A multi-component classifier for nonalcoholic fatty liver disease (NAFLD) based on genomic, proteomic and phenomic data domains

Clinical Presentation and Patient Evaluation in Nonalcoholic Fatty Liver Disease

(2016) Vaishali Patel et al.   Clinics in Liver Disease

Progression and Natural History of Nonalcoholic Fatty Liver Disease in Adults

(2016) Andrea Marengo et al.   Clinics in Liver Disease

Quantitative Imaging Biomarkers of NAFLD

(2016) Sonja Kinner et al.   DIGESTIVE DISEASES AND SCIENCES

Relationships between Genetic Variations of PNPLA3, TM6SF2 and Histological Features of Nonalcoholic Fatty Liver Disease in Japan

(2016) Norio Akuta et al.   Gut and Liver

Noninvasive imaging methods to determine severity of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

(2016) William N. Hannah et al.   HEPATOLOGY

Nonalcoholic fatty liver disease severity is associated with the ratios of total cholesterol and triglycerides to high-density lipoprotein cholesterol

(2016) Kuan-Ta Wu et al.   Journal of Clinical Lipidology

Controlled attenuation parameter for the diagnosis of steatosis in non-alcoholic fatty liver disease

(2016) Victor de Lédinghen et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

The intersection of nonalcoholic fatty liver disease and obesity

(2016) Jennifer A. Woo Baidal et al.   Science Translational Medicine

Respiratory Mucosal Proteome Quantification in Human Influenza Infections

(2016) Tony Marion et al.   PLoS One

Caloric restriction and intermittent fasting alter hepatic lipid droplet proteome and diacylglycerol species and prevent diabetes in NZO mice

(2015) Christian Baumeier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Candidate proteomic biomarkers for non-alcoholic fatty liver disease (steatosis and non-alcoholic steatohepatitis) discovered with mass-spectrometry: a systematic review

(2015) Anca Lădaru et al.   BIOMARKERS

Association Between Endogenous Sex Hormones and Liver Fat in a Multiethnic Study of Atherosclerosis

(2015) Mariana Lazo et al.   Clinical Gastroenterology and Hepatology

Pathobiology of liver fibrosis: a translational success story

(2015) Youngmin A Lee et al.   GUT

Nonalcoholic Fatty Liver Disease

(2015) Mary E. Rinella   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

PNPLA3polymorphisms (rs738409) and non-alcoholic fatty liver disease risk and related phenotypes: a meta-analysis

(2015) Long Zhang et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

I148M variant inPNPLA3reduces central adiposity and metabolic disease risks while increasing nonalcoholic fatty liver disease

(2015) Jin-Ho Park et al.   LIVER INTERNATIONAL

Recommendations for Diagnosis, Referral for Liver Biopsy, and Treatment of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis

(2015) Erin K. Spengler et al.   MAYO CLINIC PROCEEDINGS

Utility of Ultrasound, Transaminases, and Visual Inspection to Assess Nonalcoholic Fatty Liver Disease in Bariatric Surgery Patients

(2015) Anthony Petrick et al.   OBESITY SURGERY

Fatty liver disease: Disparate predictive ability for cardiometabolic risk and all-cause mortality

(2015) Altan Onat   WORLD JOURNAL OF GASTROENTEROLOGY

Association Between Patatin-Like Phospholipase Domain Containing 3 Gene (PNPLA3) Polymorphisms and Nonalcoholic Fatty Liver Disease: A HuGE Review and Meta-Analysis

(2015) Renfan Xu et al.   Scientific Reports

Does Diacylglycerol Accumulation in Fatty Liver Disease Cause Hepatic Insulin Resistance?

(2015) Brian N. Finck et al.   Biomed Research International

Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes

(2015) Wasco Wruck et al.   Scientific Data

Genome-wide analysis of hepatic lipid content in extreme obesity

(2014) Johanna K. DiStefano et al.   ACTA DIABETOLOGICA

Nonalcoholic Fatty Liver Disease in Morbidly Obese Subjects: Correlation Among Histopathologic Findings, Biochemical Features, and Ultrasound Evaluation

(2014) Everton Cazzo et al.   OBESITY SURGERY

Noninvasive biomarkers in non-alcoholic fatty liver disease: Current status and a glimpse of the future

