Multi-stage metabolomics and genetic analyses identified metabolite biomarkers of metabolic syndrome and their genetic determinants

Body roundness index is a superior indicator to associate with the cardio‐metabolic risk: evidence from a cross‐sectional study with 17,000 Eastern-China adults

(2021) Jinjian Xu et al.   BMC Cardiovascular Disorders

Genetic Determinants of Clustering of Cardiometabolic Risk Factors in U.K. Biobank

(2020) Lars Lind   Metabolic Syndrome and Related Disorders

Genome-wide association study of metabolic syndrome in Korean populations

(2020) Seung-Won Oh et al.   PLoS One

Oxidized LDL induces procoagulant profiles by increasing lysophosphatidylcholine levels, lysophosphatidylethanolamine levels, and Lp-PLA2 activity in borderline hypercholesterolemia

(2020) Minjoo Kim et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Detection of Early Disease Risk Factors Associated with Metabolic Syndrome: A New Era with the NMR Metabolomics Assessment

(2020) Julia Hernandez-Baixauli et al.   Nutrients

Liquid chromatography-mass spectrometry untargeted metabolomics reveals increased levels of tryptophan indole metabolites in urine of metabolic syndrome patients

(2020) Moises Guerrero Esperanza et al.   EUROPEAN JOURNAL OF MASS SPECTROMETRY

Plasma metabolomics are associated with metabolic syndrome: A targeted approach

(2020) Antonio Augusto Ferreira Carioca et al.   NUTRITION

Metabolomic and lipidomic assessment of the metabolic syndrome in Dutch middle-aged individuals reveals novel biological signatures separating health and disease

(2019) Izabella Surowiec et al.   Metabolomics

An Updated Review of Lysophosphatidylcholine Metabolism in Human Diseases

(2019) Shi-Hui Law et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tyrosine and Glutamine–leucine are Metabolic Markers of Early-stage Colorectal Cancers

(2019) Jiankang Li et al.   GASTROENTEROLOGY

Metabolically unhealthy overweight individuals have high lysophosphatide levels, phospholipase activity, and oxidative stress

(2019) Minjoo Kim et al.   CLINICAL NUTRITION

Are we close to defining a metabolomic signature of human obesity? A systematic review of metabolomics studies

(2019) Oscar Daniel Rangel-Huerta et al.   Metabolomics

High-Coverage Targeted Lipidomics Reveals Novel Serum Lipid Predictors and Lipid Pathway Dysregulation Antecedent to Type 2 Diabetes Onset in Normoglycemic Chinese Adults

(2019) Jieli Lu et al.   DIABETES CARE

Genome-Wide Association Study of the Metabolic Syndrome in UK Biobank

(2019) Lars Lind   Metabolic Syndrome and Related Disorders

Discovery of metabolite profiles of metabolic syndrome using untargeted and targeted LC–MS based lipidomics approach

(2019) Li-li Gong et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Lipidomic profiling identifies signatures of metabolic risk

(2019) Xiaoyan Yin et al.   EBioMedicine

Study of the metabolomics characteristics of patients with metabolic syndrome based on liquid chromatography quadrupole time-of-flight mass spectrometry

(2018) Ning Wu et al.   ANNALES D ENDOCRINOLOGIE

The Global Epidemic of the Metabolic Syndrome

(2018) Mohammad G. Saklayen   CURRENT HYPERTENSION REPORTS

Amino acid levels in nascent metabolic syndrome: A contributor to the pro-inflammatory burden

(2018) Priya Reddy et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Dysregulation of Tryptophan Catabolism in Metabolic Syndrome

(2018) Neila Hiraishi Mallmann et al.   Metabolic Syndrome and Related Disorders

Changes in lysophospholipids and liver status after weight loss: the RESMENA study

(2018) Irene Cantero et al.   Nutrition & Metabolism

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

(2018) Evangelos Evangelou et al.   NATURE GENETICS

Metabolomic analysis of obesity, metabolic syndrome, and type 2 diabetes: amino acid and acylcarnitine levels change along a spectrum of metabolic wellness

(2018) Diane M. Libert et al.   PeerJ

Exploratory metabolomics of nascent metabolic syndrome

(2018) Kyumin Shim et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Serum metabolites and risk of myocardial infarction and ischemic stroke: a targeted metabolomic approach in two German prospective cohorts

(2017) Anna Floegel et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study

(2017) Yimin Zhu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites

(2017) Tao Long et al.   NATURE GENETICS

n-3 Polyunsaturated Fatty Acids and Metabolic Syndrome Risk: A Meta-Analysis

(2017) Xiao-fei Guo et al.   Nutrients

Lipidomic profiling reveals distinct differences in plasma lipid composition in healthy, prediabetic, and type 2 diabetic individuals

(2017) Huanzi Zhong et al.   GigaScience

What Have Metabolomics Approaches Taught Us About Type 2 Diabetes?

