Neurogranin and Neuronal Pentraxin Receptor as Synaptic Dysfunction Biomarkers in Alzheimer’s Disease

Increased excitatory to inhibitory synaptic ratio in parietal cortex samples from individuals with Alzheimer’s disease

(2021) Julie C. Lauterborn et al.   Nature Communications

Planar cell polarity signaling components are a direct target of β-amyloid–associated degeneration of glutamatergic synapses

(2021) Bo Feng et al.   Science Advances

Contribution of CSF biomarkers to early‐onset Alzheimer's disease and frontotemporal dementia neuroimaging signatures

(2020) Neus Falgàs et al.   HUMAN BRAIN MAPPING

Neurogranin Regulates Metaplasticity

(2020) Ling Zhong et al.   Frontiers in Molecular Neuroscience

In vivo measurement of widespread synaptic loss in Alzheimer's disease with SV2A PET

(2020) Adam P. Mecca et al.   Alzheimers & Dementia

New fluid biomarkers tracking non-amyloid-β and non-tau pathology in Alzheimer’s disease

(2020) Sun Ah Park et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Cerebrospinal fluid neuronal pentraxin receptor as a biomarker of long-term progression of Alzheimer's disease: a 24-month follow-up study

(2020) Bryant Lim et al.   NEUROBIOLOGY OF AGING

Decreased cerebrospinal fluid neuronal pentraxin receptor is associated with PET-Aβ load and cerebrospinal fluid Aβ in a pilot study of Alzheimer’s disease

(2020) Bryant Lim et al.   NEUROSCIENCE LETTERS

Calmodulin Binding Proteins and Alzheimer’s Disease: Biomarkers, Regulatory Enzymes and Receptors That Are Regulated by Calmodulin

(2020) Danton H. O’Day   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Changes in synaptic proteins precede neurodegeneration markers in preclinical Alzheimer’s disease cerebrospinal fluid

(2019) Alberto Lleó et al.   MOLECULAR & CELLULAR PROTEOMICS

The Role of NMDA Receptors in Alzheimer’s Disease

(2019) Jinping Liu et al.   Frontiers in Neuroscience

CSF neurogranin as a neuronal damage marker in CJD: a comparative study with AD

(2019) Kaj Blennow et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Synaptic and memory dysfunction induced by tau oligomers is rescued by up-regulation of the nitric oxide cascade

(2019) Erica Acquarone et al.   Molecular Neurodegeneration

Targeting Synaptic Plasticity in Experimental Models of Alzheimer’s Disease

(2019) Dalila Mango et al.   Frontiers in Pharmacology

The neuropathological diagnosis of Alzheimer’s disease

(2019) Michael A. DeTure et al.   Molecular Neurodegeneration

Targeting the Synapse in Alzheimer’s Disease

(2019) Johanna Jackson et al.   Frontiers in Neuroscience

CSF synaptic protein concentrations are raised in those with atypical Alzheimer’s disease but not frontotemporal dementia

(2019) Mica T. M. Clarke et al.   Alzheimers Research & Therapy

The Past and the Future of Alzheimer’s Disease Fluid Biomarkers

(2018) Kaj Blennow et al.   JOURNAL OF ALZHEIMERS DISEASE

Neurodegeneration, synaptic dysfunction, and gliosis are phenotypic of Alzheimer dementia

(2018) Andrew P. Merluzzi et al.   NEUROLOGY

Dendritic Tau in Alzheimer’s Disease

(2018) Arne Ittner et al.   NEURON

Synaptic plasticity modulation by circulating peptides and metaplasticity: Involvement in Alzheimer’s disease

(2018) Stéphane Peineau et al.   PHARMACOLOGICAL RESEARCH

The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer’s disease

(2018) Hlin Kvartsberg et al.   ACTA NEUROPATHOLOGICA

A Novel ELISA for the Measurement of Cerebrospinal Fluid SNAP-25 in Patients with Alzheimer’s Disease

(2018) Annika Öhrfelt et al.   NEUROSCIENCE

The Regulation of AMPA Receptor Endocytosis by Dynamic Protein-Protein Interactions

