Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins

Viral G Protein–Coupled Receptors: Attractive Targets for Herpesvirus-Associated Diseases

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Structural basis for the constitutive activity and immunomodulatory properties of the Epstein-Barr virus-encoded G protein-coupled receptor BILF1

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Structure of the neurotensin receptor 1 in complex with β-arrestin 1

(2020) Weijiao Huang et al.   NATURE

Structural basis of CXC chemokine receptor 2 activation and signalling

(2020) Kaiwen Liu et al.   NATURE

Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20

(2020) David Jonathan Wasilko et al.   Nature Communications

Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor

(2020) Kuglae Kim et al.   CELL

Emerging roles of cytomegalovirus-encoded G protein-coupled receptors during lytic and latent infection

(2019) Theresa Frank et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

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(2019) Yang Du et al.   CELL

Conformational transitions of a neurotensin receptor 1–Gi1 complex

(2019) Hideaki E. Kato et al.   NATURE

Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix

(2019) Dorothee Liebschner et al.   Acta Crystallographica Section D-Structural Biology

DeepRes: a new deep-learning- and aspect-based local resolution method for electron-microscopy maps

(2019) Erney Ramírez-Aportela et al.   IUCrJ

Common activation mechanism of class A GPCRs

(2019) Qingtong Zhou et al.   eLife

Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy

(2018) Timothy F Miles et al.   eLife

GPU-Accelerated Molecular Dynamics and Free Energy Methods in Amber18: Performance Enhancements and New Features

(2018) Tai-Sung Lee et al.   Journal of Chemical Information and Modeling

US28: HCMV’s Swiss Army Knife

(2018) Benjamin Krishna et al.   Viruses-Basel

Development of an antibody fragment that stabilizes GPCR/G-protein complexes

(2018) Shoji Maeda et al.   Nature Communications

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

Evolution of the ability to modulate host chemokine networks via gene duplication in human cytomegalovirus (HCMV)

(2017) Jessica A. Scarborough et al.   INFECTION GENETICS AND EVOLUTION

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(2017) Tilman Flock et al.   NATURE

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

Addressing preferred specimen orientation in single-particle cryo-EM through tilting

(2017) Yong Zi Tan et al.   NATURE METHODS

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

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Attenuation of chemokine receptor function and surface expression as an immunomodulatory strategy employed by human cytomegalovirus is linked to vGPCR US28

(2016) Theresa Frank et al.   Cell Communication and Signaling

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

CHARMM36m: an improved force field for folded and intrinsically disordered proteins

(2016) Jing Huang et al.   NATURE METHODS

Long-Time-Step Molecular Dynamics through Hydrogen Mass Repartitioning

(2015) Chad W. Hopkins et al.   Journal of Chemical Theory and Computation

Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor

(2015) J. S. Burg et al.   SCIENCE

Generic GPCR residue numbers – aligning topology maps while minding the gaps

(2015) Vignir Isberg et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Chemokines and Chemokine Receptors: Positioning Cells for Host Defense and Immunity

(2014) Jason W. Griffith et al.   Annual Review of Immunology

Insights into the Role of Asp792.50 in β2 Adrenergic Receptor Activation from Molecular Dynamics Simulations

(2014) Anirudh Ranganathan et al.   BIOCHEMISTRY

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(2014) Paul Griffiths et al.   JOURNAL OF PATHOLOGY

PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data

(2013) Daniel R. Roe et al.   Journal of Chemical Theory and Computation

Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 2. Explicit Solvent Particle Mesh Ewald

(2013) Romelia Salomon-Ferrer et al.   Journal of Chemical Theory and Computation

Molecular Mechanisms Deployed by Virally Encoded G Protein–Coupled Receptors in Human Diseases

(2011) Silvia Montaner et al.   Annual Review of Pharmacology and Toxicology

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(2011) Jatta Huotari et al.   EMBO JOURNAL

PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKaPredictions

(2011) Mats H. M. Olsson et al.   Journal of Chemical Theory and Computation

Review of cytomegalovirus seroprevalence and demographic characteristics associated with infection

(2010) Michael J. Cannon et al.   REVIEWS IN MEDICAL VIROLOGY