(2014) Emer Fitzpatrick   WORLD JOURNAL OF GASTROENTEROLOGY

Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome

(2014) Hannele Yki-Järvinen   Lancet Diabetes & Endocrinology

Low serum sex hormone-binding globulin is associated with nonalcoholic fatty liver disease in type 2 diabetic patients

(2013) Xiaomin Hua et al.   CLINICAL ENDOCRINOLOGY

Association Between Variants in or Near PNPLA3, GCKR, and PPP1R3B With Ultrasound-Defined Steatosis Based on Data From the Third National Health and Nutrition Examination Survey

(2013) Ruben Hernaez et al.   Clinical Gastroenterology and Hepatology

Prothrombotic factors in histologically proven nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

(2013) An Verrijken et al.   HEPATOLOGY

Genetic Variation at NCAN Locus Is Associated with Inflammation and Fibrosis in Non-Alcoholic Fatty Liver Disease in Morbid Obesity

(2013) Alexis Gorden et al.   HUMAN HEREDITY

Non-alcoholic fatty liver disease: Factors associated with its presence and onset

(2013) Teruki Miyake et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Identification of candidate biomarkers for hepatocellular carcinoma in plasma of HCV-infected cirrhotic patients by 2-D DIGE

(2013) Gustavo Ferrín et al.   LIVER INTERNATIONAL

A gene variant ofPNPLA3, but not ofAPOC3, is associated with histological parameters of NAFLD in an obese population

(2013) A. Verrijken et al.   Obesity

An electronic health record-enabled obesity database

(2012) G Craig Wood et al.   BMC Medical Informatics and Decision Making

The Relevance of Liver Histology to Predicting Clinically Meaningful Outcomes in Nonalcoholic Steatohepatitis

(2012) Mangesh R. Pagadala et al.   Clinics in Liver Disease

The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association

(2012) Naga Chalasani et al.   HEPATOLOGY

N-Terminal Region of Gelsolin Induces Apoptosis of Activated Hepatic Stellate Cells by a Caspase-Dependent Mechanism

(2012) Budhaditya Mazumdar et al.   PLoS One

Changes in the Prevalence of the Most Common Causes of Chronic Liver Diseases in the United States From 1988 to 2008

(2011) Zobair M. Younossi et al.   Clinical Gastroenterology and Hepatology

Serum sex hormone-binding globulin levels are independently associated with nonalcoholic fatty liver disease in people with type 2 diabetes

(2011) Jang Yel Shin et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Usefulness of a novel serum proteome-derived index FI-PRO (fibrosis-protein) in the prediction of fibrosis in chronic hepatitis C

(2011) Kin Jip Cheung et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Pathologic criteria for nonalcoholic steatohepatitis: Interprotocol agreement and ability to predict liver-related mortality

(2011) Zobair M. Younossi et al.   HEPATOLOGY

Advances in human proteomics at high scale with the SOMAscan proteomics platform

(2011) Larry Gold et al.   New Biotechnology

Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery

(2011) Larry Gold et al.   PLoS One

From SOMAmer-Based Biomarker Discovery to Diagnostic and Clinical Applications: A SOMAmer-Based, Streamlined Multiplex Proteomic Assay

(2011) Stephan Kraemer et al.   PLoS One

Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits

(2011) Elizabeth K. Speliotes et al.   PLoS Genetics

Reduced Mortality Rates Following Elective Percutaneous Liver Biopsies

(2010) Joe West et al.   GASTROENTEROLOGY

PNPLA3variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease

(2010) Elizabeth K. Speliotes et al.   HEPATOLOGY

Stability selection

(2010) Nicolai Meinshausen et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

(2009) A. Kotronen et al.   DIABETOLOGIA

Prediction of Non-Alcoholic Fatty Liver Disease and Liver Fat Using Metabolic and Genetic Factors

(2009) Anna Kotronen et al.   GASTROENTEROLOGY

The stability of the circulating human proteome to variations in sample collection and handling procedures measured with an aptamer-based proteomics array

(2009) Rachel Ostroff et al.   Journal of Proteomics

Sex Hormone–Binding Globulin and Risk of Type 2 Diabetes

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

Association of Morbid Obesity With FTO and INSIG2 Allelic Variants

(2008) Xin Chu   ARCHIVES OF SURGERY

Long-Term Follow-Up of Patients With Nonalcoholic Fatty Liver

(2008) Nila Rafiq et al.   Clinical Gastroenterology and Hepatology

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS