAFLD Patients Associated with a Combination of Metabolic Risk Factors
- (2018) Shilpa Tiwari-Heckler et al. Nutrients
- Evaluation of Polygenic Determinants of Non-Alcoholic Fatty Liver Disease (NAFLD) By a Candidate Genes Resequencing Strategy
- (2018) Alessia Di Costanzo et al. Scientific Reports
- Risk factors and biomarkers of non-alcoholic fatty liver disease: an observational cross-sectional population survey
- (2018) Xiao-Yu Hu et al. BMJ Open
- Integration of Multi-omics Data from Mouse Diversity Panel Highlights Mitochondrial Dysfunction in Non-alcoholic Fatty Liver Disease
- (2018) Karthickeyan Chella Krishnan et al. Cell Systems
- Systems Analyses Reveal Physiological Roles and Genetic Regulators of Liver Lipid Species
- (2018) Pooja Jha et al. Cell Systems
- Mitochondrial dysfunction-related lipid changes occur in non-alcoholic fatty liver disease progression
- (2018) Kang-Yu Peng et al. JOURNAL OF LIPID RESEARCH
- Lipidomics Reveals a Tissue-Specific Fingerprint
- (2018) Irene Pradas et al. Frontiers in Physiology
- Serum metabolites detect the presence of advanced fibrosis in derivation and validation cohorts of patients with non-alcoholic fatty liver disease
- (2018) Cyrielle Caussy et al. GUT
- Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations
- (2018) Sonya A. MacParland et al. Nature Communications
- Tissue-specific pathways and networks underlying sexual dimorphism in non-alcoholic fatty liver disease
- (2018) Zeyneb Kurt et al. Biology of Sex Differences
- Challenges, progress and promises of metabolite annotation for LC–MS-based metabolomics
- (2018) Romanas Chaleckis et al. CURRENT OPINION IN BIOTECHNOLOGY
- Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis
- (2017) Cristina Alonso et al. GASTROENTEROLOGY
- The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases
- (2017) Naga Chalasani et al. HEPATOLOGY
- Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD
- (2017) Panu K. Luukkonen et al. JOURNAL OF HEPATOLOGY
- Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950–Metabolites in Frozen Human Plasma
- (2017) John A. Bowden et al. JOURNAL OF LIPID RESEARCH
- Complementarity of SOMAscan to LC-MS/MS and RNA-seq for quantitative profiling of human embryonic and mesenchymal stem cells
- (2017) Anja M. Billing et al. Journal of Proteomics
- Significant decrease of saturation index in erythrocytes membrane from subjects with non-alcoholic fatty liver disease (NAFLD)
- (2017) Maria Notarnicola et al. Lipids in Health and Disease
- Network analyses identify liver‐specific targets for treating liver diseases
- (2017) Sunjae Lee et al. Molecular Systems Biology
- Revisiting biomarker discovery by plasma proteomics
- (2017) Philipp E Geyer et al. Molecular Systems Biology
- Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics
- (2017) Zijuan Lai et al. NATURE METHODS
- Systems biology guided by XCMS Online metabolomics
- (2017) Tao Huan et al. NATURE METHODS
- HMDB 4.0: the human metabolome database for 2018
- (2017) David S Wishart et al. NUCLEIC ACIDS RESEARCH
- Serum metabolites in non-alcoholic fatty-liver disease development or reversion; a targeted metabolomic approach within the PREDIMED trial
- (2017) Christopher Papandreou et al. Nutrition & Metabolism
- Urinary metabolomics analysis identifies key biomarkers of different stages of nonalcoholic fatty liver disease
- (2017) Shu Dong et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Region and cell-type resolved quantitative proteomic map of the human heart
- (2017) Sophia Doll et al. Nature Communications
- Urinary Metabolomics in Pediatric Obesity and NAFLD Identifies Metabolic Pathways/Metabolites Related to Dietary Habits and Gut-Liver Axis Perturbations
- (2017) Jacopo Troisi et al. Nutrients
- Metabolism dysregulation induces a specific lipid signature of nonalcoholic steatohepatitis in patients
- (2017) Franck Chiappini et al. Scientific Reports
- An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes
- (2017) Dorte B. Bekker-Jensen et al. Cell Systems
- A multi-component classifier for nonalcoholic fatty liver disease (NAFLD) based on genomic, proteomic and phenomic data domains
- (2017) G. Craig Wood et al. Scientific Reports
- Multiomics reveal non-alcoholic fatty liver disease in rats following chronic exposure to an ultra-low dose of Roundup herbicide
- (2017) Robin Mesnage et al. Scientific Reports
- Serum Monounsaturated Triacylglycerol Predicts Steatohepatitis in Patients with Non-alcoholic Fatty Liver Disease and Chronic Hepatitis B
- (2017) Rui-xu Yang et al. Scientific Reports
- Serum aminotransferases in nonalcoholic fatty liver disease are a signature of liver metabolic perturbations at the amino acid and Krebs cycle level1,2
- (2016) Silvia Sookoian et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Clinical and Metabolic Characterization of Lean Caucasian Subjects With Non-alcoholic Fatty Liver
