Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy

Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV

(2017) Yi Zheng et al.   IMMUNITY

Structural Analysis of Chemokine Receptor–Ligand Interactions

(2017) Marta Arimont et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure-inspired design of β-arrestin-biased ligands for aminergic GPCRs

(2017) John D McCorvy et al.   Nature Chemical Biology

Structural basis for chemokine recognition by a G protein–coupled receptor and implications for receptor activation

(2017) Joshua J. Ziarek et al.   Science Signaling

Structural basis for chemokine recognition by a G protein–coupled receptor and implications for receptor activation

(2017) Joshua J. Ziarek et al.   Science Signaling

Structure-based discovery of novel US28 small molecule ligands with different modes of action

(2016) Michael Lückmann et al.   Chemical Biology & Drug Design

GPCR Dynamics: Structures in Motion

(2016) Naomi R. Latorraca et al.   CHEMICAL REVIEWS

Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation

(2016) Dean P. Staus et al.   NATURE

Activation mechanism of endothelin ETB receptor by endothelin-1

(2016) Wataru Shihoya et al.   NATURE

Signal transmission through the CXC chemokine receptor 4 (CXCR4) transmembrane helices

(2016) Melanie P. Wescott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural insights into µ-opioid receptor activation

(2015) Weijiao Huang et al.   NATURE

Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor

(2015) J. S. Burg et al.   SCIENCE

The Structure of a CXCR4:Chemokine Complex

(2015) Tracy Marie Handel   Frontiers in Immunology

Allosteric modulation of the G protein-coupled US28 receptor of human cytomegalovirus: Are the small-weight inverse agonist of US28 ‘camouflaged’ agonists?

(2014) Nuska Tschammer   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Deconstructing the Peptide-MHC Specificity of T Cell Recognition

(2014) Michael E. Birnbaum et al.   CELL

Interaction of Chemokines with their Receptors – From Initial Chemokine Binding to Receptor Activating Steps

(2014) Stefanie Thiele et al.   CURRENT MEDICINAL CHEMISTRY

Biased and G Protein-Independent Signaling of Chemokine Receptors

(2014) Anne Steen et al.   Frontiers in Immunology

Human cytomegalovirus chemokine receptor US28 induces migration of cells on a CX3CL1-presenting surface

(2013) G. M. Hjorto et al.   JOURNAL OF GENERAL VIROLOGY

Activation and allosteric modulation of a muscarinic acetylcholine receptor

(2013) Andrew C. Kruse et al.   NATURE

Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody

(2013) Aaron M. Ring et al.   NATURE

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

Use of knowledge-based restraints inphenix.refineto improve macromolecular refinement at low resolution

(2012) Jeffrey J. Headd et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Graphical tools for macromolecular crystallography inPHENIX

(2012) Nathaniel Echols et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists

(2010) B. Wu et al.   SCIENCE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The structure and function of G-protein-coupled receptors

(2009) Daniel M. Rosenbaum et al.   NATURE