(2016) Alba Gonzalez-Franquesa et al.   Current Diabetes Reports

Non-targeted metabolomics combined with genetic analyses identifies bile acid synthesis and phospholipid metabolism as being associated with incident type 2 diabetes

(2016) Tove Fall et al.   DIABETOLOGIA

Fast and accurate long-range phasing in a UK Biobank cohort

(2016) Po-Ru Loh et al.   NATURE GENETICS

Metabolomics: beyond biomarkers and towards mechanisms

(2016) Caroline H. Johnson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease

(2016) Jaana A. Hartiala et al.   Nature Communications

Docosapentaenoic acid and docosahexaenoic acid are positively associated with insulin sensitivity in rats fed high-fat and high-fructose diets

(2016) Jiung-Pang Huang et al.   Journal of Diabetes

Association between n-3 polyunsaturated fatty acids in erythrocytes and metabolic syndrome in Chinese men and women

(2015) Xiao-wei Dai et al.   EUROPEAN JOURNAL OF NUTRITION

Plasma acylcarnitines inadequately reflect tissue acylcarnitine metabolism

(2014) Marieke G. Schooneman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Adipose tissue n-3 fatty acids and metabolic syndrome

(2014) E Cespedes et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Serum metabolic profiles in overweight and obese women with and without metabolic syndrome

(2014) Petri K Wiklund et al.   Diabetology & Metabolic Syndrome

Genome-Wide Association Study of Metabolic Traits Reveals Novel Gene-Metabolite-Disease Links

(2014) Rico Rueedi et al.   PLoS Genetics

A Genome-wide Association Study of the Human Metabolome in a Community-Based Cohort

(2013) Eugene P. Rhee et al.   Cell Metabolism

Use of Systems Biology Approaches to Analysis of Genome-Wide Association Studies of Myocardial Infarction and Blood Cholesterol in the Nurses' Health Study and Health Professionals’ Follow-Up Study

(2013) Dermot Reilly et al.   PLoS One

Novel bioactive glycerol-based lysophospholipids: New data – New insight into their function

(2012) Anna Grzelczyk et al.   BIOCHIMIE

Metabolomic Profiling for the Identification of Novel Biomarkers and Mechanisms Related to Common Cardiovascular Diseases

(2012) Svati H. Shah et al.   CIRCULATION

Novel biomarkers for pre-diabetes identified by metabolomics

(2012) Rui Wang-Sattler et al.   Molecular Systems Biology

Dense Genotyping of Candidate Gene Loci Identifies Variants Associated With High-Density Lipoprotein Cholesterol

(2011) Andrew C. Edmondson et al.   Circulation-Cardiovascular Genetics

Genetic Loci Associated with Plasma Phospholipid n-3 Fatty Acids: A Meta-Analysis of Genome-Wide Association Studies from the CHARGE Consortium

(2011) Rozenn N. Lemaitre et al.   PLoS Genetics

Metabolic Profiling of Plasma in Overweight/Obese and Lean Men using Ultra Performance Liquid Chromatography and Q-TOF Mass Spectrometry (UPLC−Q-TOF MS)

(2010) Ji Young Kim et al.   JOURNAL OF PROTEOME RESEARCH

Plasma phospholipids n-3 polyunsaturated fatty acid is associated with metabolic syndrome

(2010) Tao Huang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Increased Levels of Plasma Acylcarnitines in Obesity and Type 2 Diabetes and Identification of a Marker of Glucolipotoxicity

(2010) Stephanie J. Mihalik et al.   Obesity

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

Relationships Between Circulating Metabolic Intermediates and Insulin Action in Overweight to Obese, Inactive Men and Women

(2009) K. M. Huffman et al.   DIABETES CARE