Cytokine-scavenging nanodecoys reconstruct osteoclast/osteoblast balance toward the treatment of postmenopausal osteoporosis

Extracellular Vesicles from Child Gut Microbiota Enter into Bone to Preserve Bone Mass and Strength

(2021) Jiang‐Hua Liu et al.   Advanced Science

Inflammation‐Instructed Hierarchical Delivery of IL‐4/miR‐21 Orchestrates Osteoimmune Microenvironment toward the Treatment of Rheumatoid Arthritis

(2021) Yekun Deng et al.   ADVANCED FUNCTIONAL MATERIALS

Cell-mimicking nanodecoys neutralize SARS-CoV-2 and mitigate lung injury in a non-human primate model of COVID-19

(2021) Zhenhua Li et al.   Nature Nanotechnology

Cell-Membrane-Mimicking Nanodecoys against Infectious Diseases

(2020) Lang Rao et al.   ACS Nano

A broader strategy for osteoporosis interventions

(2020) Ian R. Reid   Nature Reviews Endocrinology

Decoy nanoparticles protect against COVID-19 by concurrently adsorbing viruses and inflammatory cytokines

(2020) Lang Rao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Stem Cell-Platelet Hybrid Membrane-Coated Magnetic Nanoparticles for Enhanced Photothermal Therapy of Head and Neck Squamous Cell Carcinoma

(2019) Lin-Lin Bu et al.   ADVANCED FUNCTIONAL MATERIALS

TG-interacting factor 1 (Tgif1)-deficiency attenuates bone remodeling and blunts the anabolic response to parathyroid hormone

(2019) Hiroaki Saito et al.   Nature Communications

TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis

(2019) Jinbo Li et al.   Nature Communications

Cell Membrane Coating Nanotechnology

(2018) Ronnie H. Fang et al.   ADVANCED MATERIALS

IL-6 trans -signalling mediates trabecular, but not cortical, bone loss after ovariectomy

(2018) Leah Lazzaro et al.   BONE

Ovariectomy-induced bone loss in TNFα and IL6 gene knockout mice is regulated by different mechanisms

(2018) Siyi Zhu et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Updating osteoimmunology: regulation of bone cells by innate and adaptive immunity

(2018) Matthew C. Walsh et al.   Nature Reviews Rheumatology

The role of osteoprotegerin in the crosstalk between vessels and bone: Its potential utility as a marker of cardiometabolic diseases

(2018) Luc Rochette et al.   PHARMACOLOGY & THERAPEUTICS

Neutrophil membrane-coated nanoparticles inhibit synovial inflammation and alleviate joint damage in inflammatory arthritis

(2018) Qiangzhe Zhang et al.   Nature Nanotechnology

Cationic nanoparticle as an inhibitor of cell-free DNA-induced inflammation

(2018) Huiyi Liang et al.   Nature Communications

Macrophage-like nanoparticles concurrently absorbing endotoxins and proinflammatory cytokines for sepsis management

(2017) Soracha Thamphiwatana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts

(2017) Zhan Xu et al.   Nature Communications

The HIV co-receptor CCR5 regulates osteoclast function

(2017) Ji-Won Lee et al.   Nature Communications

Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway

(2017) Mengrui Wu et al.   Nature Communications

TNF-α inhibits SATB2 expression and osteoblast differentiation through NF-κB and MAPK pathways

(2017) Chijian Zuo et al.   Oncotarget

Two-year clinical outcome of denosumab treatment alone and in combination with teriparatide in Japanese treatment-naive postmenopausal osteoporotic women

(2017) Yukio Nakamura et al.   Bone Research

Cisplatin-Prodrug-Constructed Liposomes as a Versatile Theranostic Nanoplatform for Bimodal Imaging Guided Combination Cancer Therapy

(2016) Liangzhu Feng et al.   ADVANCED FUNCTIONAL MATERIALS

Inflammation, fracture and bone repair

(2016) Florence Loi et al.   BONE

Bone Turnover Markers in the Diagnosis and Monitoring of Metabolic Bone Disease

(2016) Matthew B. Greenblatt et al.   CLINICAL CHEMISTRY

LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption

(2016) Jian Luo et al.   NATURE MEDICINE

Physiological and pathophysiological bone turnover — role of the immune system

(2016) M. Neale Weitzmann et al.   Nature Reviews Endocrinology

GDF11 decreases bone mass by stimulating osteoclastogenesis and inhibiting osteoblast differentiation

(2016) Weiqing Liu et al.   Nature Communications

Detoxification of Organophosphate Poisoning Using Nanoparticle Bioscavengers

(2015) Zhiqing Pang et al.   ACS Nano

Cell-Membrane-Coated Synthetic Nanomotors for Effective Biodetoxification

(2015) Zhiguang Wu et al.   ADVANCED FUNCTIONAL MATERIALS

In vitro and in vivo studies on the degradation of high-purity Mg (99.99wt.%) screw with femoral intracondylar fractured rabbit model

(2015) Pei Han et al.   BIOMATERIALS

A dual function of copper in designing regenerative implants

(2015) Ines Burghardt et al.   BIOMATERIALS

Effects of TNF-α on Cementoblast Differentiation, Mineralization, and Apoptosis

(2015) Y.L. Wang et al.   JOURNAL OF DENTAL RESEARCH

Nanoparticle biointerfacing by platelet membrane cloaking

(2015) Che-Ming J. Hu et al.   NATURE

DNA methyltransferase 3a regulates osteoclast differentiation by coupling to an S-adenosylmethionine–producing metabolic pathway

(2015) Keizo Nishikawa et al.   NATURE MEDICINE

DDR2 (discoidin domain receptor 2) suppresses osteoclastogenesis and is a potential therapeutic target in osteoporosis

(2015) Y. Zhang et al.   Science Signaling

RANKL blockade prevents and treats aggressive osteosarcomas

(2015) Yan Chen et al.   Science Translational Medicine

Role of T-cell reconstitution in HIV-1 antiretroviral therapy-induced bone loss

(2015) Ighovwerha Ofotokun et al.   Nature Communications

DDR2 (discoidin domain receptor 2) suppresses osteoclastogenesis and is a potential therapeutic target in osteoporosis

(2015) Y. Zhang et al.   Science Signaling

Inhibition of Osteoclast Differentiation by Gold Nanoparticles Functionalized with Cyclodextrin Curcumin Complexes

(2014) Dong Nyoung Heo et al.   ACS Nano

The prevention of titanium-particle-induced osteolysis by OA-14 through the suppression of the p38 signaling pathway and inhibition of osteoclastogenesis

(2014) Bo Tian et al.   BIOMATERIALS

Manipulation of receptor oligomerization as a strategy to inhibit signaling by TNF superfamily members

(2014) J. T. Warren et al.   Science Signaling

Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation

(2014) Kyung-Hyun Park-Min et al.   Nature Communications

A biomimetic nanosponge that absorbs pore-forming toxins

(2013) Che-Ming J. Hu et al.   Nature Nanotechnology

Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis

(2012) Kazuhiro Maeda et al.   NATURE MEDICINE

Inflammatory bone loss: pathogenesis and therapeutic intervention

(2012) Kurt Redlich et al.   NATURE REVIEWS DRUG DISCOVERY

Effects of denosumab on bone turnover markers in postmenopausal osteoporosis

(2010) Richard Eastell et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The multiple faces of autoimmune-mediated bone loss

(2010) Georg Schett et al.   Nature Reviews Endocrinology

Novel functions for NFκB: inhibition of bone formation

(2010) Susan A. Krum et al.   Nature Reviews Rheumatology