Increased excitatory to inhibitory synaptic ratio in parietal cortex samples from individuals with Alzheimer’s disease

Whole-Neuron Synaptic Mapping Reveals Spatially Precise Excitatory/Inhibitory Balance Limiting Dendritic and Somatic Spiking

(2020) Daniel Maxim Iascone et al.   NEURON

Preservation of global synaptic excitatory to inhibitory ratio during long postmortem intervals

(2020) Pietro Scaduto et al.   Scientific Reports

Functional impairment of cortical AMPA receptors in schizophrenia

(2020) Tommaso Zeppillo et al.   SCHIZOPHRENIA RESEARCH

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

Synaptic actin stabilization protein loss in Down syndrome and Alzheimer disease

(2019) Julie C. Lauterborn et al.   BRAIN PATHOLOGY

What Happens with the Circuit in Alzheimer's Disease in Mice and Humans?

(2018) Benedikt Zott et al.   Annual Review of Neuroscience

Imbalance between firing homeostasis and synaptic plasticity drives early-phase Alzheimer’s disease

(2018) Boaz Styr et al.   NATURE NEUROSCIENCE

Dendritic Tau in Alzheimer’s Disease

(2018) Arne Ittner et al.   NEURON

Epileptic seizures in autosomal dominant forms of Alzheimer’s disease

(2018) Francesca Cortini et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

(2018) David M. Howard et al.   Nature Communications

Synaptic E-I Balance Underlies Efficient Neural Coding

(2018) Shanglin Zhou et al.   Frontiers in Neuroscience

Phosphorylation of different tau sites during progression of Alzheimer’s disease

(2018) Joerg Neddens et al.   Acta Neuropathologica Communications

Microtransplantation of human brain receptors into oocytes to tackle key questions in drug discovery

(2018) Ruud Zwart et al.   DRUG DISCOVERY TODAY

Towards a Better Understanding of GABAergic Remodeling in Alzheimer’s Disease

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Therapeutics of Neurotransmitters in Alzheimer’s Disease

(2017) Ramesh Kandimalla et al.   JOURNAL OF ALZHEIMERS DISEASE

Reduced Expression of the Inhibitory Synapse Scaffolding Protein Gephyrin in Alzheimer's Disease

(2017) Smriti Agarwal et al.   JOURNAL OF ALZHEIMERS DISEASE

Near infrared light decreases synaptic vulnerability to amyloid beta oligomers

(2017) Michele M. Comerota et al.   Scientific Reports

Cognitive Profiles on the Severe Impairment Battery Are Similar in Alzheimer Disease and Down Syndrome With Dementia

(2016) Malcolm B. Dick et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Default Mode Network Functional Connectivity in Early and Late Mild Cognitive Impairment

(2016) Eek-Sung Lee et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Reconstitution of synaptic Ion channels from rodent and human brain inXenopusoocytes: a biochemical and electrophysiological characterization

(2016) Francesca Mazzo et al.   JOURNAL OF NEUROCHEMISTRY

Gene‐specific correlation of RNA and protein levels in human cells and tissues

(2016) Fredrik Edfors et al.   Molecular Systems Biology

Synaptic scaling rule preserves excitatory–inhibitory balance and salient neuronal network dynamics

(2016) Jérémie Barral et al.   NATURE NEUROSCIENCE

Network abnormalities and interneuron dysfunction in Alzheimer disease

(2016) Jorge J. Palop et al.   NATURE REVIEWS NEUROSCIENCE

Plasticity of Cortical Excitatory-Inhibitory Balance

(2015) Robert C. Froemke   Annual Review of Neuroscience

Equalizing excitation–inhibition ratios across visual cortical neurons

(2014) Mingshan Xue et al.   NATURE

Age-related decreased inhibitory vs. excitatory gene expression in the adult autistic brain

(2014) Louie N. van de Lagemaat et al.   Frontiers in Neuroscience

Abnormal Gephyrin Immunoreactivity Associated With Alzheimer Disease Pathologic Changes

(2013) Chadwick M. Hales et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model

(2012) Laure Verret et al.   CELL

Interaction of Endogenous Tau Protein with Synaptic Proteins Is Regulated byN-Methyl-d-aspartate Receptor-dependent Tau Phosphorylation

(2012) Siddhartha Mondragón-Rodríguez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LTP Induction Translocates Cortactin at Distant Synapses in Wild-Type But Not Fmr1 Knock-Out Mice

(2012) R. R. Seese et al.   JOURNAL OF NEUROSCIENCE

Absence of amyloid β oligomers at the postsynapse and regulated synaptic Zn2+ in cognitively intact aged individuals with Alzheimer’s disease neuropathology

(2012) Nicole L Bjorklund et al.   Molecular Neurodegeneration

Loss of functional GABAA receptors in the Alzheimer diseased brain

(2012) A. Limon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurotransmitter receptors and cognitive dysfunction in Alzheimer's disease and Parkinson's disease

(2012) Yunqi Xu et al.   PROGRESS IN NEUROBIOLOGY

Alzheimer’s disease is not “brain aging”: neuropathological, genetic, and epidemiological human studies

(2011) Peter T. Nelson et al.   ACTA NEUROPATHOLOGICA

A perfect storm: Converging paths of epilepsy and Alzheimer’s dementia intersect in the hippocampal formation

(2011) Jeffrey Noebels   EPILEPSIA

Not All Desensitizations Are Created Equal: Physiological Evidence That AMPA Receptor Desensitization Differs for Kainate and Glutamate

(2011) Y. Levchenko-Lambert et al.   JOURNAL OF NEUROSCIENCE

Homeostatic Synaptic Plasticity: Local and Global Mechanisms for Stabilizing Neuronal Function

(2011) G. Turrigiano   Cold Spring Harbor Perspectives in Biology

Physiological Activation of Synaptic Rac>PAK (p-21 Activated Kinase) Signaling Is Defective in a Mouse Model of Fragile X Syndrome

(2010) L. Y. Chen et al.   JOURNAL OF NEUROSCIENCE

Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

(2010) Brian R. Hoover et al.   NEURON

Different Rho GTPase–dependent signaling pathways initiate sequential steps in the consolidation of long-term potentiation

(2009) Christopher S. Rex et al.   JOURNAL OF CELL BIOLOGY

Microtransplantation of ligand-gated receptor-channels from fresh or frozen nervous tissue into Xenopus oocytes: A potent tool for expanding functional information

(2009) F. Eusebi et al.   PROGRESS IN NEUROBIOLOGY

Diminished perisomatic GABAergic terminals on cortical neurons adjacent to amyloid plaques

(2009) Virginia Garcia-Marin   Frontiers in Neuroanatomy

The Brain's Default Network

(2008) Randy L. Buckner et al.   Annals of the New York Academy of Sciences

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Functional connectivity of default mode network components: Correlation, anticorrelation, and causality

(2008) Lucina Q. Uddin et al.   HUMAN BRAIN MAPPING

Instantaneous correlation of excitation and inhibition during ongoing and sensory-evoked activities

(2008) Michael Okun et al.   NATURE NEUROSCIENCE

Microtransplantation of neurotransmitter receptors from postmortem autistic brains to Xenopus oocytes

(2008) A. Limon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroprotective effects of atypical D1receptor agonist SKF83959 are mediated via D1receptor-dependent inhibition of glycogen synthase kinase-3β and a receptor-independent anti-oxidative action

(2007) Yang Yu et al.   JOURNAL OF NEUROCHEMISTRY