(2018) Jonathan G. Hanley   Frontiers in Cellular Neuroscience

Association between cerebrospinal fluid and plasma neurodegeneration biomarkers with brain atrophy in Alzheimer's disease

(2017) Joana B. Pereira et al.   NEUROBIOLOGY OF AGING

Amyloid-β as a Modulator of Synaptic Plasticity

(2017) Mordhwaj S. Parihar et al.   JOURNAL OF ALZHEIMERS DISEASE

Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia

(2016) Erika Bereczki et al.   Alzheimers & Dementia

Cerebrospinal fluid tau, neurogranin, and neurofilament light in Alzheimer's disease

(2016) Niklas Mattsson et al.   EMBO Molecular Medicine

Neurogranin restores amyloid β-mediated synaptic transmission and long-term potentiation deficits

(2016) Kanwardeep Singh Kaleka et al.   EXPERIMENTAL NEUROLOGY

Increased neurogranin concentrations in cerebrospinal fluid of Alzheimer’s disease and in mild cognitive impairment due to AD

(2016) Cristina Sanfilippo et al.   JOURNAL OF NEURAL TRANSMISSION

Presynaptic Neuronal Pentraxin Receptor Organizes Excitatory and Inhibitory Synapses

(2016) Sung-Jin Lee et al.   JOURNAL OF NEUROSCIENCE

Increased CSF neurogranin concentration is specific to Alzheimer disease

(2016) Henrietta Wellington et al.   NEUROLOGY

Diagnostic and Prognostic Utility of the Synaptic Marker Neurogranin in Alzheimer Disease

(2016) Rawan Tarawneh et al.   JAMA Neurology

Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease

(2015) Hlin Kvartsberg et al.   Alzheimers & Dementia

C-terminal neurogranin is increased in cerebrospinal fluid but unchanged in plasma in Alzheimer's disease

(2015) Ann De Vos et al.   Alzheimers & Dementia

Cerebrospinal fluid neurogranin: relation to cognition and neurodegeneration in Alzheimer’s disease

(2015) Erik Portelius et al.   BRAIN

Pentraxins Coordinate Excitatory Synapse Maturation and Circuit Integration of Parvalbumin Interneurons

(2015) Kenneth A. Pelkey et al.   NEURON

Neurogranin regulates CaM dynamics at dendritic spines

(2015) Amber Petersen et al.   Scientific Reports

Neurogranin and YKL-40: independent markers of synaptic degeneration and neuroinflammation in Alzheimer’s disease

(2015) Konstantin Hellwig et al.   Alzheimers Research & Therapy

Cerebrospinal Fluid Markers of Neurodegeneration and Rates of Brain Atrophy in Early Alzheimer Disease

(2015) Rawan Tarawneh et al.   JAMA Neurology

Neurogranin Targets Calmodulin and Lowers the Threshold for the Induction of Long-Term Potentiation

(2012) Ling Zhong et al.   PLoS One

NMDA Receptor-Dependent Long-Term Potentiation and Long-Term Depression (LTP/LTD)

(2012) C. Luscher et al.   Cold Spring Harbor Perspectives in Biology

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant

(2011) A. Sydow et al.   JOURNAL OF NEUROSCIENCE

Neuropathologically defined subtypes of Alzheimer's disease with distinct clinical characteristics: a retrospective study

(2011) Melissa E Murray et al.   LANCET NEUROLOGY

Early onset amyloid lesions lead to severe neuritic abnormalities and local, but not global neuron loss in APPPS1 transgenic mice

(2010) Niels J. Rupp et al.   NEUROBIOLOGY OF AGING

Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

(2010) Brian R. Hoover et al.   NEURON

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

(2010) S. F. Traynelis et al.   PHARMACOLOGICAL REVIEWS

Synaptic Plasticity in the Hippocampus of a APP/PS1 Mouse Model of Alzheimer's Disease Is Impaired in Old but Not Young Mice

(2010) Simon Gengler et al.   PLoS One

Long-term potentiation: two pathways meet at neurogranin

(2009) Yasunori Hayashi   EMBO JOURNAL

Neurochemical dementia diagnostics: a simple algorithm for interpretation of the CSF biomarkers

(2009) Piotr Lewczuk et al.   JOURNAL OF NEURAL TRANSMISSION