- (2016) Alexandra Feldman et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Serum metabonomics of NAFLD plus T2DM based on liquid chromatography–mass spectrometry
- (2016) Yang Chen et al. CLINICAL BIOCHEMISTRY
- Noninvasive Detection of Nonalcoholic Steatohepatitis Using Clinical Markers and Circulating Levels of Lipids and Metabolites
- (2016) You Zhou et al. Clinical Gastroenterology and Hepatology
- Hepatic ceramides dissociate steatosis and insulin resistance in patients with non-alcoholic fatty liver disease
- (2016) Panu K. Luukkonen et al. JOURNAL OF HEPATOLOGY
- Amino Acid Metabolism is Altered in Adolescents with Nonalcoholic Fatty Liver Disease—An Untargeted, High Resolution Metabolomics Study
- (2016) Ran Jin et al. JOURNAL OF PEDIATRICS
- Mass-spectrometric exploration of proteome structure and function
- (2016) Ruedi Aebersold et al. NATURE
- Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking
- (2016) Mingxun Wang et al. NATURE BIOTECHNOLOGY
- Lipidomics for studying metabolism
- (2016) Xianlin Han Nature Reviews Endocrinology
- The Potential Biomarkers to Identify the Development of Steatosis in Hyperuricemia
- (2016) Yong Tan et al. PLoS One
- Analysis of human plasma metabolites across different liquid chromatography/mass spectrometry platforms: Cross-platform transferable chemical signatures
- (2016) Kelly H. Telu et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- The Size of the Human Proteome: The Width and Depth
- (2016) Elena A. Ponomarenko et al. International Journal of Analytical Chemistry
- The BUME method: a new rapid and simple chloroform-free method for total lipid extraction of animal tissue
- (2016) Lars Löfgren et al. Scientific Reports
- Candidate proteomic biomarkers for non-alcoholic fatty liver disease (steatosis and non-alcoholic steatohepatitis) discovered with mass-spectrometry: a systematic review
- (2015) Anca Lădaru et al. BIOMARKERS
- Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up
- (2015) Mattias Ekstedt et al. HEPATOLOGY
- Multiplexed, Quantitative Workflow for Sensitive Biomarker Discovery in Plasma Yields Novel Candidates for Early Myocardial Injury
- (2015) Hasmik Keshishian et al. MOLECULAR & CELLULAR PROTEOMICS
- MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysis
- (2015) Hiroshi Tsugawa et al. NATURE METHODS
- Methods of integrating data to uncover genotype–phenotype interactions
- (2015) Marylyn D. Ritchie et al. NATURE REVIEWS GENETICS
- 2016 update of the PRIDE database and its related tools
- (2015) Juan Antonio Vizcaíno et al. NUCLEIC ACIDS RESEARCH
- Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes
- (2015) Wasco Wruck et al. Scientific Data
- Liquid chromatography quadrupole time-of-flight mass spectrometry characterization of metabolites guided by the METLIN database
- (2013) Zheng-Jiang Zhu et al. Nature Protocols
- Plasma Proteome Database as a resource for proteomics research: 2014 update
- (2013) Vishalakshi Nanjappa et al. NUCLEIC ACIDS RESEARCH
- Systems Biology Elucidates Common Pathogenic Mechanisms between Nonalcoholic and Alcoholic-Fatty Liver Disease
- (2013) Silvia Sookoian et al. PLoS One
- RNA-Seq and human complex diseases: recent accomplishments and future perspectives
- (2012) Valerio Costa et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- The BUME method: a novel automated chloroform-free 96-well total lipid extraction method for blood plasma
- (2012) Lars Löfgren et al. JOURNAL OF LIPID RESEARCH
- Global metabolic profiling of animal and human tissues via UPLC-MS
- (2012) Elizabeth J Want et al. Nature Protocols
- Increased risk of cardiovascular disease and chronic kidney disease in NAFLD
- (2012) Enzo Bonora et al. Nature Reviews Gastroenterology & Hepatology
- A Comprehensive Untargeted Metabonomic Analysis of Human Steatotic Liver Tissue by RP and HILIC Chromatography Coupled to Mass Spectrometry Reveals Important Metabolic Alterations
- (2011) Juan C. García-Cañaveras et al. JOURNAL OF PROTEOME RESEARCH
- Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
- (2011) Warwick B Dunn et al. Nature Protocols
- The Human Serum Metabolome
- (2011) Nikolaos Psychogios et al. PLoS One
- MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data
- (2010) Tomáš Pluskal et al. BMC BIOINFORMATICS
- Lipidomics: New Tools and Applications
- (2010) Markus R. Wenk CELL
- Lipid map of the mammalian cell
- (2010) G. van Meer et al. JOURNAL OF CELL SCIENCE
- Lipidomics: coming to grips with lipid diversity
- (2010) Andrej Shevchenko et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics
- (2008) Vitali Matyash et al. JOURNAL OF LIPID RESEARCH
- The role of fatty acids in the development and progression of nonalcoholic fatty liver disease
- (2008) Christopher L. Gentile et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
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